Entry sw:BH047_ARATH

ID   BH047_ARATH             Reviewed;         240 AA.
AC   Q9SN74;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   30-NOV-2016, entry version 103.
DE   RecName: Full=Transcription factor bHLH47;
DE   AltName: Full=Basic helix-loop-helix protein 47;
DE            Short=AtbHLH47;
DE            Short=bHLH 47;
DE   AltName: Full=Protein POPEYE;
DE   AltName: Full=Transcription factor EN 139;
DE   AltName: Full=bHLH transcription factor bHLH047;
GN   Name=BHLH47; Synonyms=EN139, PYE; OrderedLocusNames=At3g47640;
GN   ORFNames=F1P2.190;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M.,
RA   Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B.,
RA   Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P.,
RA   De Simone V., Choisne N., Artiguenave F., Robert C., Brottier P.,
RA   Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V.,
RA   Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S.,
RA   Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G.,
RA   Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B.,
RA   Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G.,
RA   Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J.,
RA   Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D.,
RA   Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D.,
RA   Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W.,
RA   Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J.,
RA   Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P.,
RA   Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S.,
RA   Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V.,
RA   Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C.,
RA   Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E.,
RA   Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A.,
RA   Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Resource (TAIR);
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 36-240, TISSUE SPECIFICITY, GENE FAMILY,
RP   AND NOMENCLATURE.
RC   STRAIN=cv. Columbia;
RX   PubMed=12679534; DOI=10.1093/molbev/msg088;
RA   Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT   "The basic helix-loop-helix transcription factor family in plants: a
RT   genome-wide study of protein structure and functional diversity.";
RL   Mol. Biol. Evol. 20:735-747(2003).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=12897250; DOI=10.1105/tpc.013839;
RA   Toledo-Ortiz G., Huq E., Quail P.H.;
RT   "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL   Plant Cell 15:1749-1770(2003).
RN   [6]
RP   SUBCELLULAR LOCATION, AND INTERACTION WITH BHLH115; BHLH104 AND ILR3.
RC   STRAIN=cv. Columbia;
RX   PubMed=25452667; DOI=10.1104/pp.114.250837;
RA   Selote D., Samira R., Matthiadis A., Gillikin J.W., Long T.A.;
RT   "Iron-binding E3 ligase mediates iron response in plants by targeting
RT   basic helix-loop-helix transcription factors.";
RL   Plant Physiol. 167:273-286(2015).
CC   -!- SUBUNIT: Homodimer (Probable). Forms heterodimer with PYEL
CC       proteins bHLH115, bHLH104 and ILR3 (PubMed:25452667).
CC       {ECO:0000269|PubMed:25452667, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
CC       ProRule:PRU00981, ECO:0000269|PubMed:25452667}.
CC   -!- TISSUE SPECIFICITY: Expressed constitutively in roots, leaves,
CC       stems, and flowers. {ECO:0000269|PubMed:12679534}.
CC   -!- SIMILARITY: Contains 1 bHLH (basic helix-loop-helix) domain.
CC       {ECO:0000255|PROSITE-ProRule:PRU00981}.
DR   EMBL; AY080786; AAL87269.1; -; mRNA.
DR   EMBL; AY114018; AAM45066.1; -; mRNA.
DR   EMBL; AL132955; CAB61990.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE78311.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE78312.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE78313.1; -; Genomic_DNA.
DR   EMBL; AF488582; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; T45724; T45724.
DR   RefSeq; NP_001190029.1; NM_001203100.1.
DR   RefSeq; NP_001190030.1; NM_001203101.1.
DR   RefSeq; NP_190348.1; NM_114632.4.
DR   UniGene; At.43911; -.
DR   ProteinModelPortal; Q9SN74; -.
DR   BioGrid; 9238; 15.
DR   IntAct; Q9SN74; 11.
DR   STRING; 3702.AT3G47640.1; -.
DR   PaxDb; Q9SN74; -.
DR   PRIDE; Q9SN74; -.
DR   EnsemblPlants; AT3G47640.1; AT3G47640.1; AT3G47640.
DR   EnsemblPlants; AT3G47640.2; AT3G47640.2; AT3G47640.
DR   EnsemblPlants; AT3G47640.3; AT3G47640.3; AT3G47640.
DR   GeneID; 823918; -.
DR   Gramene; AT3G47640.1; AT3G47640.1; AT3G47640.
DR   Gramene; AT3G47640.2; AT3G47640.2; AT3G47640.
DR   Gramene; AT3G47640.3; AT3G47640.3; AT3G47640.
DR   KEGG; ath:AT3G47640; -.
DR   TAIR; AT3G47640; -.
DR   eggNOG; ENOG410J050; Eukaryota.
DR   eggNOG; ENOG410YN73; LUCA.
DR   HOGENOM; HOG000070871; -.
DR   InParanoid; Q9SN74; -.
DR   OMA; ILCEATR; -.
DR   OrthoDB; EOG09360LGT; -.
DR   PhylomeDB; Q9SN74; -.
DR   PRO; PR:Q9SN74; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   Genevisible; Q9SN74; AT.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IDA:TAIR.
DR   GO; GO:0010106; P:cellular response to iron ion starvation; IMP:TAIR.
DR   GO; GO:0055072; P:iron ion homeostasis; IMP:TAIR.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Complete proteome; DNA-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN         1    240       Transcription factor bHLH47.
FT                                /FTId=PRO_0000358745.
FT   DOMAIN       27     77       bHLH. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00981}.
FT   COILED       98    131       {ECO:0000255}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        27     77       iprf:BHLH [T]
SQ   SEQUENCE   240 AA;  26944 MW;  2D2D8BCB54C27822 CRC64;
     MVSKTPSTSS DEANATADER CRKGKVPKRI NKAVRERLKR EHLNELFIEL ADTLELNQQN
     SGKASILCEA TRFLKDVFGQ IESLRKEHAS LLSESSYVTT EKNELKEETS VLETEISKLQ
     NEIEARANQS KPDLNTSPAP EYHHHHYQQQ HPERVSQFPG LPIFQGPGFQ QSATTLHPPA
     TVLVLPIQPD PQTQDISEMT QAQQPLMFNS SNVSKPCPRY ASAADSWSSR LLGERLKASE
//