Entry euk:TM251_MOUSE

ID   TM251_MOUSE             Reviewed;         163 AA.
AC   Q8BH26;
DT   02-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   10-MAY-2017, entry version 91.
DE   RecName: Full=Transmembrane protein 251;
GN   Name=Tmem251;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Eye, and Olfactory bulb;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA   Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA   Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA   Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA   Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA   Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA   di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA   Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA   Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA   Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA   Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA   Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA   Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA   Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA   Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA   Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA   Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA   Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA   Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA   Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA   Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA   Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA   Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA   Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA   Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA   Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA   Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA   Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA   Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA   Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA   Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA   Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Retina;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM251 family. {ECO:0000305}.
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DR   EMBL; AK032513; BAC27904.1; -; mRNA.
DR   EMBL; AK052027; BAC34834.1; -; mRNA.
DR   EMBL; BC096606; AAH96606.1; -; mRNA.
DR   CCDS; CCDS49146.1; -.
DR   RefSeq; NP_001311444.1; NM_001324515.1.
DR   RefSeq; NP_796114.1; NM_177140.3.
DR   UniGene; Mm.86546; -.
DR   PaxDb; Q8BH26; -.
DR   PRIDE; Q8BH26; -.
DR   Ensembl; ENSMUST00000057416; ENSMUSP00000054611; ENSMUSG00000046675.
DR   GeneID; 320351; -.
DR   KEGG; mmu:320351; -.
DR   UCSC; uc007oul.1; mouse.
DR   CTD; 26175; -.
DR   MGI; MGI:2443862; Tmem251.
DR   eggNOG; ENOG410IVYY; Eukaryota.
DR   eggNOG; ENOG4111FFW; LUCA.
DR   GeneTree; ENSGT00390000007473; -.
DR   HOGENOM; HOG000111822; -.
DR   HOVERGEN; HBG058826; -.
DR   InParanoid; Q8BH26; -.
DR   OMA; LPFWFWT; -.
DR   OrthoDB; EOG091G14P1; -.
DR   PhylomeDB; Q8BH26; -.
DR   TreeFam; TF332722; -.
DR   PRO; PR:Q8BH26; -.
DR   Proteomes; UP000000589; Chromosome 12.
DR   Bgee; ENSMUSG00000046675; -.
DR   CleanEx; MM_D230037D09RIK; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028024; TMEM251.
DR   Pfam; PF15190; TMEM251; 1.
DR   ProDom; PD641273; PD641273; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN         1    163       Transmembrane protein 251.
FT                                /FTId=PRO_0000089917.
FT   TRANSMEM     40     60       Helical. {ECO:0000255}.
FT   TRANSMEM     98    118       Helical. {ECO:0000255}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        34    161       ipfam:TMEM251 [T]
SQ   SEQUENCE   163 AA;  18720 MW;  55AF92B104E90506 CRC64;
     MPKAPDCSEL SDSCSLAGGT GRFSGPLHRA WRMMNFRQRM GWIGVGLYLL ASAAAFYYVF
     EINETYNRLA LEHILQHPEE PREGTTWTHS LKARLLSLPF WLWTIIFLIP YLQMFLFLYS
     CTRADPKTVG YCIIPICLAV ICNRHQAFVK ASNQISRLQL IDT
//