ID ZN568_HUMAN Reviewed; 644 AA.
AC Q3ZCX4; B4DS92; E7ER33; Q6N060; Q8NA64;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 2.
DT 30-NOV-2016, entry version 105.
DE RecName: Full=Zinc finger protein 568;
GN Name=ZNF568;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), AND NUCLEOTIDE
RP SEQUENCE [LARGE SCALE MRNA] OF 1-594 (ISOFORM 2).
RC TISSUE=Brain, and Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Retina;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-401 (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP POLYMORPHISM.
RX PubMed=23071813; DOI=10.1371/journal.pone.0047481;
RA Chien H.C., Wang H.Y., Su Y.N., Lai K.Y., Lu L.C., Chen P.C.,
RA Tsai S.F., Wu C.I., Hsieh W.S., Shen C.K.;
RT "Targeted disruption in mice of a neural stem cell-maintaining, KRAB-
RT Zn finger-encoding gene that has rapidly evolved in the human
RT lineage.";
RL PLoS ONE 7:E47481-E47481(2012).
CC -!- FUNCTION: Has transcriptional repression activity, together with
CC the corepressor TRIM28. Essential during embryonic development,
CC where it regulates convergent extension movements required for
CC axis elongation and tissue morphogenesis in all germ layers. Also
CC important for normal morphogenesis of extraembryonic tissues
CC including the yolk sac, extraembryonic mesoderm and placenta. May
CC enhance proliferation or maintenance of neural stem cells.
CC {ECO:0000250|UniProtKB:E9PYI1}.
CC -!- SUBUNIT: Interacts with TRIM28. {ECO:0000250|UniProtKB:E9PYI1}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:E9PYI1}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q3ZCX4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3ZCX4-2; Sequence=VSP_028556;
CC Name=3;
CC IsoId=Q3ZCX4-3; Sequence=VSP_028556, VSP_046815;
CC Note=Ref.1 (BAG61554) sequence is in conflict in position:
CC 542:L->P. {ECO:0000305};
CC -!- POLYMORPHISM: Isoform 3 is highly polymorphic with three major
CC alleles: H, C1 and C1. The H allele is found at higher frequencies
CC in Japanese (0.71) and Taiwan Chinese (0.72) populations compared
CC to European (0.45) and African (0.39) populations. The H allele
CC may be associated with smaller head size in infants.
CC {ECO:0000269|PubMed:23071813}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
CC -!- SIMILARITY: Contains 15 C2H2-type zinc fingers.
CC {ECO:0000255|PROSITE-ProRule:PRU00042}.
CC -!- SIMILARITY: Contains 1 KRAB domain. {ECO:0000255|PROSITE-
CC ProRule:PRU00119}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH31218.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
CC Sequence=AAH31218.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
CC Sequence=CAE45810.1; Type=Frameshift; Positions=436; Evidence={ECO:0000305};
DR EMBL; AK093123; BAC04064.1; -; mRNA.
DR EMBL; AK299626; BAG61554.1; -; mRNA.
DR EMBL; BX640681; CAE45810.1; ALT_FRAME; mRNA.
DR EMBL; AC008733; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC031218; AAH31218.1; ALT_SEQ; mRNA.
DR CCDS; CCDS42558.1; -. [Q3ZCX4-1]
DR CCDS; CCDS56092.1; -. [Q3ZCX4-2]
DR CCDS; CCDS56093.1; -. [Q3ZCX4-3]
DR RefSeq; NP_001191764.1; NM_001204835.1.
DR RefSeq; NP_001191765.1; NM_001204836.1. [Q3ZCX4-2]
DR RefSeq; NP_001191766.1; NM_001204837.1. [Q3ZCX4-2]
DR RefSeq; NP_001191767.1; NM_001204838.1.
DR RefSeq; NP_001191768.1; NM_001204839.1. [Q3ZCX4-3]
DR RefSeq; NP_940941.2; NM_198539.3. [Q3ZCX4-1]
DR RefSeq; XP_016882262.1; XM_017026773.1. [Q3ZCX4-2]
DR RefSeq; XP_016882263.1; XM_017026774.1. [Q3ZCX4-2]
DR RefSeq; XP_016882264.1; XM_017026775.1. [Q3ZCX4-3]
DR UniGene; Hs.404220; -.
DR UniGene; Hs.733385; -.
DR ProteinModelPortal; Q3ZCX4; -.
DR SMR; Q3ZCX4; -.
DR BioGrid; 131935; 2.
DR IntAct; Q3ZCX4; 1.
DR STRING; 9606.ENSP00000334685; -.
DR iPTMnet; Q3ZCX4; -.
DR PhosphoSitePlus; Q3ZCX4; -.
DR BioMuta; ZNF568; -.
DR DMDM; 158706494; -.
DR MaxQB; Q3ZCX4; -.
DR PaxDb; Q3ZCX4; -.
DR PeptideAtlas; Q3ZCX4; -.
DR PRIDE; Q3ZCX4; -.
DR Ensembl; ENST00000333987; ENSP00000334685; ENSG00000198453. [Q3ZCX4-1]
DR Ensembl; ENST00000415168; ENSP00000394514; ENSG00000198453. [Q3ZCX4-2]
DR Ensembl; ENST00000455427; ENSP00000413396; ENSG00000198453. [Q3ZCX4-3]
DR Ensembl; ENST00000619231; ENSP00000481819; ENSG00000198453. [Q3ZCX4-1]
DR GeneID; 374900; -.
DR KEGG; hsa:374900; -.
DR UCSC; uc002ofc.4; human. [Q3ZCX4-1]
DR CTD; 374900; -.
DR DisGeNET; 374900; -.
DR GeneCards; ZNF568; -.
DR HGNC; HGNC:25392; ZNF568.
DR HPA; HPA052061; -.
DR neXtProt; NX_Q3ZCX4; -.
DR OpenTargets; ENSG00000198453; -.
DR PharmGKB; PA134893477; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00860000133681; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR InParanoid; Q3ZCX4; -.
DR KO; K09228; -.
DR OMA; SIHKRGH; -.
DR OrthoDB; EOG091G02KC; -.
DR PhylomeDB; Q3ZCX4; -.
DR TreeFam; TF337898; -.
DR BioCyc; ZFISH:G66-31842-MONOMER; -.
DR Reactome; R-HSA-212436; Generic Transcription Pathway.
DR GenomeRNAi; 374900; -.
DR PRO; PR:Q3ZCX4; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000198453; -.
DR CleanEx; HS_ZNF568; -.
DR ExpressionAtlas; Q3ZCX4; baseline and differential.
DR Genevisible; Q3ZCX4; HS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 3.30.160.60; -; 15.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR007087; Znf_C2H2.
DR InterPro; IPR015880; Znf_C2H2-like.
DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 9.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF109640; SSF109640; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 15.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE 2: Evidence at transcript level;
KW Alternative splicing; Complete proteome; Developmental protein;
KW DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome;
KW Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 644 Zinc finger protein 568.
FT /FTId=PRO_0000306877.
FT DOMAIN 48 119 KRAB. {ECO:0000255|PROSITE-
FT ProRule:PRU00119}.
FT ZN_FING 222 244 C2H2-type 1. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 250 272 C2H2-type 2. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 278 300 C2H2-type 3. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 306 328 C2H2-type 4. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 334 356 C2H2-type 5. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 362 384 C2H2-type 6. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 390 412 C2H2-type 7. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 418 440 C2H2-type 8. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 446 468 C2H2-type 9. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 474 496 C2H2-type 10. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 502 524 C2H2-type 11. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 530 552 C2H2-type 12. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 558 580 C2H2-type 13. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 586 608 C2H2-type 14. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 614 636 C2H2-type 15. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT VAR_SEQ 1 64 Missing (in isoform 2 and isoform 3).
FT {ECO:0000303|PubMed:14702039,
FT ECO:0000303|PubMed:17974005}.
FT /FTId=VSP_028556.
FT VAR_SEQ 121 644 VWEVDEQIKKQQETLVRKVTSISKKILIKEKVIECKKVAKI
FT FPLSSDIVTSRQSFYDCDSLDKGLEHNLDLLRYEKGCVREK
FT QSNEFGKPFYHCASYVVTPFKCNQCGQDFSHKFDLIRHERI
FT HAGEKPYECKECGKAFSRKENLITHQKIHTGEKPYKCNECG
FT KAFIQMSNLIRHHRIHTGEKPYACKDCWKAFSQKSNLIEHE
FT RIHTGEKPYECKECGKSFSQKQNLIEHEKIHTGEKPYACNE
FT CGRAFSRMSSVTLHMRSHTGEKPYKCNKCGKAFSQCSVFII
FT HMRSHTGEKPYVCSECGKAFSQSSSLTVHMRNHTAEKPYEC
FT KECGKAFSRKENLITHQKIHTGEKPYECSECGKAFIQMSNL
FT IRHQRIHTGEKPYACTVCGKAFSQKSNLTEHEKIHTGEKPY
FT HCNQCGKAFSQRQNLLEHEKIHTGEKPFKCNECGKAFSRIS
FT SLTLHVRSHTGEKPYECNKCGKAFSQCSLLIIHMRSHTGEK
FT PFECNECGKAFSQRASLSIHKRGHTGERHQVY -> PRRGE
FT NCCASEVMAEGLKFKDVVIYFSQKEWECLHSAQKDLYRDVM
FT LENYGNLVLLGLSDTKPNVISLLEQKKEPWMVKRKETKEWC
FT PDWEFGRETKNLSPKENIYEIRSPQQEKARVIREIRCQVER
FT QQGHQEGHFRPAVIPFTSMQCTAHREYQWLHTGEKSCECRK
FT CKNAFRYQSCPIQHEIIHNKEKEPECGECRKIFNSGSDLIK
FT HQTLHESKKHSENNKCAFNHDSGITQPQSINTGEKPHKCKE
FT CGKAFRSSSQISQHQRMHLGEKPYKCRECGKAFPSTAQLNL
FT HQRIHTDEKYYESKACGKAFTRPSHLFRHQRIHTGEKPHKC
FT KECGKAFRYDTQLSLHQIIHTGERRYECRECGKVYSCASQL
FT SLHQRIHTGEKPHECKECGKAFISDSHLIRHQSVHTGEKPC
FT KCKECGKSFRRGSELTRHQRAHTGEKPYECKECEKAFTCST
FT ELVRHQKVHTGERPHKCKECGKAFIRRSELTHHERSHTGEK
FT PYECKECGKPFGGGSELS (in isoform 3).
FT {ECO:0000303|PubMed:14702039}.
FT /FTId=VSP_046815.
FT VARIANT 437 437 M -> T (in dbSNP:rs547483).
FT /FTId=VAR_052867.
FT VARIANT 642 642 Q -> R (in dbSNP:rs1644634).
FT /FTId=VAR_052868.
FT CONFLICT 96 96 V -> M (in Ref. 4; AAH31218).
FT {ECO:0000305}.
FT CONFLICT 128 128 I -> V (in Ref. 2; CAE45810).
FT {ECO:0000305}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 560 580 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 474 496 ismart:ZnF_C2H2 [T]
FT MYHIT 586 608 ismart:ZnF_C2H2 [T]
FT MYHIT 334 356 ismart:ZnF_C2H2 [T]
FT MYHIT 530 557 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 474 501 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 392 412 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 48 88 ipfam:KRAB [T]
FT MYHIT 616 636 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 280 300 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 252 272 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 390 417 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 308 328 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 306 328 ismart:ZnF_C2H2 [T]
FT MYHIT 224 244 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 502 529 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 306 333 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 390 412 ismart:ZnF_C2H2 [T]
FT MYHIT 502 524 ismart:ZnF_C2H2 [T]
FT MYHIT 362 389 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 558 580 ismart:ZnF_C2H2 [T]
FT MYHIT 588 608 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 446 473 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 614 641 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 530 552 ismart:ZnF_C2H2 [T]
FT MYHIT 446 468 ismart:ZnF_C2H2 [T]
FT MYHIT 558 585 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 362 384 ismart:ZnF_C2H2 [T]
FT MYHIT 418 440 ismart:ZnF_C2H2 [T]
FT MYHIT 532 552 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 420 440 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 222 244 ismart:ZnF_C2H2 [T]
FT MYHIT 334 361 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 586 613 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 476 496 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 278 305 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 418 445 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 364 384 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 448 468 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 278 300 ismart:ZnF_C2H2 [T]
FT MYHIT 48 108 ismart:KRAB [T]
FT MYHIT 614 636 ismart:ZnF_C2H2 [T]
FT MYHIT 48 119 iprf:KRAB [T]
FT MYHIT 336 356 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 222 249 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 504 524 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 250 272 ismart:ZnF_C2H2 [T]
FT MYHIT 250 277 iprf:ZINC_FINGER_C2H2_2 [T]
SQ SEQUENCE 644 AA; 74369 MW; CEEED67D5D8E7DA2 CRC64;
MTSQSSVISN SCVTMERLSH MMERKAWCSQ ESALSEEEED TTRPLETVTF KDVAVDLTQE
EWEQMKPAQR NLYRDVMLEN YSNLVTVGCQ VTKPDVIFKL EQEEEPWVME EEMFGRHCPE
VWEVDEQIKK QQETLVRKVT SISKKILIKE KVIECKKVAK IFPLSSDIVT SRQSFYDCDS
LDKGLEHNLD LLRYEKGCVR EKQSNEFGKP FYHCASYVVT PFKCNQCGQD FSHKFDLIRH
ERIHAGEKPY ECKECGKAFS RKENLITHQK IHTGEKPYKC NECGKAFIQM SNLIRHHRIH
TGEKPYACKD CWKAFSQKSN LIEHERIHTG EKPYECKECG KSFSQKQNLI EHEKIHTGEK
PYACNECGRA FSRMSSVTLH MRSHTGEKPY KCNKCGKAFS QCSVFIIHMR SHTGEKPYVC
SECGKAFSQS SSLTVHMRNH TAEKPYECKE CGKAFSRKEN LITHQKIHTG EKPYECSECG
KAFIQMSNLI RHQRIHTGEK PYACTVCGKA FSQKSNLTEH EKIHTGEKPY HCNQCGKAFS
QRQNLLEHEK IHTGEKPFKC NECGKAFSRI SSLTLHVRSH TGEKPYECNK CGKAFSQCSL
LIIHMRSHTG EKPFECNECG KAFSQRASLS IHKRGHTGER HQVY
//
|
