ID CC159_MOUSE Reviewed; 411 AA.
AC Q8C963; Q0VBB7; Q9CXZ5; Q9D4W5;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 02-NOV-2016, entry version 82.
DE RecName: Full=Coiled-coil domain-containing protein 159;
GN Name=Ccdc159;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3).
RC STRAIN=C57BL/6J; TISSUE=Cerebellum, Liver, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q8C963-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8C963-2; Sequence=VSP_033427;
CC Name=3;
CC IsoId=Q8C963-3; Sequence=VSP_033428, VSP_033429;
CC Note=No experimental confirmation available.;
DR EMBL; AK011114; BAB27409.1; -; mRNA.
DR EMBL; AK016073; BAB30102.1; -; mRNA.
DR EMBL; AK042884; BAC31391.1; -; mRNA.
DR EMBL; BC120702; AAI20703.1; -; mRNA.
DR EMBL; BC120704; AAI20705.1; -; mRNA.
DR CCDS; CCDS40557.1; -. [Q8C963-2]
DR CCDS; CCDS52738.1; -. [Q8C963-1]
DR RefSeq; NP_001158086.1; NM_001164614.1. [Q8C963-1]
DR RefSeq; NP_080253.2; NM_025977.3. [Q8C963-2]
DR UniGene; Mm.154305; -.
DR ProteinModelPortal; Q8C963; -.
DR SMR; Q8C963; -.
DR iPTMnet; Q8C963; -.
DR PhosphoSitePlus; Q8C963; -.
DR PaxDb; Q8C963; -.
DR PRIDE; Q8C963; -.
DR Ensembl; ENSMUST00000006403; ENSMUSP00000006403; ENSMUSG00000006241. [Q8C963-2]
DR Ensembl; ENSMUST00000170304; ENSMUSP00000126474; ENSMUSG00000006241. [Q8C963-1]
DR GeneID; 67119; -.
DR KEGG; mmu:67119; -.
DR UCSC; uc009omx.1; mouse. [Q8C963-2]
DR UCSC; uc009omy.2; mouse. [Q8C963-3]
DR UCSC; uc009omz.2; mouse. [Q8C963-1]
DR CTD; 126075; -.
DR MGI; MGI:1914369; Ccdc159.
DR eggNOG; ENOG410J016; Eukaryota.
DR eggNOG; ENOG41114KW; LUCA.
DR GeneTree; ENSGT00390000008201; -.
DR HOGENOM; HOG000139146; -.
DR HOVERGEN; HBG056552; -.
DR InParanoid; Q8C963; -.
DR OMA; WPETEEI; -.
DR OrthoDB; EOG091G0A8B; -.
DR PhylomeDB; Q8C963; -.
DR TreeFam; TF337495; -.
DR PRO; PR:Q8C963; -.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000006241; -.
DR Genevisible; Q8C963; MM.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Complete proteome;
KW Reference proteome.
FT CHAIN 1 411 Coiled-coil domain-containing protein
FT 159.
FT /FTId=PRO_0000332997.
FT COILED 269 305 {ECO:0000255}.
FT VAR_SEQ 1 12 MGEHERVVCCSS -> MNGC (in isoform 2).
FT {ECO:0000303|PubMed:15489334,
FT ECO:0000303|PubMed:16141072}.
FT /FTId=VSP_033427.
FT VAR_SEQ 263 267 SKKFL -> RGPGG (in isoform 3).
FT {ECO:0000303|PubMed:16141072}.
FT /FTId=VSP_033428.
FT VAR_SEQ 268 411 Missing (in isoform 3).
FT {ECO:0000303|PubMed:16141072}.
FT /FTId=VSP_033429.
FT CONFLICT 55 55 E -> D (in Ref. 1; BAB27409).
FT {ECO:0000305}.
SQ SEQUENCE 411 AA; 46342 MW; 8E9CA2940FC293AA CRC64;
MGEHERVVCC SSDSLLAGLS RDSDDCVSHL CTPPLLAITS WAAKERSQYS PPPGEPGPSS
DKALDCMTHW SRVLEPEIVN TASEQAGKSG AWEKEWDSEP QPHEGTPCSS SDVNKDHYHD
QDLVKRNHCV AKKSLEPSSA KVKVKNTMII PDSQKLLRCE LESLRSQLQA QSKAFEFLNH
SVTMLEKESC LQQIKIQQLE EVLSPTSRQG EKYGRKWSTE QELYGALAQG LQGLQKTLKE
GEELQRARTT RCLQLLAREI RDSKKFLWEE LELVREEVTF IYQKLQDQED EISENLLNIQ
KMQKTQVKCR KVLTKMKQQA YDSWPEAEGV PTEGNGCCKD DLQKELGDIW SAVHSLQSSI
DCLALSMGTR PRASSLRGQK GHQCKSSQCP SWDSDSDWER PFSKSGSYPP A
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