ID TM223_DANRE Reviewed; 248 AA.
AC Q6DC58;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 07-SEP-2016, entry version 65.
DE RecName: Full=Transmembrane protein 223;
GN Name=tmem223; ORFNames=zgc:101024;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM223 family. {ECO:0000305}.
DR EMBL; BC078226; AAH78226.1; -; mRNA.
DR RefSeq; NP_001003594.1; NM_001003594.2.
DR UniGene; Dr.134772; -.
DR PaxDb; Q6DC58; -.
DR Ensembl; ENSDART00000101201; ENSDARP00000091975; ENSDARG00000069494.
DR GeneID; 445200; -.
DR KEGG; dre:445200; -.
DR CTD; 79064; -.
DR ZFIN; ZDB-GENE-040801-113; tmem223.
DR eggNOG; ENOG410IWJD; Eukaryota.
DR eggNOG; ENOG4111M6M; LUCA.
DR GeneTree; ENSGT00390000012589; -.
DR HOGENOM; HOG000008386; -.
DR InParanoid; Q6DC58; -.
DR OMA; NGITICS; -.
DR OrthoDB; EOG091G0W7I; -.
DR PhylomeDB; Q6DC58; -.
DR TreeFam; TF324862; -.
DR PRO; PR:Q6DC58; -.
DR Proteomes; UP000000437; Chromosome 21.
DR Bgee; ENSDARG00000069494; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0007399; P:nervous system development; IBA:GO_Central.
DR InterPro; IPR026100; Tmem223.
DR PANTHER; PTHR14549; PTHR14549; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1 248 Transmembrane protein 223.
FT /FTId=PRO_0000360422.
FT TRANSMEM 46 68 Helical. {ECO:0000255}.
FT TRANSMEM 84 104 Helical. {ECO:0000255}.
FT TRANSMEM 140 160 Helical. {ECO:0000255}.
SQ SEQUENCE 248 AA; 28081 MW; 27D588AB90BCCDBB CRC64;
MAVQHLLFGV RRSCTFILAC RRTAFQSSRA FTSIYTQFKV TDTKNIFRPL VFPVRVASAF
TFTSAAVAKD VLLFEHDRTR FFRLLAIFCG GQFLFWAYLG HFAFTSLRDT RKYSEPQKVR
TELGGFFSFD MNLGSNAWRY GFTSGCLIIG GGILALALLF SRRSVSRVIL HKGGAKVSVY
TQSPLGPQRS HHLTVPLSQV ACYAHRQESH SFIPLKVKGY KFYFLLDKEG TVNNPKLFDI
TVGAYRPL
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