Entry sw:PHOSP_PHODV

ID   PHOSP_PHODV             Reviewed;         507 AA.
AC   P35939;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   02-NOV-2016, entry version 62.
DE   RecName: Full=Phosphoprotein;
DE            Short=Protein P;
GN   Name=P/V;
OS   Phocine distemper virus (PDV).
OC   Viruses; ssRNA viruses; ssRNA negative-strand viruses;
OC   Mononegavirales; Paramyxoviridae; Morbillivirus.
OX   NCBI_TaxID=11240;
OH   NCBI_TaxID=9709; Phocidae (true seals).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Ulster/88;
RX   PubMed=1535099; DOI=10.1099/0022-1317-73-6-1587;
RA   Curran M.D., Rima B.K.;
RT   "The genes encoding the phospho- and matrix proteins of phocine
RT   distemper virus.";
RL   J. Gen. Virol. 73:1587-1591(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND RNA EDITING.
RC   STRAIN=Isolate DK88-4A;
RX   PubMed=1634877; DOI=10.1099/0022-1317-73-4-885;
RA   Blixenkrone-Moeller M., Sharma B., Varsanyi T., Hu A., Norrby E.,
RA   Koevamees J.;
RT   "Sequence analysis of the genes encoding the nucleocapsid protein and
RT   phosphoprotein (P) of phocid distemper virus, and editing of the P
RT   gene transcript.";
RL   J. Gen. Virol. 73:885-893(1992).
CC   -!- FUNCTION: Essential component of the RNA polymerase and the
CC       nascent chain assembly complex. Also required during RNA
CC       synthesis.
CC   -!- RNA EDITING: Modified_positions=231 {ECO:0000269|PubMed:1634877};
CC       Note=Partially edited. RNA editing at this position consists of an
CC       insertion of one guanine nucleotide. The sequence displayed here
CC       is the P protein, derived from the unedited RNA. The edited RNA
CC       version gives rise to the V protein (AC P35941).;
CC   -!- SIMILARITY: Belongs to the morbillivirus P protein family.
CC       {ECO:0000305}.
DR   EMBL; D10371; BAA01203.1; -; Genomic_RNA.
DR   EMBL; X75960; CAA53573.1; -; Genomic_RNA.
DR   PIR; JQ1609; JQ1563.
DR   ProteinModelPortal; P35939; -.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR   InterPro; IPR004897; P/V_Pprotein_paramyxoviral.
DR   InterPro; IPR028243; Paramyxo_P/V_N.
DR   InterPro; IPR016075; RNA_pol_Pprot-P_XD_paramyxovir.
DR   Pfam; PF03210; Paramyx_P_V_C; 1.
DR   Pfam; PF13825; Paramyxo_PNT; 1.
DR   SUPFAM; SSF101089; SSF101089; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; RNA editing; Viral RNA replication.
FT   CHAIN         1    507       Phosphoprotein.
FT                                /FTId=PRO_0000142698.
FT   CONFLICT    192    192       A -> T (in Ref. 2; CAA53573).
FT                                {ECO:0000305}.
FT   CONFLICT    224    224       A -> V (in Ref. 2; CAA53573).
FT                                {ECO:0000305}.
FT   CONFLICT    393    394       DV -> EL (in Ref. 2; CAA53573).
FT                                {ECO:0000305}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT       324    501       ipfam:Paramyx_P_V_C [T]
FT   MYHIT         4    312       ipfam:Paramyxo_PNT [T]
SQ   SEQUENCE   507 AA;  54691 MW;  D24BC3F3B86F712E CRC64;
     MAEEQAYHVS KGLECIKALR ENPPNMEEIQ EVSNIRDQTY KSSKESGTTG VQEEEITQNI
     DESHTPTKRS NSVSDVLQED QRGREDNTAP VEAKDRIEED TQTGPAVRRY YVYDHCGEKV
     KGIEDADSLM VPAGPPSNRG FEGREGSLDD SIEDSSEDYS EGNASSNWGY TFGLNPDRAA
     DVSMLMEEEL TALLGTGHNA GGQKRDGRTL QFPNSPEGSI GNQACEPIKK GTGEKLASHG
     MMTAAGLTNG ATRSAPKSTG GSSGPNASAG SVPQSVTTAK MIQKCKTESG TRPQPEKPNE
     IESDGEYDDE LFSEIQEIRS AITKLTEDNQ SILSKLDTLL LLKGEIDSIK KQISKQNIAI
     STIEGHLSSI MIAIPGFGKD TGDPTANVDI NPDVRPIIGR DSGRALAEVL KKPASSRGNQ
     KDGGLILGSK GQLLKDLQLK PIDKNSSSAI GFKPKDSAPS KAVIASLIRS SKVDQSHKQN
     MLSLLKNIKG DDNLNEFYQM IKSISHI
//