Entry sw:DF100_ARATH

ID   DF100_ARATH             Reviewed;          87 AA.
AC   Q3E6U0; A0MJT5; O49626;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   30-NOV-2016, entry version 60.
DE   RecName: Full=Defensin-like protein 100;
DE   Flags: Precursor;
GN   OrderedLocusNames=At4g22217; ORFNames=T10I14.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G.,
RA   Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N.,
RA   Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M.,
RA   Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M.,
RA   Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T.,
RA   Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I.,
RA   Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P.,
RA   Langham S.-A., McCullagh B., Bilham L., Robben J.,
RA   van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F.,
RA   Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
RA   Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P.,
RA   Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H.,
RA   De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R.,
RA   van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S.,
RA   Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R.,
RA   Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S.,
RA   Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H.,
RA   Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
RA   Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R.,
RA   Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S.,
RA   Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E.,
RA   Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A.,
RA   Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T.,
RA   Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C.,
RA   Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S.,
RA   Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K.,
RA   Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L.,
RA   Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J.,
RA   Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J.,
RA   Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D.,
RA   Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D.,
RA   Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C.,
RA   Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C.,
RA   Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R.,
RA   Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S.,
RA   Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A.,
RA   Chen E., Marra M.A., Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Resource (TAIR);
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17565583; DOI=10.1111/j.1365-313X.2007.03136.x;
RA   Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A.,
RA   Graham M.A., Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have
RT   been under-predicted in plants.";
RL   Plant J. 51:262-280(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in
RT   Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK27945.1; Type=Erroneous termination; Positions=88; Note=Translated as stop.; Evidence={ECO:0000305};
CC       Sequence=CAA16771.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 4 genes: At4g22210, At4g22212, At4g22214 and At4g22217.; Evidence={ECO:0000305};
CC       Sequence=CAB79176.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 4 genes: At4g22210, At4g22212, At4g22214 and At4g22217.; Evidence={ECO:0000305};
DR   EMBL; AL021712; CAA16771.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL161556; CAB79176.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002687; AEE84575.1; -; Genomic_DNA.
DR   EMBL; DQ446860; ABE66084.1; -; mRNA.
DR   EMBL; DQ912234; ABK27945.1; ALT_SEQ; mRNA.
DR   EMBL; EF182820; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; T04902; T04902.
DR   RefSeq; NP_567655.1; NM_118346.3.
DR   UniGene; At.54471; -.
DR   ProteinModelPortal; Q3E6U0; -.
DR   SMR; Q3E6U0; -.
DR   STRING; 3702.AT4G22217.1; -.
DR   PaxDb; Q3E6U0; -.
DR   EnsemblPlants; AT4G22217.1; AT4G22217.1; AT4G22217.
DR   GeneID; 828315; -.
DR   Gramene; AT4G22217.1; AT4G22217.1; AT4G22217.
DR   KEGG; ath:AT4G22217; -.
DR   TAIR; AT4G22217; -.
DR   HOGENOM; HOG000113304; -.
DR   OMA; CKESCIK; -.
DR   OrthoDB; EOG09361A2Q; -.
DR   PhylomeDB; Q3E6U0; -.
DR   PRO; PR:Q3E6U0; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
DR   InterPro; IPR020191; LMW_cysteine-rich.
DR   ProDom; PD032890; LMW_cysteine-rich; 1.
PE   3: Inferred from homology;
KW   Antimicrobial; Complete proteome; Disulfide bond; Fungicide;
KW   Plant defense; Reference proteome; Secreted; Signal.
FT   SIGNAL        1     29       {ECO:0000255}.
FT   CHAIN        30     87       Defensin-like protein 100.
FT                                /FTId=PRO_0000379663.
FT   DISULFID     31     79       {ECO:0000250}.
FT   DISULFID     38     64       {ECO:0000250}.
FT   DISULFID     44     76       {ECO:0000250}.
FT   DISULFID     48     78       {ECO:0000250}.
SQ   SEQUENCE   87 AA;  9695 MW;  8DED26A3BA180455 CRC64;
     MRSLRLRTVV VATIVVCLSV LLSPTEVDGS CDFPLGACTP FRDCKESCIK FKTRAGQTFF
     DGKCRPRDRP SVWTACFCCY YDSIGAQ
//