MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Thiosulfate-binding protein; Flags: Precursor; |
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| MyHits synonyms | CYSP_SALTY , P41031 , 3BB30B559122DAEF |
 Legends: 1, CONFLICT R -> L (in Ref. 1). {ECO:0000305}; 2, SIGNAL {ECO:0000250}; 3, CONFLICT SDV -> FDL (in Ref. 1). {ECO:0000305}; 4, ipat:PROK_SULFATE_BIND_1 [T]; 5, ipat:PROK_SULFATE_BIND_2 [T].
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ID CYSP_SALTY Reviewed; 338 AA.
AC P41031;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 2.
DT 30-NOV-2016, entry version 99.
DE RecName: Full=Thiosulfate-binding protein;
DE Flags: Precursor;
GN Name=cysP; OrderedLocusNames=STM2444;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1909324;
RA Hryniewicz M.M., Kredich N.M.;
RT "The cysP promoter of Salmonella typhimurium: characterization of two
RT binding sites for CysB protein, studies of in vivo transcription
RT initiation, and demonstration of the anti-inducer effects of
RT thiosulfate.";
RL J. Bacteriol. 173:5876-5886(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA Waterston R., Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Part of the ABC transporter complex CysAWTP
CC (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This
CC protein specifically binds thiosulfate and is involved in its
CC transmembrane transport (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC (CysA), two transmembrane proteins (CysT and CysW) and a solute-
CC binding protein (CysP). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- SIMILARITY: Belongs to the prokaryotic sulfate-binding protein
CC family. {ECO:0000305}.
DR EMBL; AE006468; AAL21338.1; -; Genomic_DNA.
DR RefSeq; NP_461379.1; NC_003197.1.
DR RefSeq; WP_000290275.1; NC_003197.1.
DR ProteinModelPortal; P41031; -.
DR STRING; 99287.STM2444; -.
DR PaxDb; P41031; -.
DR PRIDE; P41031; -.
DR EnsemblBacteria; AAL21338; AAL21338; STM2444.
DR GeneID; 1253966; -.
DR KEGG; stm:STM2444; -.
DR PATRIC; 32383519; VBISalEnt20916_2582.
DR eggNOG; ENOG4108J2H; Bacteria.
DR eggNOG; COG4150; LUCA.
DR HOGENOM; HOG000260057; -.
DR KO; K02048; -.
DR OMA; VDQSHAG; -.
DR PhylomeDB; P41031; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR GO; GO:0015419; F:ATPase-coupled sulfate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01005; PBP2_CysP; 1.
DR InterPro; IPR000957; Sulphate/thiosulphate-bd_CS.
DR InterPro; IPR005669; Thiosulph/SO4-bd.
DR PANTHER; PTHR30368; PTHR30368; 1.
DR TIGRFAMs; TIGR00971; 3a0106s03; 1.
DR PROSITE; PS00401; PROK_SULFATE_BIND_1; 1.
DR PROSITE; PS00757; PROK_SULFATE_BIND_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; Periplasm; Reference proteome; Signal;
KW Sulfate transport; Transport.
FT SIGNAL 1 25 {ECO:0000250}.
FT CHAIN 26 338 Thiosulfate-binding protein.
FT /FTId=PRO_0000031682.
FT CONFLICT 110 110 R -> L (in Ref. 1). {ECO:0000305}.
FT CONFLICT 143 145 SDV -> FDL (in Ref. 1). {ECO:0000305}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 53 65 ipat:PROK_SULFATE_BIND_1 [T]
FT MYHIT 151 159 ipat:PROK_SULFATE_BIND_2 [T]
SQ SEQUENCE 338 AA; 37583 MW; 3BB30B559122DAEF CRC64;
MAVNLLKKRP LTLAAMLLLA GQAQATELLN SSYDVSRELF AALNPPFEQQ WAKDNGGDKL
TIKQSHAGSS KQALAILQGL KADVVTYNQV TDVQILHDKG KLIPADWQSR LPNNSSPFYS
TMGFLVRKGN PKNIHDWSDL VRSDVKLIFP NPKTSGNARY TYLAAWGAAD NADGGDKAKT
EQFMTQFLKN VEVFDTGGRG ATTTFAERGL GDVLISFESE VNNIRKQYEA QGFEVVIPKT
NILAEFPVAW VDKNVQANGT EKAAKAYLNW LYSPQAQTII THYYYRVNNP EIMGKQADKF
PQTELFRVEE KFGSWPEVMK THFASGGELD KLLAAGRK
//
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