MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Transmembrane protein 247; |
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| MyHits synonyms | TM247_HUMAN , A6NEH6 , 83A376D61158E80E |
 Legends: 1, TRANSMEM Helical. {ECO:0000255}; 2, COILED {ECO:0000255}.
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ID TM247_HUMAN Reviewed; 219 AA.
AC A6NEH6;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 2.
DT 15-MAR-2017, entry version 66.
DE RecName: Full=Transmembrane protein 247;
GN Name=TMEM247;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA Waterston R.H., Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2
RT and 4.";
RL Nature 434:724-731(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AC018682; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS56117.1; -.
DR RefSeq; NP_001138523.1; NM_001145051.2.
DR UniGene; Hs.733348; -.
DR ProteinModelPortal; A6NEH6; -.
DR STRING; 9606.ENSP00000388684; -.
DR PhosphoSitePlus; A6NEH6; -.
DR BioMuta; TMEM247; -.
DR PaxDb; A6NEH6; -.
DR PRIDE; A6NEH6; -.
DR Ensembl; ENST00000434431; ENSP00000388684; ENSG00000187600.
DR GeneID; 388946; -.
DR KEGG; hsa:388946; -.
DR UCSC; uc061ivl.1; human.
DR CTD; 388946; -.
DR GeneCards; TMEM247; -.
DR HGNC; HGNC:42967; TMEM247.
DR neXtProt; NX_A6NEH6; -.
DR OpenTargets; ENSG00000187600; -.
DR eggNOG; ENOG410J4VW; Eukaryota.
DR eggNOG; ENOG41113DE; LUCA.
DR GeneTree; ENSGT00390000002879; -.
DR HOGENOM; HOG000168313; -.
DR HOVERGEN; HBG108691; -.
DR InParanoid; A6NEH6; -.
DR OMA; LFSKHYL; -.
DR OrthoDB; EOG091G0P0P; -.
DR PhylomeDB; A6NEH6; -.
DR TreeFam; TF337834; -.
DR GenomeRNAi; 388946; -.
DR PRO; PR:A6NEH6; -.
DR Proteomes; UP000005640; Chromosome 2.
DR Bgee; ENSG00000187600; -.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029200; TMEM247.
DR Pfam; PF15444; TMEM247; 2.
PE 4: Predicted;
KW Coiled coil; Complete proteome; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1 219 Transmembrane protein 247.
FT /FTId=PRO_0000328813.
FT TRANSMEM 167 187 Helical. {ECO:0000255}.
FT TRANSMEM 194 214 Helical. {ECO:0000255}.
FT COILED 121 156 {ECO:0000255}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 1 141 ipfam:TMEM247 [T]
FT MYHIT 140 219 ipfam:TMEM247 [T]
SQ SEQUENCE 219 AA; 25168 MW; 83A376D61158E80E CRC64;
MAAEDREMME ARGAGESCPT FPKMVPGDSK SEGKPRAYLE AESQKPDSSY DYLEEMEACE
DGGCQGPLKS LSPKSCRATK GQAGDGPKPA ELPPTPGTER NPEMELEKVR MEFELTRLKY
LHEKNQRQRQ HEVVMEQLQR ERQHEVVMEQ LQQEAAPRLF SGGLQNFLLP QNQFAMFLYC
FIFIHIIYVT KEMVFFLFAK HYLFCIAAIL LCLIKTFWS
//
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