ID ZN672_MOUSE Reviewed; 468 AA.
AC Q99LH4; Q8BIR7;
DT 02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 10-MAY-2017, entry version 123.
DE RecName: Full=Zinc finger protein 672;
GN Name=Znf672; Synonyms=Zfp672;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo, Lung, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II, and FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; AK029711; BAC26575.1; -; mRNA.
DR EMBL; AK035113; BAC28948.1; -; mRNA.
DR EMBL; AK085166; BAC39380.1; -; mRNA.
DR EMBL; AL845463; CAI25445.1; -; Genomic_DNA.
DR EMBL; BC003258; AAH03258.1; -; mRNA.
DR EMBL; BC034706; AAH34706.1; -; mRNA.
DR CCDS; CCDS24727.1; -.
DR RefSeq; NP_001243445.1; NM_001256516.1.
DR RefSeq; NP_001243446.1; NM_001256517.1.
DR RefSeq; NP_001243447.1; NM_001256518.1.
DR RefSeq; NP_001243448.1; NM_001256519.1.
DR RefSeq; NP_001243449.1; NM_001256520.1.
DR RefSeq; NP_848876.2; NM_178761.5.
DR RefSeq; XP_006533583.1; XM_006533520.3.
DR RefSeq; XP_011247371.1; XM_011249069.2.
DR RefSeq; XP_017170079.1; XM_017314590.1.
DR RefSeq; XP_017170080.1; XM_017314591.1.
DR UniGene; Mm.72124; -.
DR ProteinModelPortal; Q99LH4; -.
DR SMR; Q99LH4; -.
DR STRING; 10090.ENSMUSP00000060088; -.
DR PhosphoSitePlus; Q99LH4; -.
DR MaxQB; Q99LH4; -.
DR PaxDb; Q99LH4; -.
DR PeptideAtlas; Q99LH4; -.
DR PRIDE; Q99LH4; -.
DR Ensembl; ENSMUST00000057836; ENSMUSP00000060088; ENSMUSG00000049755.
DR Ensembl; ENSMUST00000064786; ENSMUSP00000070567; ENSMUSG00000049755.
DR Ensembl; ENSMUST00000108829; ENSMUSP00000104457; ENSMUSG00000049755.
DR GeneID; 319475; -.
DR KEGG; mmu:319475; -.
DR UCSC; uc007jaz.2; mouse.
DR CTD; 319475; -.
DR MGI; MGI:2442105; Zfp672.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00730000111556; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR InParanoid; Q99LH4; -.
DR OMA; HQGERPH; -.
DR OrthoDB; EOG091G02KC; -.
DR PhylomeDB; Q99LH4; -.
DR TreeFam; TF337999; -.
DR PRO; PR:Q99LH4; -.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000049755; -.
DR CleanEx; MM_ZFP672; -.
DR ExpressionAtlas; Q99LH4; baseline and differential.
DR Genevisible; Q99LH4; MM.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; SSF57667; 8.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 2: Evidence at transcript level;
KW Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1 468 Zinc finger protein 672.
FT /FTId=PRO_0000233992.
FT ZN_FING 15 37 C2H2-type 1. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 43 65 C2H2-type 2. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 71 93 C2H2-type 3. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 100 123 C2H2-type 4. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 129 151 C2H2-type 5; degenerate.
FT {ECO:0000255|PROSITE-ProRule:PRU00042}.
FT ZN_FING 167 189 C2H2-type 6. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 202 224 C2H2-type 7. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 230 252 C2H2-type 8. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 258 280 C2H2-type 9. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 286 308 C2H2-type 10. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 314 336 C2H2-type 11. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 342 364 C2H2-type 12. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 370 392 C2H2-type 13. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 398 420 C2H2-type 14. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT CONFLICT 306 306 R -> H (in Ref. 1; BAC26575).
FT {ECO:0000305}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 43 65 ismart:ZnF_C2H2 [T]
FT MYHIT 400 420 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 15 42 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 286 313 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 43 70 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 258 280 ismart:ZnF_C2H2 [T]
FT MYHIT 316 336 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 202 224 ismart:ZnF_C2H2 [T]
FT MYHIT 258 285 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 314 341 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 167 189 ismart:ZnF_C2H2 [T]
FT MYHIT 370 397 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 230 257 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 344 364 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 73 93 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 100 128 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 71 93 ismart:ZnF_C2H2 [T]
FT MYHIT 17 37 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 230 252 ismart:ZnF_C2H2 [T]
FT MYHIT 129 151 ismart:ZnF_C2H2 [T]
FT MYHIT 314 336 ismart:ZnF_C2H2 [T]
FT MYHIT 204 224 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 167 189 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 342 364 ismart:ZnF_C2H2 [T]
FT MYHIT 202 229 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 260 280 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 286 308 ismart:ZnF_C2H2 [T]
FT MYHIT 71 98 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 100 123 ismart:ZnF_C2H2 [T]
FT MYHIT 370 392 ismart:ZnF_C2H2 [T]
FT MYHIT 15 37 ismart:ZnF_C2H2 [T]
FT MYHIT 44 65 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 288 308 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 372 392 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 342 369 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 169 189 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 232 252 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 398 420 ismart:ZnF_C2H2 [T]
FT MYHIT 102 123 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 398 425 iprf:ZINC_FINGER_C2H2_2 [T]
SQ SEQUENCE 468 AA; 52154 MW; 110623DEE3A39C1D CRC64;
MFTAPGMATT QERPYSCSVC GKSFQYSAVL LRHERAHGGD KRFCCLECGE RCARAADLRA
HRWTHAGQTL YICSECGQSF SHSGLLDLHL GTHRRRSRTR PCRLCGRRFP HVPALLLHRA
RQHPPEKPHR CPLCARSFRQ SALPFHLARA HPPEIITVTA PSPSTLYHCT QCPRAFHSSA
GLRNHSRIHV VPSLSDPGTE AHLCGICGKS FSKSSTLTRH LQRHSGEKPF KCPECGKGFL
ESATLVRHQR THTGEKPYAC SDCGRCFSES STLLRHQRSH QGERPHVCAT CGKGFGQRYD
LVVHQRSHTG ERPFPCPQCG RGFTDRSDLT KHLRTHTGEK PYHCELCGKR FTCISNLNVH
LRNHAGHKPH KCPECGKSFS VASKLALHRK THLGERTAEC TECGKFFSHG RSLSQHQRSH
RRARAAAMAA TTTTTVVTEV TIGPSLTLTG PTEQEKSGLL VSPFQETC
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