Legends: 1, ZN_FING C2H2-type 1. {ECO:0000255|PROSITE- ProRule:PRU00042}; 2, ZN_FING C2H2-type 2. {ECO:0000255|PROSITE- ProRule:PRU00042}; 3, ZN_FING C2H2-type 3. {ECO:0000255|PROSITE- ProRule:PRU00042}; 4, ZN_FING C2H2-type 4. {ECO:0000255|PROSITE- ProRule:PRU00042}; 5, ZN_FING C2H2-type 5. {ECO:0000255|PROSITE- ProRule:PRU00042}; 6, ZN_FING C2H2-type 6. {ECO:0000255|PROSITE- ProRule:PRU00042}; 7, ZN_FING C2H2-type 7. {ECO:0000255|PROSITE- ProRule:PRU00042}; 8, ZN_FING C2H2-type 8. {ECO:0000255|PROSITE- ProRule:PRU00042}; 9, ZN_FING C2H2-type 9. {ECO:0000255|PROSITE- ProRule:PRU00042}; 10, ZN_FING C2H2-type 10. {ECO:0000255|PROSITE- ProRule:PRU00042}; 11, ZN_FING C2H2-type 11. {ECO:0000255|PROSITE- ProRule:PRU00042}; 12, ZN_FING C2H2-type 12. {ECO:0000255|PROSITE- ProRule:PRU00042}; 13, ZN_FING C2H2-type 13. {ECO:0000255|PROSITE- ProRule:PRU00042}; 14, ZN_FING C2H2-type 14. {ECO:0000255|PROSITE- ProRule:PRU00042}; 15, ZN_FING C2H2-type 15; degenerate. {ECO:0000255|PROSITE-ProRule:PRU00042}; 16, ZN_FING C2H2-type 16. {ECO:0000255|PROSITE- ProRule:PRU00042}; 17, ZN_FING C2H2-type 17. {ECO:0000255|PROSITE- ProRule:PRU00042}; 18, ZN_FING C2H2-type 18. {ECO:0000255|PROSITE- ProRule:PRU00042}; 19, ZN_FING C2H2-type 19. {ECO:0000255|PROSITE- ProRule:PRU00042}; 20, ZN_FING C2H2-type 20. {ECO:0000255|PROSITE- ProRule:PRU00042}; 21, COMPBIAS Poly-Gly; 22, ipat:ZINC_FINGER_C2H2_1 [T]; 23, ismart:ZnF_C2H2 [T]; 24, iprf:ZINC_FINGER_C2H2_2 [T].
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ID ZN574_XENTR Reviewed; 857 AA.
AC Q6GL52;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 10-MAY-2017, entry version 98.
DE RecName: Full=Zinc finger protein 574;
GN Name=znf574;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; BC074658; AAH74658.1; -; mRNA.
DR RefSeq; NP_001004843.1; NM_001004843.1.
DR RefSeq; XP_012821811.1; XM_012966357.2.
DR UniGene; Str.40645; -.
DR ProteinModelPortal; Q6GL52; -.
DR SMR; Q6GL52; -.
DR STRING; 8364.ENSXETP00000057402; -.
DR PaxDb; Q6GL52; -.
DR Ensembl; ENSXETT00000057402; ENSXETP00000057402; ENSXETG00000027536.
DR GeneID; 448126; -.
DR KEGG; xtr:448126; -.
DR CTD; 64763; -.
DR Xenbase; XB-GENE-1004140; znf574.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00670000098063; -.
DR HOGENOM; HOG000065747; -.
DR HOVERGEN; HBG103121; -.
DR InParanoid; Q6GL52; -.
DR OMA; EDCAMEL; -.
DR OrthoDB; EOG091G02KC; -.
DR TreeFam; TF350791; -.
DR Proteomes; UP000008143; Unassembled WGS sequence.
DR Bgee; ENSXETG00000027536; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; -; 2.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SMART; SM00355; ZnF_C2H2; 20.
DR SUPFAM; SSF57667; SSF57667; 10.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 18.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 19.
PE 2: Evidence at transcript level;
KW Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1 857 Zinc finger protein 574.
FT /FTId=PRO_0000274866.
FT ZN_FING 15 37 C2H2-type 1. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 58 80 C2H2-type 2. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 99 121 C2H2-type 3. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 206 228 C2H2-type 4. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 297 319 C2H2-type 5. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 324 346 C2H2-type 6. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 352 374 C2H2-type 7. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 380 401 C2H2-type 8. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 428 451 C2H2-type 9. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 457 479 C2H2-type 10. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 485 507 C2H2-type 11. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 513 535 C2H2-type 12. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 541 563 C2H2-type 13. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 569 591 C2H2-type 14. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 597 619 C2H2-type 15; degenerate.
FT {ECO:0000255|PROSITE-ProRule:PRU00042}.
FT ZN_FING 628 651 C2H2-type 16. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 681 703 C2H2-type 17. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 709 731 C2H2-type 18. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 737 759 C2H2-type 19. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 765 787 C2H2-type 20. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT COMPBIAS 675 678 Poly-Gly.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 487 507 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 765 787 ismart:ZnF_C2H2 [T]
FT MYHIT 430 451 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 569 596 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 457 484 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 352 374 ismart:ZnF_C2H2 [T]
FT MYHIT 571 591 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 457 479 ismart:ZnF_C2H2 [T]
FT MYHIT 299 319 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 683 703 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 428 451 ismart:ZnF_C2H2 [T]
FT MYHIT 485 507 ismart:ZnF_C2H2 [T]
FT MYHIT 628 651 ismart:ZnF_C2H2 [T]
FT MYHIT 541 563 ismart:ZnF_C2H2 [T]
FT MYHIT 15 37 ismart:ZnF_C2H2 [T]
FT MYHIT 380 401 ismart:ZnF_C2H2 [T]
FT MYHIT 569 591 ismart:ZnF_C2H2 [T]
FT MYHIT 767 787 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 58 80 ismart:ZnF_C2H2 [T]
FT MYHIT 324 346 ismart:ZnF_C2H2 [T]
FT MYHIT 630 651 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 709 736 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 459 479 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 513 535 ismart:ZnF_C2H2 [T]
FT MYHIT 628 656 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 208 228 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 60 80 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 739 759 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 485 512 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 326 346 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 543 563 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 17 37 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 206 228 ismart:ZnF_C2H2 [T]
FT MYHIT 681 703 ismart:ZnF_C2H2 [T]
FT MYHIT 597 617 ismart:ZnF_C2H2 [T]
FT MYHIT 515 535 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 324 351 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 99 126 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 428 456 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 765 792 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 541 568 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 99 121 ismart:ZnF_C2H2 [T]
FT MYHIT 352 374 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 513 535 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 354 374 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 737 764 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 101 121 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 58 85 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 681 708 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 206 233 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 15 42 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 380 406 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 737 759 ismart:ZnF_C2H2 [T]
FT MYHIT 297 319 ismart:ZnF_C2H2 [T]
FT MYHIT 709 731 ismart:ZnF_C2H2 [T]
FT MYHIT 711 731 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 297 319 iprf:ZINC_FINGER_C2H2_2 [T]
SQ SEQUENCE 857 AA; 97090 MW; B9F27F36B7DC3618 CRC64;
MTDSEETVLY VEHRYVCSEC GEEYPSLEEA LEHQQSHAAA LQEPQYQIVG VNSLENQYQC
LECGLLLRTP EDLLAHQELH PTQNEIQKPK RPTRSEIHYE CPECKALFNS QDVWMAHRYT
HMQVQDVSHS KIVLQTDDHV IEDGLQLMCA PAVPSEVHLV TGDPHFHVST PSSASVSHTQ
VLVDLEHSYK KNEGAGEDCA MELLLYKCSE CTQLFQTPGE FLEHQGTHFS GQERISDTNS
HLDQTPQLSL NGQEKEPIIN QGNTCTDYQA ENKELLVQPE GEQAEQDSWT VDREPVFSCG
DCSETFQTTK DLEEHQISHQ NGPFSCPLCS KVFPTYPEVG EHLKSHRSES RYLCVDCGLA
FVSEAVLLNH RRSHLANPLF TCECGLTFLN MTRFLYHRRV HSSKQPDTGA VEEKKTVNSI
APSPAGNFHC DPCGKDFPLL SQFLRHQRFV HALERRHKCP TCGKHFKKGS HLRTHMLTHT
GERPYSCTVC SKSFNSQANL LRHRLTHTGE KPYKCQLCGK AFSQSSTLQQ HQYVHGQAYL
YKCNECGINF HRPYRLLLHQ YHHTGEYPYK CQDCGLSFLL KRLLEVHQLG HRGEEPHRCR
ECGTNFPSVQ RLQDHRCSKA GDGGGEKLEC PICGKKVTSD AHLNTHVAAQ HSGNKRSNVS
SGKGTPVLPR NKLKGGGGKN LECSDCHKTF STETSLQVHR RIHTGERPYP CPDCGKAFRQ
STHLKDHRRL HTGEKPFKCD VCGKAFTIAV RLSEHKRIHT GERPHSCPDC GRAYRSFSNL
WKHRKLHREQ QVQLQEPESQ PADLSSTVAI LETVETIPII ETVEIFPEGS TISVQDIQFE
TLQVENIHLG NIQIGTL
//
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