ID RFC3_ARATH Reviewed; 354 AA.
AC Q8VXX4;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 30-NOV-2016, entry version 107.
DE RecName: Full=Replication factor C subunit 3;
DE Short=AtRFC3;
DE AltName: Full=Activator 1 subunit 3;
DE AltName: Full=Protein EMBRYO DEFECTIVE 161;
DE AltName: Full=Protein EMBRYO DEFECTIVE 251;
DE AltName: Full=Protein EMBRYO DEFECTIVE 2775;
GN Name=RFC3; Synonyms=EMB161, EMB251, EMB2775, RFC5;
GN OrderedLocusNames=At5g27740; ORFNames=T1G16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K.,
RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S.,
RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M.,
RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R.,
RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J.,
RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M.,
RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M.,
RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P.,
RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C.,
RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N.,
RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S.,
RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W.,
RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S.,
RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R.,
RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W.,
RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis
RT thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RG The Arabidopsis Information Resource (TAIR);
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: May be involved in DNA replication and thus regulate
CC cell proliferation. {ECO:0000250}.
CC -!- SUBUNIT: Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that
CC can form a complex with RFC1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000305}.
DR EMBL; AC069556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93720.1; -; Genomic_DNA.
DR EMBL; AY074381; AAL67077.1; -; mRNA.
DR EMBL; AY091236; AAM14175.1; -; mRNA.
DR RefSeq; NP_198126.1; NM_122656.5.
DR UniGene; At.19785; -.
DR ProteinModelPortal; Q8VXX4; -.
DR SMR; Q8VXX4; -.
DR STRING; 3702.AT5G27740.1; -.
DR PaxDb; Q8VXX4; -.
DR EnsemblPlants; AT5G27740.1; AT5G27740.1; AT5G27740.
DR GeneID; 832836; -.
DR Gramene; AT5G27740.1; AT5G27740.1; AT5G27740.
DR KEGG; ath:AT5G27740; -.
DR TAIR; AT5G27740; -.
DR eggNOG; KOG2035; Eukaryota.
DR eggNOG; COG0470; LUCA.
DR HOGENOM; HOG000224153; -.
DR InParanoid; Q8VXX4; -.
DR KO; K10756; -.
DR OMA; QREFKVV; -.
DR OrthoDB; EOG09360GSB; -.
DR PhylomeDB; Q8VXX4; -.
DR Reactome; R-ATH-110312; Translesion synthesis by REV1.
DR Reactome; R-ATH-110314; Recognition of DNA damage by PCNA-containing replication complex.
DR Reactome; R-ATH-110320; Translesion Synthesis by POLH.
DR Reactome; R-ATH-174411; Polymerase switching on the C-strand of the telomere.
DR Reactome; R-ATH-5651801; PCNA-Dependent Long Patch Base Excision Repair.
DR Reactome; R-ATH-5655862; Translesion synthesis by POLK.
DR Reactome; R-ATH-5656121; Translesion synthesis by POLI.
DR Reactome; R-ATH-5656169; Termination of translesion DNA synthesis.
DR Reactome; R-ATH-5696397; Gap-filling DNA repair synthesis and ligation in GG-NER.
DR Reactome; R-ATH-5696400; Dual Incision in GG-NER.
DR Reactome; R-ATH-6782135; Dual incision in TC-NER.
DR Reactome; R-ATH-6782210; Gap-filling DNA repair synthesis and ligation in TC-NER.
DR Reactome; R-ATH-69091; Polymerase switching.
DR PRO; PR:Q8VXX4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR Genevisible; Q8VXX4; AT.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-dependent DNA replication; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Complete proteome; DNA replication; DNA-binding;
KW Nucleotide-binding; Nucleus; Reference proteome.
FT CHAIN 1 354 Replication factor C subunit 3.
FT /FTId=PRO_0000422631.
FT NP_BIND 41 48 ATP. {ECO:0000255}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 33 192 ismart:AAA [T]
SQ SEQUENCE 354 AA; 40600 MW; 26FFFA83ABEC43BF CRC64;
MLWVDKYRPK SLDKVIVHED IAQKLKKLVS EQDCPHLLFY GPSGSGKKTL IMALLKQIYG
ASAEKVKVEN RAWKVDAGSR TIDLELTTLS STNHVELTPS DAGFQDRYIV QEIIKEMAKN
RPIDTKGKKG YKVLVLNEVD KLSREAQHSL RRTMEKYSSS CRLILCCNSS SKVTEAIKSR
CLNVRINAPS QEEIVKVLEF VAKKESLQLP QGFAARIAEK SNRSLRRAIL SLETCRVQNY
PFTGNQVISP MDWEEYVAEI ATDMMKEQSP KKLFQVRGKV YELLVNCIPP EVILKRLLHE
LLKKLDSELK LEVCHWAAYY EHRMRLGQKA IFHIEAFVAK FMSIYKNFLI STFG
//
|
