ID CAPD_RICCK Reviewed; 341 AA.
AC A8EZA9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 02-NOV-2016, entry version 56.
DE RecName: Full=UDP-glucose 4-epimerase;
DE EC=5.1.3.2;
DE AltName: Full=Galactowaldenase;
DE AltName: Full=UDP-galactose 4-epimerase;
GN Name=capD; OrderedLocusNames=A1E_03815;
OS Rickettsia canadensis (strain McKiel).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX NCBI_TaxID=293613;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=McKiel;
RA Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Dasch G., Eremeeva M.;
RT "Complete genome sequence of Rickettsia canadensis.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Epimerizes UDP-galactose to UDP-glucose. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY: UDP-alpha-D-glucose = UDP-alpha-D-galactose.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000305}.
DR EMBL; CP000409; ABV73692.1; -; Genomic_DNA.
DR RefSeq; WP_012148887.1; NC_009879.1.
DR ProteinModelPortal; A8EZA9; -.
DR STRING; 293613.A1E_03815; -.
DR EnsemblBacteria; ABV73692; ABV73692; A1E_03815.
DR KEGG; rcm:A1E_03815; -.
DR PATRIC; 17886219; VBIRicCan89738_0816.
DR eggNOG; ENOG4105C5E; Bacteria.
DR eggNOG; COG1086; LUCA.
DR HOGENOM; HOG000257079; -.
DR KO; K17716; -.
DR OMA; CIRTNID; -.
DR OrthoDB; POG091H0NB6; -.
DR Proteomes; UP000007056; Chromosome.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; -; 1.
DR InterPro; IPR013692; CapD_C.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR003869; Polysac_CapD-like.
DR Pfam; PF08485; Polysacc_syn_2C; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW Complete proteome; Isomerase; Lipopolysaccharide biosynthesis.
FT CHAIN 1 341 UDP-glucose 4-epimerase.
FT /FTId=PRO_0000314602.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 7 285 ipfam:Polysacc_synt_2 [T]
FT MYHIT 288 335 ipfam:Polysacc_syn_2C [T]
SQ SEQUENCE 341 AA; 38349 MW; B57C62589A32EA08 CRC64;
MFVDKTLMIT GGTGSFGNAV LSRFIESDII NDIKEIRIFS RDEKKQEDMR IALSNPKLKF
YIGDVRNYKS VDEAMHGVDY VFHAAALKQV PTCEFYPMEA INTNVLGAEN VLSAAIKNKV
AKVVVLSTDK AVYPVNVMGL SKALMEKLAI AKARMRSMNE TVLCVTRYGN VMASRGSVIP
LFINQIKQGK ELTITEPSMT RFLMSLVDSV NLVLYAFEHG RQGDIFVQKS PASTIAVLAK
ALQDIFGSKN KIRFIGTRHG EKHYESLVSS EDMAKAEDLG DYYRIPMDGR DLNYAKYFVE
GEKKVALLDD YTSHNTRRLN LEEVKELLLT LNYVQEELKN A
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