ID TM247_BOVIN Reviewed; 217 AA.
AC Q2YDG1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 2.
DT 15-MAR-2017, entry version 56.
DE RecName: Full=Transmembrane protein 247;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC Pecora; Bovidae; Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford;
RX PubMed=19390049; DOI=10.1126/science.1169588;
RG The bovine genome sequencing and analysis consortium;
RT "The genome sequence of taurine cattle: a window to ruminant biology
RT and evolution.";
RL Science 324:522-528(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI10241.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
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DR EMBL; AAFC03016455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC110240; AAI10241.1; ALT_INIT; mRNA.
DR RefSeq; NP_001070537.2; NM_001077069.1.
DR UniGene; Bt.50730; -.
DR PaxDb; Q2YDG1; -.
DR PRIDE; Q2YDG1; -.
DR Ensembl; ENSBTAT00000005367; ENSBTAP00000005367; ENSBTAG00000004105.
DR GeneID; 768009; -.
DR KEGG; bta:768009; -.
DR CTD; 388946; -.
DR eggNOG; ENOG410J4VW; Eukaryota.
DR eggNOG; ENOG41113DE; LUCA.
DR GeneTree; ENSGT00390000002879; -.
DR HOGENOM; HOG000168313; -.
DR HOVERGEN; HBG108691; -.
DR InParanoid; Q2YDG1; -.
DR OMA; LFSKHYL; -.
DR OrthoDB; EOG091G0P0P; -.
DR TreeFam; TF337834; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000004105; -.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029200; TMEM247.
DR Pfam; PF15444; TMEM247; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Complete proteome; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1 217 Transmembrane protein 247.
FT /FTId=PRO_0000328812.
FT TRANSMEM 165 185 Helical. {ECO:0000255}.
FT TRANSMEM 192 212 Helical. {ECO:0000255}.
FT COILED 109 154 {ECO:0000255}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 1 217 ipfam:TMEM247 [T]
SQ SEQUENCE 217 AA; 24443 MW; CD8B05FAFE393950 CRC64;
MATEDREMME GRGAGESCPT FPKMAPDDPM SEGKPRASLP QEADTPKPDS SYDYLEEMET
CEDGGCPGPP KVLSSKAGPA TTKGQAGDGL ELAELPSVPA TAAPGSPVRE RDAEMELEKV
RMEFELKRLK YLHEENERQR QHEEVMEQLQ QQATPRLFSG GLQDLLLPQN QFAMFLYCFI
FIHIIYVTKE MIFFLFSKHY LFCIAAILLC LIKTLWS
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