Entry sw:CRIM2_ARATH

ID   CRIM2_ARATH             Reviewed;         226 AA.
AC   F4I1G5; F4I1G6; Q8L813; Q8RXM0;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   30-NOV-2016, entry version 39.
DE   RecName: Full=Cold-regulated 413 inner membrane protein 2, chloroplastic;
DE            Short=AtCOR413-IM2;
DE   AltName: Full=Cold-regulated 413 thylakoid membrane 2;
DE            Short=AtCOR413-TM2;
DE   Flags: Precursor;
GN   Name=COR413IM2; Synonyms=COR314TM2, COR413TM2;
GN   OrderedLocusNames=At1g29390; ORFNames=F15D2.42;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Resource (TAIR);
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-226 (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12746512; DOI=10.1104/pp.102.015255;
RA   Breton G., Danyluk J., Charron J.-B.F., Sarhan F.;
RT   "Expression profiling and bioinformatic analyses of a novel stress-
RT   regulated multispanning transmembrane protein family from cereals and
RT   Arabidopsis.";
RL   Plant Physiol. 132:64-74(2003).
RN   [5]
RP   TRANSIT PEPTIDE CLEAVAGE SITE, SUBCELLULAR LOCATION, TOPOLOGY, AND
RP   INDUCTION BY COLD.
RX   PubMed=18643950; DOI=10.1111/j.1365-3040.2008.01854.x;
RA   Okawa K., Nakayama K., Kakizaki T., Yamashita T., Inaba T.;
RT   "Identification and characterization of Cor413im proteins as novel
RT   components of the chloroplast inner envelope.";
RL   Plant Cell Environ. 31:1470-1483(2008).
RN   [6]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE
RP   SCALE ANALYSIS].
RX   PubMed=18431481; DOI=10.1371/journal.pone.0001994;
RA   Zybailov B., Rutschow H., Friso G., Rudella A., Emanuelsson O.,
RA   Sun Q., van Wijk K.J.;
RT   "Sorting signals, N-terminal modifications and abundance of the
RT   chloroplast proteome.";
RL   PLoS ONE 3:E1994-E1994(2008).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:18643950}; Multi-
CC       pass membrane protein {ECO:0000269|PubMed:18431481,
CC       ECO:0000269|PubMed:18643950}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=F4I1G5-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=F4I1G5-2; Sequence=VSP_044490;
CC         Note=Derived from EST data. No experimental confirmation
CC         available.;
CC   -!- INDUCTION: Accumulates at low levels in response to cold
CC       treatment. {ECO:0000269|PubMed:18643950}.
CC   -!- SIMILARITY: Belongs to the Cold-regulated 413 protein family.
CC       {ECO:0000305}.
DR   EMBL; AC068667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE31079.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE31080.1; -; Genomic_DNA.
DR   EMBL; AY080813; AAL87293.1; -; mRNA.
DR   EMBL; AY123008; AAM67541.1; -; mRNA.
DR   RefSeq; NP_564327.1; NM_102678.3. [F4I1G5-1]
DR   RefSeq; NP_973936.1; NM_202207.1. [F4I1G5-2]
DR   UniGene; At.40751; -.
DR   ProteinModelPortal; F4I1G5; -.
DR   BioGrid; 25049; 12.
DR   IntAct; F4I1G5; 1.
DR   STRING; 3702.AT1G29390.1; -.
DR   PaxDb; F4I1G5; -.
DR   EnsemblPlants; AT1G29390.1; AT1G29390.1; AT1G29390. [F4I1G5-1]
DR   GeneID; 839814; -.
DR   Gramene; AT1G29390.1; AT1G29390.1; AT1G29390.
DR   KEGG; ath:AT1G29390; -.
DR   TAIR; AT1G29390; -.
DR   eggNOG; ENOG410IX87; Eukaryota.
DR   eggNOG; ENOG4111T1X; LUCA.
DR   HOGENOM; HOG000082566; -.
DR   InParanoid; F4I1G5; -.
DR   OMA; NLQWVCT; -.
DR   OrthoDB; EOG09360R7S; -.
DR   PRO; PR:F4I1G5; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   Genevisible; F4I1G5; AT.
DR   GO; GO:0009941; C:chloroplast envelope; IDA:TAIR.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.
DR   GO; GO:0031357; C:integral component of chloroplast inner membrane; IDA:TAIR.
DR   GO; GO:0070417; P:cellular response to cold; IEP:TAIR.
DR   GO; GO:0009631; P:cold acclimation; IMP:TAIR.
DR   InterPro; IPR008892; COR413.
DR   Pfam; PF05562; WCOR413; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Chloroplast; Complete proteome; Membrane;
KW   Plastid; Plastid inner membrane; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT       1     76       Chloroplast.
FT                                {ECO:0000305|PubMed:18643950}.
FT   CHAIN        77    226       Cold-regulated 413 inner membrane protein
FT                                2, chloroplastic.
FT                                /FTId=PRO_0000420445.
FT   TOPO_DOM     77     79       Stromal. {ECO:0000255}.
FT   TRANSMEM     80    100       Helical. {ECO:0000255}.
FT   TOPO_DOM    101    103       Chloroplast intermembrane. {ECO:0000255}.
FT   TRANSMEM    104    124       Helical. {ECO:0000255}.
FT   TOPO_DOM    125    129       Stromal. {ECO:0000255}.
FT   TRANSMEM    130    150       Helical. {ECO:0000255}.
FT   TOPO_DOM    151    152       Chloroplast intermembrane. {ECO:0000255}.
FT   TRANSMEM    153    173       Helical. {ECO:0000255}.
FT   TOPO_DOM    174    176       Stromal. {ECO:0000255}.
FT   TRANSMEM    177    197       Helical. {ECO:0000255}.
FT   TOPO_DOM    198    205       Chloroplast intermembrane. {ECO:0000255}.
FT   TRANSMEM    206    226       Helical. {ECO:0000255}.
FT   VAR_SEQ       1     47       MASLCLSSSRIVSLHHQKPFLALKLRPRPSNISGLGHSTSV
FT                                VCFNPL -> MLVG (in isoform 2).
FT                                {ECO:0000305}.
FT                                /FTId=VSP_044490.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        49    217       ipfam:WCOR413 [T]
SQ   SEQUENCE   226 AA;  24798 MW;  05FCF00E2CF4B439 CRC64;
     MASLCLSSSR IVSLHHQKPF LALKLRPRPS NISGLGHSTS VVCFNPLRLS ADRQRTATVS
     ARAEKRRKRG SSVVCYATPM LSVHNLQWIS TISCVALMFA RGTGIHKSFV VPLFALQAPM
     GIVSWMKGEY GIWAAFLALL TRLFFSFPVE LELPFIALLL VIVAPYQVMS IRGKQEGAIL
     SLAISCFLAF QHFSRAGTLQ KAFDQNSVLA TVAIIGVTVV SFLFLI
//