ID Q8VCI1_MOUSE Unreviewed; 386 AA.
AC Q8VCI1;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 10-MAY-2017, entry version 131.
DE SubName: Full=Zinc finger protein 566 {ECO:0000313|EMBL:AAH19790.1, ECO:0000313|Ensembl:ENSMUSP00000086164};
GN Name=Zfp566 {ECO:0000313|EMBL:AAH19790.1,
GN ECO:0000313|Ensembl:ENSMUSP00000086164, ECO:0000313|MGI:MGI:1919806};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH19790.1};
RN [1] {ECO:0000313|EMBL:AAH19790.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Mix FVB/N {ECO:0000313|EMBL:AAH19790.1};
RC TISSUE=Mammary tumor. WAP-TGF alpha model. 7 months old
RC {ECO:0000313|EMBL:AAH19790.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000086164, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000086164,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000086164}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000086164};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR EMBL; AC157948; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC164703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC019790; AAH19790.1; -; mRNA.
DR RefSeq; NP_690027.1; NM_152814.2.
DR UniGene; Mm.441512; -.
DR STRING; 10090.ENSMUSP00000086164; -.
DR Ensembl; ENSMUST00000088785; ENSMUSP00000086164; ENSMUSG00000078768.
DR GeneID; 72556; -.
DR KEGG; mmu:72556; -.
DR UCSC; uc009gdd.1; mouse.
DR CTD; 72556; -.
DR MGI; MGI:1919806; Zfp566.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00840000129704; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR KO; K09228; -.
DR OMA; TRGQWPV; -.
DR OrthoDB; EOG091G02KC; -.
DR TreeFam; TF338743; -.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000078768; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 5.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW Metal-binding {ECO:0000256|SAAS:SAAS00780264};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|SAAS:SAAS00780289};
KW Zinc {ECO:0000256|SAAS:SAAS00780264};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00780264}.
FT DOMAIN 6 104 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT DOMAIN 167 194 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 195 222 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 223 250 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 251 278 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 279 306 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 307 334 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 335 362 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 223 250 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 225 245 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 167 194 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 281 301 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 253 273 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 335 362 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 6 104 iprf:KRAB [T]
FT MYHIT 251 278 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 307 329 ismart:ZnF_C2H2 [T]
FT MYHIT 335 357 ismart:ZnF_C2H2 [T]
FT MYHIT 197 217 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 195 217 ismart:ZnF_C2H2 [T]
FT MYHIT 337 357 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 309 329 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 251 273 ismart:ZnF_C2H2 [T]
FT MYHIT 167 189 ismart:ZnF_C2H2 [T]
FT MYHIT 195 222 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 5 45 ipfam:KRAB [T]
FT MYHIT 169 189 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 279 306 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 6 67 ismart:KRAB [T]
FT MYHIT 307 334 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 279 301 ismart:ZnF_C2H2 [T]
FT MYHIT 223 245 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 386 AA; 45293 MW; 42909D6B3B1FE082 CRC64;
MAQVSVLFHD VYIDFSQEEW ECLTEEQRDL YRDVMLENYS NLLSMVLESR CEAQKLFLKK
ELYEIETAQW EIMRKLTRQD LQCSSLSSAR EWHGHRERQR GSQERQFSEL IINRDDVPTL
SQCPSFRLQQ IIKNKEKYCA SKENREHYKH GSRFATHQIV RTTEKPYECK DCGKTFRHPS
GLTHHHKIHT GKKPFECKEC GKTFICGSDL TRHHRIHTGE KPYECKDCGK AFSSGSNFTR
HQRIHTGEKP YECKECGKAF SSGSNFTQHQ RIHTGEKPYE CKECGNAFSQ SSQLIKHQRI
HTGEKPYECK ECEKAFRSGS DLTRHQRIHT GEKPYECKIC GKAYSQSSQL ISHHRIHGGK
KAYEDEDGGK NFIYNSQPIQ HQNLYW
//
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