ID TM251_CHICK Reviewed; 131 AA.
AC Q5ZLR7;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 2.
DT 18-JAN-2017, entry version 70.
DE RecName: Full=Transmembrane protein 251;
GN Name=TMEM251; ORFNames=RCJMB04_5b13;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
OC Phasianidae; Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J.,
RA Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M.,
RA Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM251 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAG31326.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
DR EMBL; AJ719667; CAG31326.1; ALT_INIT; mRNA.
DR RefSeq; NP_001073200.1; NM_001079732.1.
DR UniGene; Gga.22630; -.
DR PaxDb; Q5ZLR7; -.
DR Ensembl; ENSGALT00000028074; ENSGALP00000028021; ENSGALG00000017387.
DR GeneID; 423422; -.
DR KEGG; gga:423422; -.
DR CTD; 26175; -.
DR eggNOG; ENOG410IVYY; Eukaryota.
DR eggNOG; ENOG4111FFW; LUCA.
DR GeneTree; ENSGT00390000007473; -.
DR HOGENOM; HOG000111822; -.
DR HOVERGEN; HBG058826; -.
DR InParanoid; Q5ZLR7; -.
DR OMA; LPFWFWT; -.
DR OrthoDB; EOG091G14P1; -.
DR PhylomeDB; Q5ZLR7; -.
DR TreeFam; TF332722; -.
DR PRO; PR:Q5ZLR7; -.
DR Proteomes; UP000000539; Chromosome 5.
DR Bgee; ENSGALG00000017387; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR028024; TMEM251.
DR Pfam; PF15190; TMEM251; 1.
DR ProDom; PD641273; PD641273; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1 131 Transmembrane protein 251.
FT /FTId=PRO_0000089915.
FT TRANSMEM 8 28 Helical. {ECO:0000255}.
FT TRANSMEM 66 86 Helical. {ECO:0000255}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 2 129 ipfam:TMEM251 [T]
SQ SEQUENCE 131 AA; 15363 MW; 8594B5E0A35F8D04 CRC64;
MMNFRQRMGW IGVGLYLLAS AAAFYYVFEI NETYNKLALE HIQQHPQEPQ EGTTWTHSLK
VRLLSLPFWL WTIIFLIPYL QMFLFLYSCT RADPKTVGYC IIPICLAVIC NRHQTFVKAS
NQISRLQLID T
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