MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Kynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_01969}; Short=KFA {ECO:0000255|HAMAP-Rule:MF_01969}; Short=KFase {ECO:0000255|HAMAP-Rule:MF_01969}; EC=3.5.1.9 {ECO:0000255|HAMAP-Rule:MF_01969}; AltName: Full=Arylformamidase {ECO:0000255|HAMAP-Rule:MF_01969}; AltName: Full=N-formylkynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_01969}; Short=FKF {ECO:0000255|HAMAP-Rule:MF_01969}; |
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| MyHits synonyms | KYNB_POLNA , A1VRN9 , 4F501DDF1F88186F |
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ID KYNB_POLNA Reviewed; 223 AA.
AC A1VRN9;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 02-NOV-2016, entry version 53.
DE RecName: Full=Kynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_01969};
DE Short=KFA {ECO:0000255|HAMAP-Rule:MF_01969};
DE Short=KFase {ECO:0000255|HAMAP-Rule:MF_01969};
DE EC=3.5.1.9 {ECO:0000255|HAMAP-Rule:MF_01969};
DE AltName: Full=Arylformamidase {ECO:0000255|HAMAP-Rule:MF_01969};
DE AltName: Full=N-formylkynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_01969};
DE Short=FKF {ECO:0000255|HAMAP-Rule:MF_01969};
GN Name=kynB {ECO:0000255|HAMAP-Rule:MF_01969};
GN OrderedLocusNames=Pnap_3018;
OS Polaromonas naphthalenivorans (strain CJ2).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=365044;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ2;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R.,
RA Brainard J., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Kim E., Madsen E.L., Richardson P.;
RT "Complete sequence of chromosome 1 of Polaromonas naphthalenivorans
RT CJ2.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-
CC kynurenine, the second step in the kynurenine pathway of
CC tryptophan degradation. {ECO:0000255|HAMAP-Rule:MF_01969}.
CC -!- CATALYTIC ACTIVITY: N-formyl-L-kynurenine + H(2)O = formate + L-
CC kynurenine. {ECO:0000255|HAMAP-Rule:MF_01969}.
CC -!- PATHWAY: Amino-acid degradation; L-tryptophan degradation via
CC kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
CC {ECO:0000255|HAMAP-Rule:MF_01969}.
CC -!- SIMILARITY: Belongs to the KynB family. {ECO:0000255|HAMAP-
CC Rule:MF_01969}.
DR EMBL; CP000529; ABM38317.1; -; Genomic_DNA.
DR RefSeq; WP_011802389.1; NC_008781.1.
DR ProteinModelPortal; A1VRN9; -.
DR STRING; 365044.Pnap_3018; -.
DR EnsemblBacteria; ABM38317; ABM38317; Pnap_3018.
DR KEGG; pna:Pnap_3018; -.
DR PATRIC; 22950739; VBIPolNap76733_3893.
DR eggNOG; ENOG4107VWA; Bacteria.
DR eggNOG; COG1878; LUCA.
DR HOGENOM; HOG000219455; -.
DR KO; K07130; -.
DR OMA; MDAHHRI; -.
DR OrthoDB; POG091H0N8N; -.
DR UniPathway; UPA00333; UER00454.
DR Proteomes; UP000000644; Chromosome.
DR GO; GO:0004061; F:arylformamidase activity; ISS:UniProtKB.
DR GO; GO:0004328; F:formamidase activity; IEA:InterPro.
DR GO; GO:0043420; P:anthranilate metabolic process; ISS:UniProtKB.
DR GO; GO:0019441; P:tryptophan catabolic process to kynurenine; ISS:UniProtKB.
DR HAMAP; MF_01969; KynB; 1.
DR InterPro; IPR007325; KFase.
DR InterPro; IPR017484; Kynurenine_formamidase_bac.
DR Pfam; PF04199; Cyclase; 1.
DR TIGRFAMs; TIGR03035; trp_arylform; 1.
PE 3: Inferred from homology;
KW Complete proteome; Hydrolase; Reference proteome;
KW Tryptophan catabolism.
FT CHAIN 1 223 Kynurenine formamidase.
FT /FTId=PRO_0000362126.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 22 165 ipfam:Cyclase [T]
FT MYHIT 19 222 ihamap:KynB [T]
SQ SEQUENCE 223 AA; 23917 MW; 4F501DDF1F88186F CRC64;
MTEPAAHFAS HAAAARTLRI WDISPPLDER SEVFPGDTAY SQELHFSLSP GCPVNVNRIT
LSPHTGAHAD APLHYASGEA AIGAVDLQPY LGPCRVIHCL DCGPLVEPAH IAHALENLPP
RVLLRTSRTA SQSWASFTAI APATLALLAT KNIVLIGIDT PSVDPAASQN LPSHQQLLRH
GLRVLENLVL DDVPEGDYEL IALPLKLMRA DASPVRAILR ELS
//
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