ID Q8VF43_MOUSE Unreviewed; 315 AA.
AC Q8VF43;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 10-MAY-2017, entry version 121.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN Name=Olfr1325 {ECO:0000313|Ensembl:ENSMUSP00000052441,
GN ECO:0000313|MGI:MGI:3031159};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000313|EMBL:AAL61360.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [2] {ECO:0000313|EMBL:AAL61360.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [3] {ECO:0000313|EMBL:AAL61360.1}
RP NUCLEOTIDE SEQUENCE.
RA Adams M.;
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000052441, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000052441,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [5] {ECO:0000313|Ensembl:ENSMUSP00000052441}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000052441};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00521146};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC ECO:0000256|SAAS:SAAS00521146}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00591716}.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AL669976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY073697; AAL61360.1; -; Genomic_DNA.
DR RefSeq; NP_666510.1; NM_146398.1.
DR UniGene; Mm.377477; -.
DR STRING; 10090.ENSMUSP00000052441; -.
DR Ensembl; ENSMUST00000054541; ENSMUSP00000052441; ENSMUSG00000051706.
DR GeneID; 258393; -.
DR KEGG; mmu:258393; -.
DR UCSC; uc009tph.1; mouse.
DR CTD; 258393; -.
DR MGI; MGI:3031159; Olfr1325.
DR eggNOG; ENOG410IJ1V; Eukaryota.
DR eggNOG; ENOG41118P8; LUCA.
DR GeneTree; ENSGT00760000119058; -.
DR HOGENOM; HOG000041364; -.
DR HOVERGEN; HBG017625; -.
DR KO; K04257; -.
DR OrthoDB; EOG091G0AZH; -.
DR TreeFam; TF352686; -.
DR Proteomes; UP000000589; Chromosome X.
DR Bgee; ENSMUSG00000051706; -.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00521172};
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW ECO:0000256|SAAS:SAAS00529918};
KW Membrane {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00520911, ECO:0000256|SAAS:SAAS00521172};
KW Olfaction {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00521184};
KW Receptor {ECO:0000256|RuleBase:RU000688,
KW ECO:0000256|SAAS:SAAS00529918};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00521184};
KW Transducer {ECO:0000256|RuleBase:RU000688,
KW ECO:0000256|SAAS:SAAS00529918};
KW Transmembrane {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00520911};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW ECO:0000256|SAAS:SAAS00520911}.
FT TRANSMEM 32 54 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 66 87 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 107 126 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 146 173 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 202 230 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 242 265 Helical. {ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 277 297 Helical. {ECO:0000256|RuleBase:RU363047}.
FT DOMAIN 47 295 G_PROTEIN_RECEP_F1_2.
FT {ECO:0000259|PROSITE:PS50262}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 47 295 iprf:G_PROTEIN_RECEP_F1_2 [T]
FT MYHIT 116 132 ipat:G_PROTEIN_RECEP_F1_1 [T]
SQ SEQUENCE 315 AA; 35473 MW; 75E40C581CC87B9B CRC64;
MKKMNYQEIG NYTKVTEFIL VGLSRHPTSQ SVVFWTLMFL YIVTLAGNSL IIFLVGGNSQ
LHTPMYFFLG NLSLLDLLFS TSVVPLIMVN SLYNFSTISY SSCFTQLAFR AFLALAECFL
LAIMAYDRFV AISNPLRYNL VMSSRVCIFM ALLAWMAALL LTVLPILIFP ISFCGQNVVN
HFSCEVQAIF KLLCSNTISL QIMMIACAVI SMPVPLMFIL FSYLCILKAV LRIHPTKARL
KAFSTCASHL IVVTIYFGTL IYIYMRPQSK ISHNGDKIVS IFYAAVTPML NPLIYTLRNK
DVKAVLRRVN CGVKS
//
|
