ID PHOSP_PHODV Reviewed; 507 AA.
AC P35939;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 02-NOV-2016, entry version 62.
DE RecName: Full=Phosphoprotein;
DE Short=Protein P;
GN Name=P/V;
OS Phocine distemper virus (PDV).
OC Viruses; ssRNA viruses; ssRNA negative-strand viruses;
OC Mononegavirales; Paramyxoviridae; Morbillivirus.
OX NCBI_TaxID=11240;
OH NCBI_TaxID=9709; Phocidae (true seals).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Ulster/88;
RX PubMed=1535099; DOI=10.1099/0022-1317-73-6-1587;
RA Curran M.D., Rima B.K.;
RT "The genes encoding the phospho- and matrix proteins of phocine
RT distemper virus.";
RL J. Gen. Virol. 73:1587-1591(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND RNA EDITING.
RC STRAIN=Isolate DK88-4A;
RX PubMed=1634877; DOI=10.1099/0022-1317-73-4-885;
RA Blixenkrone-Moeller M., Sharma B., Varsanyi T., Hu A., Norrby E.,
RA Koevamees J.;
RT "Sequence analysis of the genes encoding the nucleocapsid protein and
RT phosphoprotein (P) of phocid distemper virus, and editing of the P
RT gene transcript.";
RL J. Gen. Virol. 73:885-893(1992).
CC -!- FUNCTION: Essential component of the RNA polymerase and the
CC nascent chain assembly complex. Also required during RNA
CC synthesis.
CC -!- RNA EDITING: Modified_positions=231 {ECO:0000269|PubMed:1634877};
CC Note=Partially edited. RNA editing at this position consists of an
CC insertion of one guanine nucleotide. The sequence displayed here
CC is the P protein, derived from the unedited RNA. The edited RNA
CC version gives rise to the V protein (AC P35941).;
CC -!- SIMILARITY: Belongs to the morbillivirus P protein family.
CC {ECO:0000305}.
DR EMBL; D10371; BAA01203.1; -; Genomic_RNA.
DR EMBL; X75960; CAA53573.1; -; Genomic_RNA.
DR PIR; JQ1609; JQ1563.
DR ProteinModelPortal; P35939; -.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR InterPro; IPR004897; P/V_Pprotein_paramyxoviral.
DR InterPro; IPR028243; Paramyxo_P/V_N.
DR InterPro; IPR016075; RNA_pol_Pprot-P_XD_paramyxovir.
DR Pfam; PF03210; Paramyx_P_V_C; 1.
DR Pfam; PF13825; Paramyxo_PNT; 1.
DR SUPFAM; SSF101089; SSF101089; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; RNA editing; Viral RNA replication.
FT CHAIN 1 507 Phosphoprotein.
FT /FTId=PRO_0000142698.
FT CONFLICT 192 192 A -> T (in Ref. 2; CAA53573).
FT {ECO:0000305}.
FT CONFLICT 224 224 A -> V (in Ref. 2; CAA53573).
FT {ECO:0000305}.
FT CONFLICT 393 394 DV -> EL (in Ref. 2; CAA53573).
FT {ECO:0000305}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 324 501 ipfam:Paramyx_P_V_C [T]
FT MYHIT 4 312 ipfam:Paramyxo_PNT [T]
SQ SEQUENCE 507 AA; 54691 MW; D24BC3F3B86F712E CRC64;
MAEEQAYHVS KGLECIKALR ENPPNMEEIQ EVSNIRDQTY KSSKESGTTG VQEEEITQNI
DESHTPTKRS NSVSDVLQED QRGREDNTAP VEAKDRIEED TQTGPAVRRY YVYDHCGEKV
KGIEDADSLM VPAGPPSNRG FEGREGSLDD SIEDSSEDYS EGNASSNWGY TFGLNPDRAA
DVSMLMEEEL TALLGTGHNA GGQKRDGRTL QFPNSPEGSI GNQACEPIKK GTGEKLASHG
MMTAAGLTNG ATRSAPKSTG GSSGPNASAG SVPQSVTTAK MIQKCKTESG TRPQPEKPNE
IESDGEYDDE LFSEIQEIRS AITKLTEDNQ SILSKLDTLL LLKGEIDSIK KQISKQNIAI
STIEGHLSSI MIAIPGFGKD TGDPTANVDI NPDVRPIIGR DSGRALAEVL KKPASSRGNQ
KDGGLILGSK GQLLKDLQLK PIDKNSSSAI GFKPKDSAPS KAVIASLIRS SKVDQSHKQN
MLSLLKNIKG DDNLNEFYQM IKSISHI
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