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Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7

DescriptionRecName: Full=Protein AmpE;
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MyHits synonymsAMPE_SHIFL , P0AE15 , P13017 , C92C05B2DFE0D6AD
match map segment
ipfam:AmpE  
Legends: 1, TOPO_DOM Periplasmic. {ECO:0000255}; 2, TRANSMEM Helical. {ECO:0000255}; 3, TOPO_DOM Cytoplasmic. {ECO:0000255}. 
ID   AMPE_SHIFL              Reviewed;         284 AA.
AC   P0AE15; P13017;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   02-NOV-2016, entry version 61.
DE   RecName: Full=Protein AmpE;
GN   Name=ampE; OrderedLocusNames=SF0108, S0110;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H.,
RA   Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J.,
RA   Sun L., Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S.,
RA   Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y.,
RA   Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/IAI.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W.,
RA   Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A.,
RA   Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S.,
RA   Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella
RT   flexneri serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Putative signaling protein in beta-lactamase regulation.
CC       AmpE seems not to act as a direct sensor for beta-lactams (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
DR   EMBL; AE005674; AAN41772.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP15653.1; -; Genomic_DNA.
DR   RefSeq; NP_706065.2; NC_004337.2.
DR   RefSeq; WP_000172005.1; NZ_LVJC01000012.1.
DR   ProteinModelPortal; P0AE15; -.
DR   STRING; 198214.SF0108; -.
DR   PaxDb; P0AE15; -.
DR   PRIDE; P0AE15; -.
DR   EnsemblBacteria; AAN41772; AAN41772; SF0108.
DR   EnsemblBacteria; AAP15653; AAP15653; S0110.
DR   GeneID; 1027516; -.
DR   KEGG; sfl:SF0108; -.
DR   KEGG; sft:NCTC1_00108; -.
DR   KEGG; sfx:S0110; -.
DR   PATRIC; 18701158; VBIShiFle31049_0121.
DR   eggNOG; ENOG4106A72; Bacteria.
DR   eggNOG; COG3725; LUCA.
DR   HOGENOM; HOG000116788; -.
DR   KO; K03807; -.
DR   OMA; HFSRALP; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031347; AmpE.
DR   Pfam; PF17113; AmpE; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN         1    284       Protein AmpE.
FT                                /FTId=PRO_0000064593.
FT   TOPO_DOM      1     43       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     44     60       Helical. {ECO:0000255}.
FT   TOPO_DOM     61     67       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     68     84       Helical. {ECO:0000255}.
FT   TOPO_DOM     85    194       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    195    211       Helical. {ECO:0000255}.
FT   TOPO_DOM    212    267       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    268    284       Helical. {ECO:0000255}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT         1    284       ipfam:AmpE [T]
SQ   SEQUENCE   284 AA;  32122 MW;  C92C05B2DFE0D6AD CRC64;
     MTLFTTLLVL IFERLFKLGE HWQLDHRLEA FFRRVKHFSL GRTLGMTIIA MGVTFLLLRA
     LQGVLFNVPT LLVWLLIGLL CIGAGKVRLH YHAYLTAASR NDSHARATMA GELTMIHGVP
     AGCDEREYLR ELQNALLWIN FRFYLAPLFW LIVGGTWGPV TLMGYAFLRA WQYWLARYQT
     PHHRLQSGID AVLHVLDWVP VRLAGVVYAL IGHGEKALPA WFASLGDFHT SQYQVLTRLA
     QFSLAREPHV DKVETPKAAV SMAKKTSFVV VVVIALLTIY GALV
//