Legends: 1, ZN_FING RING-type. {ECO:0000255|PROSITE- ProRule:PRU00175}; 2, ZN_FING B box-type. {ECO:0000255|PROSITE- ProRule:PRU00024}; 3, COILED {ECO:0000255}; 4, COMPBIAS Poly-Glu; 5, ismart:BBOX [T]; 6, iprf:ZF_RING_2 [T]; 7, ismart:RING [T]; 8, ismart:PRY [T]; 9, iprf:ZF_BBOX [T]; 10, ipfam:zf-B_box [T]; 11, ipfam:PRY [T].
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ID TRI26_RAT Reviewed; 542 AA.
AC P62603; Q6MFZ0;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 18-JAN-2017, entry version 94.
DE RecName: Full=Tripartite motif-containing protein 26;
DE AltName: Full=Zinc finger protein 173;
GN Name=Trim26; Synonyms=Znf173;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway;
RX PubMed=15060004; DOI=10.1101/gr.1987704;
RA Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T.,
RA Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT "The genomic sequence and comparative analysis of the rat major
RT histocompatibility complex.";
RL Genome Res. 14:631-639(2004).
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family. {ECO:0000305}.
CC -!- SIMILARITY: Contains 1 B box-type zinc finger.
CC {ECO:0000255|PROSITE-ProRule:PRU00024}.
CC -!- SIMILARITY: Contains 1 B30.2/SPRY domain. {ECO:0000255|PROSITE-
CC ProRule:PRU00548}.
CC -!- SIMILARITY: Contains 1 RING-type zinc finger.
CC {ECO:0000255|PROSITE-ProRule:PRU00175}.
DR EMBL; BX883051; CAE84057.1; -; Genomic_DNA.
DR RefSeq; NP_001011665.1; NM_001011665.2.
DR UniGene; Rn.163420; -.
DR ProteinModelPortal; P62603; -.
DR STRING; 10116.ENSRNOP00000001019; -.
DR PaxDb; P62603; -.
DR PRIDE; P62603; -.
DR Ensembl; ENSRNOT00000001019; ENSRNOP00000001019; ENSRNOG00000032930.
DR GeneID; 309586; -.
DR KEGG; rno:309586; -.
DR UCSC; RGD:1359126; rat.
DR CTD; 7726; -.
DR RGD; 1359126; Trim26.
DR eggNOG; KOG2177; Eukaryota.
DR eggNOG; ENOG410Z766; LUCA.
DR GeneTree; ENSGT00760000118893; -.
DR HOGENOM; HOG000234133; -.
DR HOVERGEN; HBG001357; -.
DR InParanoid; P62603; -.
DR KO; K12008; -.
DR Reactome; R-RNO-877300; Interferon gamma signaling.
DR PRO; PR:P62603; -.
DR Proteomes; UP000002494; Chromosome 20.
DR Bgee; ENSRNOG00000032930; -.
DR ExpressionAtlas; P62603; baseline.
DR Genevisible; P62603; RN.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR Gene3D; 4.10.45.10; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR003879; Butyrophylin.
DR InterPro; IPR013320; ConA-like_dom.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; SSF49899; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil; Complete proteome; Metal-binding; Reference proteome;
KW Zinc; Zinc-finger.
FT CHAIN 1 542 Tripartite motif-containing protein 26.
FT /FTId=PRO_0000056239.
FT DOMAIN 298 542 B30.2/SPRY. {ECO:0000255|PROSITE-
FT ProRule:PRU00548}.
FT ZN_FING 16 57 RING-type. {ECO:0000255|PROSITE-
FT ProRule:PRU00175}.
FT ZN_FING 97 138 B box-type. {ECO:0000255|PROSITE-
FT ProRule:PRU00024}.
FT COILED 197 243 {ECO:0000255}.
FT COILED 411 440 {ECO:0000255}.
FT COMPBIAS 384 403 Poly-Glu.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 97 138 ismart:BBOX [T]
FT MYHIT 16 57 iprf:ZF_RING_2 [T]
FT MYHIT 16 56 ismart:RING [T]
FT MYHIT 298 542 iprf:B302_SPRY [T]
FT MYHIT 315 367 ismart:PRY [T]
FT MYHIT 368 542 ismart:SPRY [T]
FT MYHIT 97 138 iprf:ZF_BBOX [T]
FT MYHIT 437 534 ipfam:SPRY [T]
FT MYHIT 98 136 ipfam:zf-B_box [T]
FT MYHIT 318 366 ipfam:PRY [T]
SQ SEQUENCE 542 AA; 62631 MW; 88C87B17F9E57BA6 CRC64;
MAVSAPLRSL EEEVTCSICL DYLRDPVTID CGHVFCRSCT SDIRPISGNR PVCPLCKKPF
KKENIRPVWQ LASLVENIER LKVDNGKQPG ELAREPQDMK LCERHQEKLH YYCEDDGKLL
CVMCRESREH RPHTAVLVEK AALPHREKIL NHLNTLRRDR DKIQGFQAKG EADILAALTK
LQEQRQYIVA EFKQGHQFLK KREQHLLDQL ATLEQLLTEG REKFKTRGVS ELDRLTLVIS
ELEGKARQPA AELMQLSDRL SCLSLRYPRK KFWIGKAIPH MVKRKAGEFS DKLLSLQRGL
RQFQGKLLRD LEYKTVSVTL DPQSASGYLQ LSEDWKCITY TGQYQSDCLL PQQFDCEPGV
LGSKGFTWGK VYWEVELERE GWSEDEEEGE EEEEGEEEEE DEEPGYGDRY EDWETDEEDE
SLGEEEEEEE EEEEEVQESC MVGVAKDSVK RKGNLSLRPE DGVWALRLSP SGIWANTSPE
AQLFPVLRPR RVGIALDYEG GTVTFTNAES QELIYTFTTT FTRRLVPFLW LKWPEARLLL
RP
//
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