ID ZN750_XENTR Reviewed; 671 AA.
AC Q28BT7; Q6DIF8;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 2.
DT 07-SEP-2016, entry version 53.
DE RecName: Full=Zinc finger protein 750;
GN Name=znf750; ORFNames=TNeu069m12.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Neurula;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor involved in epidermis
CC differentiation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Contains 1 C2H2-type zinc finger. {ECO:0000305}.
DR EMBL; CR942644; CAJ82741.1; -; mRNA.
DR EMBL; BC075584; AAH75584.1; -; mRNA.
DR RefSeq; NP_001004995.1; NM_001004995.1.
DR UniGene; Str.6731; -.
DR STRING; 8364.ENSXETP00000044280; -.
DR PaxDb; Q28BT7; -.
DR GeneID; 448470; -.
DR KEGG; xtr:448470; -.
DR CTD; 79755; -.
DR Xenbase; XB-GENE-5775684; znf750.
DR eggNOG; ENOG410IF50; Eukaryota.
DR eggNOG; ENOG410ZK89; LUCA.
DR HOGENOM; HOG000049178; -.
DR HOVERGEN; HBG080198; -.
DR InParanoid; Q28BT7; -.
DR OrthoDB; EOG091G036R; -.
DR TreeFam; TF331381; -.
DR Proteomes; UP000008143; Unassembled WGS sequence.
DR Bgee; ENSXETG00000020479; -.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; ISS:UniProtKB.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; ISS:UniProtKB.
DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
PE 2: Evidence at transcript level;
KW Activator; Complete proteome; Differentiation; Metal-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation; Zinc;
KW Zinc-finger.
FT CHAIN 1 671 Zinc finger protein 750.
FT /FTId=PRO_0000247074.
FT ZN_FING 25 46 C2H2-type; degenerate.
FT CONFLICT 513 513 I -> M (in Ref. 1; CAJ82741).
FT {ECO:0000305}.
SQ SEQUENCE 671 AA; 74240 MW; C5684C51BB9D0BAF CRC64;
MSLVKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITVVTDQD
RIVKNPKVNS TDQKQPSNEP FAKSPVPAIN GLTGLESKTQ HSVAREEAKE NFDLKNEAKP
HVEKTTVTKE VTLPPTAIIG QINKPPSLDG VMRPSAFIPV GEHRLKGTEN IKIPELSSVS
TEPAKGVHSI KSAFHSLPTP WKSGLVSPDF SHKSSIPRYI RPMISEYPPQ FYSETGLPAV
FSPYLFPQAE CENPMLSVYS APEQRPFLPH PLQASGLPLP KPINAPFEHY RLLQQFQQNP
QLHYGFYRPT EHPYFSYGLK VPPVPSLSKE HTSQSVDSPT FIYPSSHPSR LYPLEGFQKL
AEIQKETSPV PAKNLDSKSD SESVKMSPRA GSAATGSPGR PSPTNFTQNS QGHEGIFDLS
TKSTSDKAGK DFTSGKAVRK STDCQTTISR EHSPCFRNDE IQSHSDCYSD DAAPHDSVAP
LNLSKRPEVE DRAVFDTMHN SDSNDESVGF MEIQDLPLNL SVKDSGNNQK ALCADERLLL
PRQVTSSPNY HFIHTVDKRV PATTGVHSLG IIENCDEQKQ SAAVALCQLA TSSPGVPARG
TEDEFSEKET VAPEQVHPRA PAAQETEADI GARGQKRTNS KEPGKSQSSN KKHKSVDSGR
MFTLRKRPRV S
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