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DescriptionRecName: Full=Beta-defensin 103A; AltName: Full=Defensin, beta 103; AltName: Full=Defensin, beta 103A; Flags: Precursor;
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MyHits synonymsD103A_HORSE , Q0W9P9 , 8C327B78E71DD7B7
match map segment
ipfam:Defensin_beta  
Legends: 1, SIGNAL {ECO:0000250}; 2, PEPTIDE Beta-defensin 103A; 3, ipfam:Defensin_beta [T].
ID   D103A_HORSE             Reviewed;          67 AA.
AC   Q0W9P9;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   05-OCT-2016, entry version 50.
DE   RecName: Full=Beta-defensin 103A;
DE   AltName: Full=Defensin, beta 103;
DE   AltName: Full=Defensin, beta 103A;
DE   Flags: Precursor;
GN   Name=DEFB103A; Synonyms=DEFB103;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16723195; DOI=10.1016/j.gene.2006.03.006;
RA   Looft C., Paul S., Philipp U., Regenhard P., Kuiper H., Distl O.,
RA   Chowdhary B.P., Leeb T.;
RT   "Sequence analysis of a 212 kb defensin gene cluster on ECA 27q17.";
RL   Gene 376:192-198(2006).
CC   -!- FUNCTION: Exhibits antimicrobial activity against Gram-positive
CC       and Gram-negative bacteria. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the beta-defensin family. {ECO:0000305}.
DR   EMBL; AM039964; CAJ01801.1; -; Genomic_DNA.
DR   RefSeq; XP_003364293.1; XM_003364245.3.
DR   ProteinModelPortal; Q0W9P9; -.
DR   STRING; 9796.ENSECAP00000005162; -.
DR   PaxDb; Q0W9P9; -.
DR   Ensembl; ENSECAT00000007133; ENSECAP00000005162; ENSECAG00000007143.
DR   GeneID; 100629456; -.
DR   KEGG; ecb:100629456; -.
DR   eggNOG; ENOG410JFYR; Eukaryota.
DR   eggNOG; ENOG411134U; LUCA.
DR   GeneTree; ENSGT00530000064280; -.
DR   HOGENOM; HOG000015465; -.
DR   HOVERGEN; HBG004834; -.
DR   InParanoid; Q0W9P9; -.
DR   OMA; IRGGRCA; -.
DR   OrthoDB; EOG091G16TA; -.
DR   Proteomes; UP000002281; Chromosome 27.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042056; F:chemoattractant activity; IEA:Ensembl.
DR   GO; GO:0060326; P:cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR001855; Defensin_beta-typ.
DR   Pfam; PF00711; Defensin_beta; 1.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Complete proteome; Defensin;
KW   Disulfide bond; Reference proteome; Secreted; Signal.
FT   SIGNAL        1     22       {ECO:0000250}.
FT   PEPTIDE      23     67       Beta-defensin 103A.
FT                                /FTId=PRO_0000289806.
FT   DISULFID     33     62       {ECO:0000250}.
FT   DISULFID     40     55       {ECO:0000250}.
FT   DISULFID     45     63       {ECO:0000250}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        31     64       ipfam:Defensin_beta [T]
SQ   SEQUENCE   67 AA;  7545 MW;  8C327B78E71DD7B7 CRC64;
     MRIHFLLFAL LFLFLMPVPG NGGIINMLQK SYCKIRKGRC ALLGCLPKEE QIGSCSVSGR
     KCCRKKK
//