ID Q6GMH1_DANRE Unreviewed; 496 AA.
AC Q6GMH1;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 10-MAY-2017, entry version 111.
DE SubName: Full=Drebrin-like a {ECO:0000313|Ensembl:ENSDARP00000026512};
DE SubName: Full=Zgc:91835 {ECO:0000313|EMBL:AAH74079.1};
GN Name=dbnla {ECO:0000313|Ensembl:ENSDARP00000026512,
GN ECO:0000313|ZFIN:ZDB-GENE-040704-42};
GN Synonyms=zgc:91835 {ECO:0000313|EMBL:AAH74079.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH74079.1};
RN [1] {ECO:0000313|EMBL:AAH74079.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH74079.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000026512}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000026512};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000026512, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000026512,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
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DR EMBL; CT826389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC074079; AAH74079.1; -; mRNA.
DR RefSeq; NP_001002201.1; NM_001002201.1.
DR UniGene; Dr.76820; -.
DR STRING; 7955.ENSDARP00000026512; -.
DR Ensembl; ENSDART00000025691; ENSDARP00000026512; ENSDARG00000008170.
DR GeneID; 431748; -.
DR KEGG; dre:431748; -.
DR CTD; 431748; -.
DR ZFIN; ZDB-GENE-040704-42; dbnla.
DR eggNOG; KOG3655; Eukaryota.
DR eggNOG; ENOG410XRVX; LUCA.
DR GeneTree; ENSGT00530000062953; -.
DR HOGENOM; HOG000008567; -.
DR HOVERGEN; HBG051316; -.
DR KO; K20520; -.
DR TreeFam; TF318935; -.
DR Reactome; R-DRE-264870; Caspase-mediated cleavage of cytoskeletal proteins.
DR Reactome; R-DRE-6794361; Interactions of neurexins and neuroligins at synapses.
DR Reactome; R-DRE-6798695; Neutrophil degranulation.
DR Proteomes; UP000000437; Chromosome 10.
DR Bgee; ENSDARG00000008170; -.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0048812; P:neuron projection morphogenesis; IEA:InterPro.
DR GO; GO:0006898; P:receptor-mediated endocytosis; IEA:InterPro.
DR GO; GO:0097178; P:ruffle assembly; IEA:InterPro.
DR GO; GO:0007416; P:synapse assembly; IEA:InterPro.
DR Gene3D; 3.40.20.10; -; 1.
DR InterPro; IPR002108; ADF-H.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom.
DR InterPro; IPR029923; Dbnl.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10829:SF30; PTHR10829:SF30; 1.
DR Pfam; PF00241; Cofilin_ADF; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00102; ADF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SSF50044; 1.
DR PROSITE; PS51263; ADF_H; 1.
DR PROSITE; PS50002; SH3; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Proteomics identification {ECO:0000213|PeptideAtlas:Q6GMH1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 2 131 ADF-H. {ECO:0000259|PROSITE:PS51263}.
FT DOMAIN 438 496 SH3. {ECO:0000259|PROSITE:PS50002}.
FT COILED 179 257 {ECO:0000256|SAM:Coils}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 438 496 iprf:SH3 [T]
FT MYHIT 441 496 ismart:SH3 [T]
FT MYHIT 10 131 ismart:ADF [T]
FT MYHIT 445 494 ipfam:SH3_9 [T]
FT MYHIT 13 129 ipfam:Cofilin_ADF [T]
FT MYHIT 2 131 iprf:ADF_H [T]
SQ SEQUENCE 496 AA; 55889 MW; 10084C9F96A7DEF2 CRC64;
MAVNLSKNGP ALTEAYDEVV SGKKDWVLFT YEGNSNDIRV AGKGDGGLEE MVDELNSGKV
MYAFCRVLDP SSGVPKFVLI NWTGEGVKDL RKGVCARHVH SMANFLRGAH VTINARSDDD
VEPAAIMEKV AKGSGVNYNI HRESSQNNHS EPPGRVGSVY KKVSALDEIQ GTSRDNFWAQ
AERDEKNRRQ EERRKADEER QRLEKERRDQ ESREAEERER RRKEREKEID QQRIFEKKLE
AENKEEEQRK LEKEQQQTPV KAGILRSASV QKANEAASII SQRSTNPREL FMKKERSLVN
DATSSPSSSR QGQLRSPFLS QQAVSTPSES RSQPLSPLQP VASVSHVPAK VSPVRETQTF
PVKTADPFSD DPFVSEQAED YDDEWDDSDA EVSSPAATHK QNADGNSTYM NIPSNQSLYE
NVHQDFQSPA DEEENGDNQN ICARALYDYQ ASDDTEISFD PDDVISGIDM IDEGWWRGYG
PDGHYGMFPA NYVELM
//
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