Entry sw:RUVB_HELMI

ID   RUVB_HELMI              Reviewed;         370 AA.
AC   B0TF70;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   02-NOV-2016, entry version 58.
DE   RecName: Full=Holliday junction ATP-dependent DNA helicase RuvB {ECO:0000255|HAMAP-Rule:MF_00016};
DE            EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_00016};
GN   Name=ruvB {ECO:0000255|HAMAP-Rule:MF_00016};
GN   OrderedLocusNames=Helmi_17620; ORFNames=HM1_1829;
OS   Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Heliobacteriaceae;
OC   Heliobacterium.
OX   NCBI_TaxID=498761;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51547 / Ice1;
RX   PubMed=18441057; DOI=10.1128/JB.00299-08;
RA   Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA   Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA   Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L.,
RA   Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT   "The genome of Heliobacterium modesticaldum, a phototrophic
RT   representative of the Firmicutes containing the simplest
RT   photosynthetic apparatus.";
RL   J. Bacteriol. 190:4687-4696(2008).
CC   -!- FUNCTION: The RuvA-RuvB complex in the presence of ATP renatures
CC       cruciform structure in supercoiled DNA with palindromic sequence,
CC       indicating that it may promote strand exchange reactions in
CC       homologous recombination. RuvAB is a helicase that mediates the
CC       Holliday junction migration by localized denaturation and
CC       reannealing. {ECO:0000255|HAMAP-Rule:MF_00016}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000255|HAMAP-Rule:MF_00016}.
CC   -!- SUBUNIT: Forms a complex with RuvA. {ECO:0000255|HAMAP-
CC       Rule:MF_00016}.
CC   -!- SIMILARITY: Belongs to the RuvB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00016}.
DR   EMBL; CP000930; ABZ84387.1; -; Genomic_DNA.
DR   RefSeq; WP_012282891.1; NC_010337.2.
DR   ProteinModelPortal; B0TF70; -.
DR   STRING; 498761.HM1_1829; -.
DR   PRIDE; B0TF70; -.
DR   EnsemblBacteria; ABZ84387; ABZ84387; HM1_1829.
DR   KEGG; hmo:HM1_1829; -.
DR   PATRIC; 22107749; VBIHelMod36755_1636.
DR   eggNOG; ENOG4105CKJ; Bacteria.
DR   eggNOG; COG2255; LUCA.
DR   HOGENOM; HOG000218623; -.
DR   KO; K03551; -.
DR   OMA; YEPYLMQ; -.
DR   OrthoDB; POG091H00GH; -.
DR   Proteomes; UP000008550; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0009378; F:four-way junction helicase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-HAMAP.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00016; DNA_helic_RuvB; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004605; DNA_helicase_Holl-junc_RuvB.
DR   InterPro; IPR008823; DNA_helicase_Holl-junc_RuvB_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008824; RuvB_N.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF05491; RuvB_C; 1.
DR   Pfam; PF05496; RuvB_N; 1.
DR   ProDom; PD005323; DNA_helicase_Holl-junc_RuvB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00635; ruvB; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; DNA damage; DNA recombination;
KW   DNA repair; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome; SOS response.
FT   CHAIN         1    370       Holliday junction ATP-dependent DNA
FT                                helicase RuvB.
FT                                /FTId=PRO_1000089649.
FT   NP_BIND      60     67       ATP. {ECO:0000255|HAMAP-Rule:MF_00016}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT         5    235       ipfam:RuvB_N [T]
FT   MYHIT         1    370       ihamap:DNA_helic_RuvB [T]
FT   MYHIT       254    327       ipfam:RuvB_C [T]
FT   MYHIT        52    185       ismart:AAA [T]
SQ   SEQUENCE   370 AA;  40527 MW;  330C5254892D7FE8 CRC64;
     MDERMMTSAK RPEDRETEWS LRPRTLREYI GQDKLKENLT VFIQAALGRR EPLDHVLLYG
     PPGLGKTTLA QIIAQELGVQ LRVTSGPAIE RPGDLAAILT NLQPMDVLFI DEIHRLNRAV
     EEVLYPAMED FCLDIVIGKG PAARSIRIDL PRFTLVGATT RAGMLTSPLR DRFGVIHRLE
     YYRPDELEFI ILRAATILGV TAEPEGAREI ALRSRGTPRI ANRLLKRVRD YAQVLSDGVV
     TGEVAREALR RLEVDPRGLD TTDQRLLEAL IRKFAGGPVG VETLAASVGE SVDTVEDVVE
     PYLMQLGFLN RTPRGRMATI AACAHLGVPV PAGLLALQEG RPALLPSATD DTSSTAVGAA
     AEQAALSFDE
//