ID CLPX_CYAP8 Reviewed; 448 AA.
AC B7JW74;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 02-NOV-2016, entry version 56.
DE RecName: Full=ATP-dependent Clp protease ATP-binding subunit ClpX {ECO:0000255|HAMAP-Rule:MF_00175};
GN Name=clpX {ECO:0000255|HAMAP-Rule:MF_00175};
GN OrderedLocusNames=PCC8801_2923;
OS Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 /
OS RF-1)).
OC Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC Cyanothecaceae; Cyanothece.
OX NCBI_TaxID=41431;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 8801;
RX PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M.,
RA Min H., Sherman L.A., Pakrasi H.B.;
RT "Novel metabolic attributes of the genus Cyanothece, comprising a
RT group of unicellular nitrogen-fixing Cyanobacteria.";
RL MBio 2:E214-E214(2011).
CC -!- FUNCTION: ATP-dependent specificity component of the Clp protease.
CC It directs the protease to specific substrates. Can perform
CC chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-
CC Rule:MF_00175}.
CC -!- SUBUNIT: Component of the ClpX-ClpP complex. Forms a hexameric
CC ring that, in the presence of ATP, binds to fourteen ClpP subunits
CC assembled into a disk-like structure with a central cavity,
CC resembling the structure of eukaryotic proteasomes.
CC {ECO:0000255|HAMAP-Rule:MF_00175}.
CC -!- SIMILARITY: Belongs to the ClpX chaperone family.
CC {ECO:0000255|HAMAP-Rule:MF_00175}.
DR EMBL; CP001287; ACK66919.1; -; Genomic_DNA.
DR RefSeq; WP_012596185.1; NC_011726.1.
DR ProteinModelPortal; B7JW74; -.
DR SMR; B7JW74; -.
DR STRING; 41431.PCC8801_2923; -.
DR PRIDE; B7JW74; -.
DR EnsemblBacteria; ACK66919; ACK66919; PCC8801_2923.
DR KEGG; cyp:PCC8801_2923; -.
DR PATRIC; 21578168; VBICyaSp125535_3096.
DR eggNOG; ENOG4105CHN; Bacteria.
DR eggNOG; COG1219; LUCA.
DR HOGENOM; HOG000010093; -.
DR KO; K03544; -.
DR OMA; HYKRVQA; -.
DR OrthoDB; POG091H01U4; -.
DR Proteomes; UP000008204; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:UniProtKB-HAMAP.
DR Gene3D; 3.40.50.300; -; 2.
DR HAMAP; MF_00175; ClpX; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR004487; Clp_protease_ATP-bd_su_ClpX.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010603; Znf_CppX_C4.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR Pfam; PF06689; zf-C4_ClpX; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SMART; SM00994; zf-C4_ClpX; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00382; clpX; 1.
PE 3: Inferred from homology;
KW ATP-binding; Chaperone; Complete proteome; Metal-binding;
KW Nucleotide-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1 448 ATP-dependent Clp protease ATP-binding
FT subunit ClpX.
FT /FTId=PRO_1000189685.
FT ZN_FING 10 35 C4-type. {ECO:0000255|HAMAP-
FT Rule:MF_00175}.
FT NP_BIND 144 151 ATP. {ECO:0000255|HAMAP-Rule:MF_00175}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 341 437 ismart:ClpB_D2-small [T]
FT MYHIT 7 46 ismart:zf-C4_ClpX [T]
FT MYHIT 2 439 ihamap:ClpX [T]
FT MYHIT 135 334 ipfam:AAA_2 [T]
FT MYHIT 9 45 ipfam:zf-C4_ClpX [T]
FT MYHIT 341 418 ipfam:ClpB_D2-small [T]
FT MYHIT 135 288 ismart:AAA [T]
SQ SEQUENCE 448 AA; 49763 MW; 91E414AF386D486F CRC64;
MSKYDSHLKC SFCGKSQEQV RKLIAGPGVY ICDECVELCN EILDEELMDA PAAAVAGGGS
PKPDDSRPKR RPSRERLSFN QIPKPREIKK YLDEYVIGQD EAKKVLSVAV YNHYKRLSLA
SKPGEETSED HIELQKSNIL LMGPTGSGKT LLAQTLAQIL DVPFAVADAT TLTEAGYVGE
DVENILLRLL QVADLDVEEA QRGIIYIDEI DKIARKSENP SITRDVSGEG VQQALLKMLE
GTIANVPPQG GRKHPYQDCI QIDTSNILFI CGGAFVGLDK VIEQRRGKKS MGFIRPGDTN
QSKEKRAADL MQQAEPDDLV KFGMIPEFVG RIPVMASLEP LDEETLIAIL TQPRNALVKQ
YQKLLKMDNV QLEFNKDAVR AIAQEAYRRK TGARALRGIV EELMLDVMYE LPSRKDVQRC
LITKEMVEQR STADLLVHPS SLPTPESA
//
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