Legends: 1, Phosphoserine. {ECO:0000250|UniProtKB:O15209}; 2, BTB. {ECO:0000255|PROSITE- ProRule:PRU00037}; 3, ZN_FING C2H2-type 1; atypical. {ECO:0000255|PROSITE-ProRule:PRU00042}; 4, ZN_FING C2H2-type 2. {ECO:0000255|PROSITE- ProRule:PRU00042}; 5, ZN_FING C2H2-type 3. {ECO:0000255|PROSITE- ProRule:PRU00042}; 6, ismart:ZnF_C2H2 [T]; 7, iprf:ZINC_FINGER_C2H2_2 [T]; 8, iprf:BTB [T]; 9, ipat:ZINC_FINGER_C2H2_1 [T].
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ID ZBT22_MOUSE Reviewed; 638 AA.
AC Q9Z0G7;
DT 19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 30-NOV-2016, entry version 138.
DE RecName: Full=Zinc finger and BTB domain-containing protein 22;
DE AltName: Full=Protein BING1;
DE AltName: Full=Zinc finger protein 297;
GN Name=Zbtb22; Synonyms=Bing1, Zfp297, Znf297;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=129/SvJ;
RA Rowen L., Qin S., Madan A., Loretz C., James R., Dors M., Mix L.,
RA Hall J., Lasky S., Hood L.;
RT "Sequence of the mouse major histocompatibility complex class II
RT region.";
RL Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and FVB/N; TISSUE=Embryo, and Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
CC -!- SIMILARITY: Contains 1 BTB (POZ) domain. {ECO:0000255|PROSITE-
CC ProRule:PRU00037}.
CC -!- SIMILARITY: Contains 3 C2H2-type zinc fingers.
CC {ECO:0000255|PROSITE-ProRule:PRU00042}.
DR EMBL; AF110520; AAC97972.1; -; Genomic_DNA.
DR EMBL; AF100956; AAC69892.1; -; Genomic_DNA.
DR EMBL; BC026964; AAH26964.1; -; mRNA.
DR EMBL; BC052154; AAH52154.1; -; mRNA.
DR CCDS; CCDS28634.1; -.
DR RefSeq; NP_065650.1; NM_020625.3.
DR UniGene; Mm.482096; -.
DR ProteinModelPortal; Q9Z0G7; -.
DR SMR; Q9Z0G7; -.
DR BioGrid; 219885; 2.
DR STRING; 10090.ENSMUSP00000057466; -.
DR iPTMnet; Q9Z0G7; -.
DR PhosphoSitePlus; Q9Z0G7; -.
DR PaxDb; Q9Z0G7; -.
DR PRIDE; Q9Z0G7; -.
DR Ensembl; ENSMUST00000053429; ENSMUSP00000057466; ENSMUSG00000051390.
DR GeneID; 81630; -.
DR KEGG; mmu:81630; -.
DR UCSC; uc008cac.1; mouse.
DR CTD; 9278; -.
DR MGI; MGI:1931870; Zbtb22.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119063; -.
DR HOGENOM; HOG000231975; -.
DR HOVERGEN; HBG056510; -.
DR InParanoid; Q9Z0G7; -.
DR KO; K10502; -.
DR OMA; VEMGFSG; -.
DR OrthoDB; EOG091G06Z9; -.
DR PhylomeDB; Q9Z0G7; -.
DR ChiTaRS; Zbtb22; mouse.
DR PRO; PR:Q9Z0G7; -.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000051390; -.
DR ExpressionAtlas; Q9Z0G7; baseline and differential.
DR Genevisible; Q9Z0G7; MM.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; -; 3.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ.
DR InterPro; IPR029833; ZBT22/43.
DR InterPro; IPR007087; Znf_C2H2.
DR InterPro; IPR015880; Znf_C2H2-like.
DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR PANTHER; PTHR24414:SF4; PTHR24414:SF4; 3.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 2: Evidence at transcript level;
KW Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW Phosphoprotein; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 638 Zinc finger and BTB domain-containing
FT protein 22.
FT /FTId=PRO_0000047518.
FT DOMAIN 57 121 BTB. {ECO:0000255|PROSITE-
FT ProRule:PRU00037}.
FT ZN_FING 483 504 C2H2-type 1; atypical.
FT {ECO:0000255|PROSITE-ProRule:PRU00042}.
FT ZN_FING 510 532 C2H2-type 2. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 538 559 C2H2-type 3. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT MOD_RES 203 203 Phosphoserine.
FT {ECO:0000250|UniProtKB:O15209}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 538 559 ismart:ZnF_C2H2 [T]
FT MYHIT 483 504 ismart:ZnF_C2H2 [T]
FT MYHIT 510 537 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 483 509 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 538 564 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 57 121 iprf:BTB [T]
FT MYHIT 47 149 ipfam:BTB [T]
FT MYHIT 512 532 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 57 151 ismart:BTB [T]
FT MYHIT 510 532 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 638 AA; 66029 MW; 40343A4C6CB5EF6C CRC64;
MEPSALSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS
IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA
AADIVNFLTV GSVLQMWHIV DKCTELLREG RSAATTTTVT TAAAPSVSVP CASVPSGNGG
TVAPATVGSV RSHTSSRASE NQSPSSSNYF SPRESTDFSS TSQDAFVASA AGSGNRRDGG
PVFPAPVVGS AGTTSGKLLL EADELCDDGG DGRGAVAPGA GLRRSNCMPA SAVPQKHWVY
VKQARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDEE MGGGSGVPAG GEPEATLSIS
DVRTLTEPAD KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP GGPTPSSYAL THPPRPLLPL
DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA VTLGGTSAVG LGIPSGSGGA PGGTGNSDGN
KIFLCHCGKA FSHKSMRDRH VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC
SVCAKKFMWR DSFMRHRGHC ERRHRMGVGG VGSGPGPGPG PGTPSGPALQ PKRESSTVGG
GSGDEANSAT PPSHRRVWSP PSVHKVEMDF SGGGGAAH
//
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