Legends: 1, Phosphoserine. {ECO:0000250|UniProtKB:Q8R0J4}; 2, CONFLICT E -> V (in Ref. 1; CR849934). {ECO:0000305}; 3, TRANSMEM Helical. {ECO:0000255}; 4, TOPO_DOM Extracellular. {ECO:0000255}; 5, TOPO_DOM Cytoplasmic. {ECO:0000255}; 6, VAR_SEQ Missing (in isoform 2). {ECO:0000303|Ref.2}.
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ID TM134_BOVIN Reviewed; 195 AA.
AC Q05B54;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 2.
DT 15-MAR-2017, entry version 70.
DE RecName: Full=Transmembrane protein 134;
GN Name=TMEM134;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC Pecora; Bovidae; Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC TISSUE=Endometrium;
RA Renard J.P., Lewin H.A., Yang J., Hernandez A., Sandra O.,
RA Everts R.E., Hue I.;
RT "Endometrium ESTs (bcbp).";
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q05B54-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q05B54-2; Sequence=VSP_023451;
CC -!- SIMILARITY: Belongs to the TMEM134/TMEM230 family. {ECO:0000305}.
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DR EMBL; CR849934; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BC122796; AAI22797.1; -; mRNA.
DR RefSeq; NP_001073723.1; NM_001080254.2. [Q05B54-2]
DR RefSeq; XP_005227098.1; XM_005227041.2. [Q05B54-1]
DR UniGene; Bt.111432; -.
DR STRING; 9913.ENSBTAP00000029961; -.
DR PaxDb; Q05B54; -.
DR PRIDE; Q05B54; -.
DR Ensembl; ENSBTAT00000006284; ENSBTAP00000006284; ENSBTAG00000004786. [Q05B54-2]
DR Ensembl; ENSBTAT00000029973; ENSBTAP00000029961; ENSBTAG00000004786. [Q05B54-1]
DR GeneID; 510129; -.
DR KEGG; bta:510129; -.
DR CTD; 80194; -.
DR eggNOG; KOG4753; Eukaryota.
DR eggNOG; ENOG4111TWA; LUCA.
DR GeneTree; ENSGT00390000011766; -.
DR HOGENOM; HOG000145514; -.
DR HOVERGEN; HBG093689; -.
DR InParanoid; Q05B54; -.
DR OMA; RSYHACC; -.
DR OrthoDB; EOG091G0P6K; -.
DR TreeFam; TF323560; -.
DR Proteomes; UP000009136; Chromosome 29.
DR Bgee; ENSBTAG00000004786; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR008590; DUF872_TM.
DR Pfam; PF05915; DUF872; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Complete proteome; Membrane; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1 195 Transmembrane protein 134.
FT /FTId=PRO_0000279484.
FT TOPO_DOM 1 122 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 123 143 Helical. {ECO:0000255}.
FT TOPO_DOM 144 154 Extracellular. {ECO:0000255}.
FT TRANSMEM 155 175 Helical. {ECO:0000255}.
FT TOPO_DOM 176 195 Cytoplasmic. {ECO:0000255}.
FT MOD_RES 93 93 Phosphoserine.
FT {ECO:0000250|UniProtKB:Q8R0J4}.
FT VAR_SEQ 136 150 Missing (in isoform 2).
FT {ECO:0000303|Ref.2}.
FT /FTId=VSP_023451.
FT CONFLICT 194 194 E -> V (in Ref. 1; CR849934).
FT {ECO:0000305}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 57 193 ipfam:DUF872 [T]
SQ SEQUENCE 195 AA; 21567 MW; 887C1872E8A40D31 CRC64;
MSASRPQFSI DDAFELSLED TGPGLEPSGV ARFGPLHFER RARFEVADED KQSRLRYQNL
ENDEDGAQAS PEPDGGVSSR DSGQTSIRSS QWSFSSISSS TQRSYNACCS WTQHPLIQKN
HRVVLASFLL LLLGLVLILT GVGLEVAPSP GVSSAIFFVP GFLLLVPGVY HVIFIYCAVK
GHRGFQFFYL PYFEK
//
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