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MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).

Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
This form lets you build a HMMER2 profile-HMM from a multiple sequence alignment (MSA), and search the databases of protein sequences with it.
The HMMER2 package was written by Sean Eddy. Only those options that are most useful to build a profile from an MSA are available below.
Sequence Input



Mandatory parameters
seq_source sw - Swiss-Prot
bact - Some complete proteomes from Bacteria
arch - Some complete proteomes from Archaea
euk - Some complete proteomes from Eukaryota
ur50 - UniRef50
ur50_win20 - UniRef50 window shuffled (w=20)
ecoli - Escherichia coli K12 proteome

This service is very computer intensive, please be patient.