MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Zinc finger protein 502; |
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| MyHits synonyms | ZN502_HUMAN , Q8TBZ5 , 63437B670A6B22D0 |
 Legends: 1, VARIANT L -> P (in dbSNP:rs6798400); 2, VARIANT Q -> R (in dbSNP:rs56084453); 3, VARIANT E -> A (in dbSNP:rs7640654); 4, ZN_FING C2H2-type 1. {ECO:0000255|PROSITE- ProRule:PRU00042}; 5, ZN_FING C2H2-type 2. {ECO:0000255|PROSITE- ProRule:PRU00042}; 6, ZN_FING C2H2-type 3. {ECO:0000255|PROSITE- ProRule:PRU00042}; 7, ZN_FING C2H2-type 4. {ECO:0000255|PROSITE- ProRule:PRU00042}; 8, ZN_FING C2H2-type 5. {ECO:0000255|PROSITE- ProRule:PRU00042}; 9, ZN_FING C2H2-type 6. {ECO:0000255|PROSITE- ProRule:PRU00042}; 10, ZN_FING C2H2-type 7. {ECO:0000255|PROSITE- ProRule:PRU00042}; 11, ZN_FING C2H2-type 8. {ECO:0000255|PROSITE- ProRule:PRU00042}; 12, ZN_FING C2H2-type 9. {ECO:0000255|PROSITE- ProRule:PRU00042}; 13, ZN_FING C2H2-type 10. {ECO:0000255|PROSITE- ProRule:PRU00042}; 14, ZN_FING C2H2-type 11. {ECO:0000255|PROSITE- ProRule:PRU00042}; 15, ZN_FING C2H2-type 12. {ECO:0000255|PROSITE- ProRule:PRU00042}; 16, ZN_FING C2H2-type 13. {ECO:0000255|PROSITE- ProRule:PRU00042}; 17, ZN_FING C2H2-type 14. {ECO:0000255|PROSITE- ProRule:PRU00042}; 18, ipat:ZINC_FINGER_C2H2_1 [T]; 19, ismart:ZnF_C2H2 [T]; 20, iprf:ZINC_FINGER_C2H2_2 [T].
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ID ZN502_HUMAN Reviewed; 544 AA.
AC Q8TBZ5;
DT 15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 10-MAY-2017, entry version 129.
DE RecName: Full=Zinc finger protein 502;
GN Name=ZNF502;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- INTERACTION:
CC P03419:M (xeno); NbExp=3; IntAct=EBI-10273699, EBI-10042882;
CC Q13077:TRAF1; NbExp=5; IntAct=EBI-10273699, EBI-359224;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
CC -----------------------------------------------------------------------
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DR EMBL; BC028377; AAH28377.1; -; mRNA.
DR CCDS; CCDS2719.1; -.
DR RefSeq; NP_001127912.1; NM_001134440.1.
DR RefSeq; NP_001127913.1; NM_001134441.1.
DR RefSeq; NP_001127914.1; NM_001134442.1.
DR RefSeq; NP_001269809.1; NM_001282880.1.
DR RefSeq; NP_149987.2; NM_033210.4.
DR RefSeq; XP_016862929.1; XM_017007440.1.
DR UniGene; Hs.224843; -.
DR ProteinModelPortal; Q8TBZ5; -.
DR SMR; Q8TBZ5; -.
DR BioGrid; 124825; 2.
DR IntAct; Q8TBZ5; 2.
DR STRING; 9606.ENSP00000296091; -.
DR iPTMnet; Q8TBZ5; -.
DR PhosphoSitePlus; Q8TBZ5; -.
DR BioMuta; ZNF502; -.
DR DMDM; 45477319; -.
DR MaxQB; Q8TBZ5; -.
DR PaxDb; Q8TBZ5; -.
DR PeptideAtlas; Q8TBZ5; -.
DR PRIDE; Q8TBZ5; -.
DR DNASU; 91392; -.
DR Ensembl; ENST00000296091; ENSP00000296091; ENSG00000196653.
DR Ensembl; ENST00000436624; ENSP00000406469; ENSG00000196653.
DR Ensembl; ENST00000449836; ENSP00000397390; ENSG00000196653.
DR Ensembl; ENST00000626630; ENSP00000487139; ENSG00000281448.
DR Ensembl; ENST00000628995; ENSP00000485847; ENSG00000281448.
DR Ensembl; ENST00000630464; ENSP00000486576; ENSG00000281448.
DR GeneID; 91392; -.
DR KEGG; hsa:91392; -.
DR UCSC; uc003cns.4; human.
DR CTD; 91392; -.
DR DisGeNET; 91392; -.
DR GeneCards; ZNF502; -.
DR HGNC; HGNC:23718; ZNF502.
DR HPA; HPA024761; -.
DR HPA; HPA029557; -.
DR neXtProt; NX_Q8TBZ5; -.
DR OpenTargets; ENSG00000196653; -.
DR PharmGKB; PA134866656; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00870000136370; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR InParanoid; Q8TBZ5; -.
DR OMA; EYQDSTF; -.
DR OrthoDB; EOG091G02KC; -.
DR PhylomeDB; Q8TBZ5; -.
DR TreeFam; TF341817; -.
DR GenomeRNAi; 91392; -.
DR PRO; PR:Q8TBZ5; -.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000196653; -.
DR CleanEx; HS_ZNF502; -.
DR ExpressionAtlas; Q8TBZ5; baseline and differential.
DR Genevisible; Q8TBZ5; HS.
DR GO; GO:0005634; C:nucleus; IDA:AgBase.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0044794; P:positive regulation by host of viral process; IMP:AgBase.
DR GO; GO:0044791; P:positive regulation by host of viral release from host cell; IMP:AgBase.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR InterPro; IPR013087; Znf_C2H2_type.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; SSF57667; 8.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE 1: Evidence at protein level;
KW Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1 544 Zinc finger protein 502.
FT /FTId=PRO_0000047623.
FT ZN_FING 155 177 C2H2-type 1. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 183 205 C2H2-type 2. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 211 233 C2H2-type 3. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 239 261 C2H2-type 4. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 267 289 C2H2-type 5. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 295 317 C2H2-type 6. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 323 345 C2H2-type 7. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 351 373 C2H2-type 8. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 379 401 C2H2-type 9. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 407 429 C2H2-type 10. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 435 457 C2H2-type 11. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 463 485 C2H2-type 12. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 491 513 C2H2-type 13. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT ZN_FING 519 541 C2H2-type 14. {ECO:0000255|PROSITE-
FT ProRule:PRU00042}.
FT VARIANT 28 28 L -> P (in dbSNP:rs6798400).
FT /FTId=VAR_033574.
FT VARIANT 174 174 Q -> R (in dbSNP:rs56084453).
FT /FTId=VAR_061953.
FT VARIANT 243 243 E -> A (in dbSNP:rs7640654).
FT /FTId=VAR_024220.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 409 429 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 269 289 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 435 457 ismart:ZnF_C2H2 [T]
FT MYHIT 155 177 ismart:ZnF_C2H2 [T]
FT MYHIT 519 544 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 379 406 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 239 261 ismart:ZnF_C2H2 [T]
FT MYHIT 379 401 ismart:ZnF_C2H2 [T]
FT MYHIT 435 462 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 407 429 ismart:ZnF_C2H2 [T]
FT MYHIT 157 177 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 267 289 ismart:ZnF_C2H2 [T]
FT MYHIT 183 205 ismart:ZnF_C2H2 [T]
FT MYHIT 211 238 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 437 457 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 463 490 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 325 345 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 241 261 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 295 317 ismart:ZnF_C2H2 [T]
FT MYHIT 267 294 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 155 182 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 407 434 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 491 513 ismart:ZnF_C2H2 [T]
FT MYHIT 491 518 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 463 485 ismart:ZnF_C2H2 [T]
FT MYHIT 519 541 ismart:ZnF_C2H2 [T]
FT MYHIT 185 205 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 323 350 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 351 378 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 381 401 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 239 266 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 295 322 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 465 485 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 493 513 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 353 373 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 297 317 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 521 541 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 323 345 ismart:ZnF_C2H2 [T]
FT MYHIT 183 210 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 211 233 ismart:ZnF_C2H2 [T]
FT MYHIT 351 373 ismart:ZnF_C2H2 [T]
FT MYHIT 213 233 ipat:ZINC_FINGER_C2H2_1 [T]
SQ SEQUENCE 544 AA; 62920 MW; 63437B670A6B22D0 CRC64;
MLNMQGAEER DIRRETCPGW VNKNKPALEQ DVCKIDSSGI VVKRFQEDEY QDSTFEEKYA
CEGMKENSPR EIAESCLFQE GGFGRITFIH KEAPPEIISQ GYNFEKSLLL TSSLVTRLRV
STEESLHQWE TSNIQTNDIS DQSKCPTLCT QKKSWKCNEC GKTFTQSSSL TQHQRTHTGE
RPYTCEECGK AFSRSSFLVQ HQRIHTGVKP YGCEQCGKTF RCRSFLTQHQ RIHTGEKPYK
CNECGNSFRN HSHLTEHQRI HTGEKPYKCN RCGKAFNQNT HLIHHQRIHT GEKPYICSEC
GSSFRKHSNL TQHQRIHTGE KPHKCDECGK TFQTKANLSQ HQRIHSGEKP YKCKECGKAF
CQSPSLIKHQ RIHTGEKPYK CKECGKAFTQ STPLTKHQRI HTGERPYKCS ECGKAFIQSI
CLIRHQRSHT GEKPYKCNEC GKGFNQNTCL TQHMRIHTGE KPYKCKECGK AFAHSSSLTE
HHRTHTGEKL YKCSECEKTF RKYAHLSEHY RIHTGEKPYE CIECGKFFRH SSVLFRHQKL
HSGD
//
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