ID TM174_RAT Reviewed; 243 AA.
AC Q68FU0;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 10-MAY-2017, entry version 66.
DE RecName: Full=Transmembrane protein 174;
GN Name=Tmem174;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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DR EMBL; BC079357; AAH79357.1; -; mRNA.
DR RefSeq; NP_001019469.1; NM_001024298.1.
DR UniGene; Rn.122955; -.
DR PaxDb; Q68FU0; -.
DR Ensembl; ENSRNOT00000020879; ENSRNOP00000020879; ENSRNOG00000015472.
DR GeneID; 499516; -.
DR KEGG; rno:499516; -.
DR UCSC; RGD:1561129; rat.
DR CTD; 134288; -.
DR RGD; 1561129; Tmem174.
DR eggNOG; ENOG410IR9J; Eukaryota.
DR eggNOG; ENOG410YMC9; LUCA.
DR GeneTree; ENSGT00390000004161; -.
DR HOGENOM; HOG000059655; -.
DR HOVERGEN; HBG095684; -.
DR InParanoid; Q68FU0; -.
DR OMA; PPQYYTI; -.
DR OrthoDB; EOG091G0I7E; -.
DR PhylomeDB; Q68FU0; -.
DR TreeFam; TF335512; -.
DR PRO; PR:Q68FU0; -.
DR Proteomes; UP000002494; Chromosome 2.
DR Bgee; ENSRNOG00000015472; -.
DR Genevisible; Q68FU0; RN.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR027835; TMEM174.
DR PANTHER; PTHR31020; PTHR31020; 1.
DR Pfam; PF15029; TMEM174; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Endoplasmic reticulum; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1 243 Transmembrane protein 174.
FT /FTId=PRO_0000282580.
FT TRANSMEM 40 60 Helical. {ECO:0000255}.
FT TRANSMEM 73 93 Helical. {ECO:0000255}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 9 240 ipfam:TMEM174 [T]
SQ SEQUENCE 243 AA; 26478 MW; 7892FF53CE7EDD57 CRC64;
MEQSSNRPED FPLNVFSVTP YTPSTADIQV SDDDKAGATL LFSGIFLGLV GITFTVMGWI
KYQGVSHFEW TQLLGPILLS VGVTFILISV CKFKMLSCQL CTDNEERVLD SDQTSGGQSF
VFTGINQPIT FHGATVVQYI PPPYGSQEPL GMNTTYLQPM MNPCGLVPSS GAVAATPSPP
QYYTIYPQDN AAFVESEGFS PFVGAGHDRP SSDADQLEGT QMGEEERVCF SPPPYEEIYA
LPR
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