MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Acid tolerance regulatory protein ActR; |
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| MyHits synonyms | ACTR_SINMW , A6UEL7 , Q52913 , 9BD60917F815CB4D |
 Legends: 1, 4-aspartylphosphate. {ECO:0000255|PROSITE-ProRule:PRU00169}.
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ID ACTR_SINMW Reviewed; 194 AA.
AC A6UEL7; Q52913;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 02-NOV-2016, entry version 63.
DE RecName: Full=Acid tolerance regulatory protein ActR;
GN Name=actR; OrderedLocusNames=Smed_3273;
OS Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=366394;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8757734; DOI=10.1099/13500872-142-7-1693;
RA Tiwari R.P., Reeve W.G., Dilworth M.J., Glenn A.R.;
RT "Acid tolerance in Rhizobium meliloti strain WSM419 involves a two-
RT component sensor-regulator system.";
RL Microbiology 142:1693-1704(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Reeve W.G., Richardson P.;
RT "Complete sequence of Sinorhizobium medicae WSM419 chromosome.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Member of the two-component regulatory system ActS/ActR
CC acting in acid tolerance. These data implicate that a two-
CC component sensor may be involved in pH sensing and/or response.
CC -!- PTM: Phosphorylated by ActS. {ECO:0000305}.
CC -!- SIMILARITY: Contains 1 response regulatory domain.
CC {ECO:0000255|PROSITE-ProRule:PRU00169}.
DR EMBL; L39938; AAB38421.2; -; Genomic_DNA.
DR EMBL; CP000738; ABR62097.1; -; Genomic_DNA.
DR RefSeq; WP_012067478.1; NC_009636.1.
DR RefSeq; YP_001328932.1; NC_009636.1.
DR ProteinModelPortal; A6UEL7; -.
DR STRING; 366394.Smed_3273; -.
DR EnsemblBacteria; ABR62097; ABR62097; Smed_3273.
DR GeneID; 5324152; -.
DR KEGG; smd:Smed_3273; -.
DR PATRIC; 23625793; VBISinMed134228_6514.
DR eggNOG; ENOG4108UYB; Bacteria.
DR eggNOG; COG4567; LUCA.
DR HOGENOM; HOG000034817; -.
DR KO; K15012; -.
DR OMA; AIRQRRD; -.
DR OrthoDB; POG091H1BVE; -.
DR Proteomes; UP000001108; Chromosome.
DR GO; GO:0005622; C:intracellular; IEA:GOC.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.60; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeodomain-like.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Complete proteome; DNA-binding; Phosphoprotein; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1 194 Acid tolerance regulatory protein ActR.
FT /FTId=PRO_0000310444.
FT DOMAIN 24 138 Response regulatory.
FT {ECO:0000255|PROSITE-ProRule:PRU00169}.
FT MOD_RES 73 73 4-aspartylphosphate.
FT {ECO:0000255|PROSITE-ProRule:PRU00169}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 23 134 ismart:REC [T]
FT MYHIT 24 138 iprf:RESPONSE_REGULATORY [T]
FT MYHIT 26 134 ipfam:Response_reg [T]
FT MYHIT 158 186 ipfam:HTH_8 [T]
SQ SEQUENCE 194 AA; 21421 MW; 9BD60917F815CB4D CRC64;
MIEKSTPAPI THAADADLIG PDKSLLIVDD DTAFLRRLAR AMEARGFAVE IAESVAEGIA
KAKTRPPKHA VIDLRLGDGS GLDVIEAIRG RRDDTRMIVL TGYGNIATAV NAVKLGALDY
LAKPADADDI LAALIQRPGE RVEPPENPMS ADRVRWEHIQ RVYEMCERNV SETARRLNMH
RRTLQRILAK RAPK
//
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