MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Transcriptional regulatory protein WalR {ECO:0000305}; |
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| MyHits synonyms | WALR_STAAT , A8YYU1 , BFA71D9C2464F600 |
 Legends: 1, 4-aspartylphosphate. {ECO:0000255|PROSITE-ProRule:PRU00169}; 2, Response regulatory. {ECO:0000255|PROSITE-ProRule:PRU00169}; 3, DNA_BIND OmpR/PhoB-type. {ECO:0000255|PROSITE- ProRule:PRU01091}.
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ID WALR_STAAT Reviewed; 233 AA.
AC A8YYU1;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 2.
DT 02-NOV-2016, entry version 60.
DE RecName: Full=Transcriptional regulatory protein WalR {ECO:0000305};
GN Name=walR; Synonyms=yycF; OrderedLocusNames=USA300HOU_0018;
OS Staphylococcus aureus (strain USA300 / TCH1516).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=451516;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USA300 / TCH1516;
RX PubMed=17986343; DOI=10.1186/1471-2180-7-99;
RA Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S.,
RA Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y.,
RA Igboeli O., Petrosino J., Tirumalai M., Uzman A., Fox G.E.,
RA Cardenas A.M., Muzny D.M., Hemphill L., Ding Y., Dugan S., Blyth P.R.,
RA Buhay C.J., Dinh H.H., Hawes A.C., Holder M., Kovar C.L., Lee S.L.,
RA Liu W., Nazareth L.V., Wang Q., Zhou J., Kaplan S.L., Weinstock G.M.;
RT "Subtle genetic changes enhance virulence of methicillin resistant and
RT sensitive Staphylococcus aureus.";
RL BMC Microbiol. 7:99-99(2007).
CC -!- FUNCTION: Member of the two-component regulatory system WalK/WalR
CC that regulates genes involved in autolysis, biofilm formation and
CC cell wall metabolism. {ECO:0000250|UniProtKB:Q2G2U6}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- PTM: Phosphorylated by WalK. {ECO:0000250|UniProtKB:Q2G2U6}.
CC -!- SIMILARITY: Contains 1 OmpR/PhoB-type DNA-binding domain.
CC {ECO:0000255|PROSITE-ProRule:PRU01091}.
CC -!- SIMILARITY: Contains 1 response regulatory domain.
CC {ECO:0000255|PROSITE-ProRule:PRU00169}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABX28064.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR EMBL; CP000730; ABX28064.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_000101976.1; NC_010079.1.
DR ProteinModelPortal; A8YYU1; -.
DR SMR; A8YYU1; -.
DR EnsemblBacteria; ABX28064; ABX28064; USA300HOU_0018.
DR GeneID; 28379619; -.
DR KEGG; sax:USA300HOU_0018; -.
DR PATRIC; 19595023; VBIStaAur36919_0051.
DR HOGENOM; HOG000034819; -.
DR KO; K07668; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Activator; Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1 233 Transcriptional regulatory protein WalR.
FT /FTId=PRO_0000353044.
FT DOMAIN 4 117 Response regulatory.
FT {ECO:0000255|PROSITE-ProRule:PRU00169}.
FT DNA_BIND 132 231 OmpR/PhoB-type. {ECO:0000255|PROSITE-
FT ProRule:PRU01091}.
FT MOD_RES 53 53 4-aspartylphosphate.
FT {ECO:0000255|PROSITE-ProRule:PRU00169}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 132 231 iprf:OMPR_PHOB [T]
FT MYHIT 153 229 ipfam:Trans_reg_C [T]
FT MYHIT 5 114 ipfam:Response_reg [T]
FT MYHIT 153 229 ismart:Trans_reg_C [T]
FT MYHIT 4 117 iprf:RESPONSE_REGULATORY [T]
FT MYHIT 3 113 ismart:REC [T]
SQ SEQUENCE 233 AA; 27192 MW; BFA71D9C2464F600 CRC64;
MARKVVVVDD EKPIADILEF NLKKEGYDVY CAYDGNDAVD LIYEEEPDIV LLDIMLPGRD
GMEVCREVRK KYEMPIIMLT AKDSEIDKVL GLELGADDYV TKPFSTRELI ARVKANLRRH
YSQPAQDTGN VTNEITIKDI VIYPDAYSIK KRGEDIELTH REFELFHYLS KHMGQVMTRE
HLLQTVWGYD YFGDVRTVDV TIRRLREKIE DDPSHPEYIV TRRGVGYFLQ QHE
//
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