ID Q8K3N2_MOUSE Unreviewed; 308 AA.
AC Q8K3N2;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 10-MAY-2017, entry version 101.
DE SubName: Full=MCG142328 {ECO:0000313|EMBL:EDL32604.1};
DE SubName: Full=Vomeronasal 1 receptor 188 {ECO:0000313|Ensembl:ENSMUSP00000089333};
DE SubName: Full=Vomeronasal receptor V1RH17 {ECO:0000313|EMBL:AAK98777.1};
GN Name=Vmn1r188 {ECO:0000313|Ensembl:ENSMUSP00000089333,
GN ECO:0000313|MGI:MGI:2182259};
GN Synonyms=V1rh17 {ECO:0000313|MGI:MGI:2182259};
GN ORFNames=mCG_142328 {ECO:0000313|EMBL:EDL32604.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000313|EMBL:AAK98777.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6 {ECO:0000313|EMBL:AAK98777.1};
RX PubMed=11802169; DOI=10.1038/nn795;
RA Rodriguez I., Del Punta K., Rothman A., Ishii T., Mombaerts P.;
RT "Multiple new and isolated families within the mouse superfamily of
RT V1r vomeronasal receptors.";
RL Nat. Neurosci. 5:134-140(2002).
RN [2] {ECO:0000313|EMBL:EDL32604.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mixed {ECO:0000313|EMBL:EDL32604.1};
RX PubMed=12040188; DOI=10.1126/science.1069193;
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R.,
RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A.,
RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.,
RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K.,
RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J.,
RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R.,
RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H.,
RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A.,
RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A.,
RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C.,
RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C.,
RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B.,
RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E.,
RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R.,
RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C.,
RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L.,
RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S.,
RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L.,
RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R.,
RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R.,
RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J.,
RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L.,
RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C.,
RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A.,
RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H.,
RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L.,
RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M.,
RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K.,
RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S.,
RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J.,
RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G.,
RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.;
RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and
RT the human genome.";
RL Science 296:1661-1671(2002).
RN [3] {ECO:0000313|EMBL:EDL32604.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mixed {ECO:0000313|EMBL:EDL32604.1};
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000089333, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000089333,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [5] {ECO:0000313|Ensembl:ENSMUSP00000089333}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000089333};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR EMBL; AL590614; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY044667; AAK98777.1; -; Genomic_DNA.
DR EMBL; CH466561; EDL32604.1; -; Genomic_DNA.
DR RefSeq; NP_665849.1; NM_145850.1.
DR UniGene; Mm.377269; -.
DR Ensembl; ENSMUST00000091739; ENSMUSP00000089333; ENSMUSG00000069299.
DR GeneID; 252912; -.
DR KEGG; mmu:252912; -.
DR UCSC; uc007psf.1; mouse.
DR CTD; 252912; -.
DR MGI; MGI:2182259; Vmn1r188.
DR eggNOG; ENOG410IKIB; Eukaryota.
DR eggNOG; ENOG4111F74; LUCA.
DR GeneTree; ENSGT00840000129802; -.
DR HOGENOM; HOG000231675; -.
DR HOVERGEN; HBG107138; -.
DR KO; K04614; -.
DR OMA; CYIMLES; -.
DR OrthoDB; EOG09070AZD; -.
DR Proteomes; UP000000589; Chromosome 13.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:MGI.
DR GO; GO:0005550; F:pheromone binding; ISS:MGI.
DR GO; GO:0016503; F:pheromone receptor activity; ISS:MGI.
DR GO; GO:0019236; P:response to pheromone; ISS:MGI.
DR GO; GO:0007606; P:sensory perception of chemical stimulus; IBA:GO_Central.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR004072; Vmron_rcpt_1.
DR Pfam; PF03402; V1R; 1.
DR PRINTS; PR01534; VOMERONASL1R.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:AAK98777.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12 31 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43 62 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 92 112 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 124 145 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 177 205 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 226 246 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 266 285 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 21 284 G_PROTEIN_RECEP_F1_2.
FT {ECO:0000259|PROSITE:PS50262}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 33 295 ipfam:V1R [T]
FT MYHIT 21 284 iprf:G_PROTEIN_RECEP_F1_2 [T]
SQ SEQUENCE 308 AA; 35481 MW; 1F82179B2C9D8D79 CRC64;
MVLQFIKETF FFFMTMIGTL GNISVSVDYF FHLLEGVKKK PIHLILIHLA FTNILILLTK
GFRKTVAAFG LRNFLDDIGC KIIVYLERVA RGLSICTSSL LTVVQAIIIS PTGSGWRRLR
PKSAWHILPF FSFFWILNAL ISMNLTHSIR STGLNISQLR NGDNYCYIML ESQEIKWIFL
ILMVLRDAVF QGAMGGASGY MVFLLHKHHQ QVLYLQNSKF LYKTPPELRA AQSVLLLMLC
FVFFYWTDCA FSFFLSLSLE EYSLMVNIHE FLTLGYAIFS PFVLIHRDGL LAEQWETLKQ
CVSHLSDQ
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