ID Q7ZU70_DANRE Unreviewed; 479 AA.
AC Q7ZU70;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 10-MAY-2017, entry version 123.
DE SubName: Full=Tripartite motif-containing 47 {ECO:0000313|Ensembl:ENSDARP00000073663};
DE SubName: Full=Zgc:56368 {ECO:0000313|EMBL:AAH49412.1};
GN Name=trim47 {ECO:0000313|Ensembl:ENSDARP00000073663,
GN ECO:0000313|ZFIN:ZDB-GENE-040426-1000};
GN Synonyms=zgc:56368 {ECO:0000313|EMBL:AAH49412.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH49412.1};
RN [1] {ECO:0000313|EMBL:AAH49412.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:AAH49412.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000073663}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000073663};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000073663, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000073663,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
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DR EMBL; BX511060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC049412; AAH49412.1; -; mRNA.
DR RefSeq; NP_956578.1; NM_200284.1.
DR UniGene; Dr.105276; -.
DR Ensembl; ENSDART00000079207; ENSDARP00000073663; ENSDARG00000056678.
DR GeneID; 393254; -.
DR KEGG; dre:393254; -.
DR CTD; 91107; -.
DR ZFIN; ZDB-GENE-040426-1000; trim47.
DR eggNOG; KOG2177; Eukaryota.
DR eggNOG; ENOG4111G04; LUCA.
DR GeneTree; ENSGT00760000118838; -.
DR HOGENOM; HOG000146434; -.
DR OMA; SANFETI; -.
DR OrthoDB; EOG091G06ZT; -.
DR TreeFam; TF342569; -.
DR Reactome; R-DRE-445355; Smooth Muscle Contraction.
DR Proteomes; UP000000437; Chromosome 10.
DR Bgee; ENSDARG00000056678; -.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00162; RING; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR003879; Butyrophylin.
DR InterPro; IPR013320; ConA-like_dom.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Metal-binding {ECO:0000256|SAAS:SAAS00596386};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Zinc {ECO:0000256|SAAS:SAAS00596386};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00596386}.
FT DOMAIN 17 61 RING-type. {ECO:0000259|PROSITE:PS50089}.
FT DOMAIN 101 142 B box-type.
FT {ECO:0000259|PROSITE:PS50119}.
FT DOMAIN 288 479 B30.2/SPRY.
FT {ECO:0000259|PROSITE:PS50188}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 360 467 ipfam:SPRY [T]
FT MYHIT 17 61 iprf:ZF_RING_2 [T]
FT MYHIT 101 142 ismart:BBOX [T]
FT MYHIT 358 479 ismart:SPRY [T]
FT MYHIT 308 353 ipfam:PRY [T]
FT MYHIT 17 60 ismart:RING [T]
FT MYHIT 32 41 ipat:ZF_RING_1 [T]
FT MYHIT 104 142 ipfam:zf-B_box [T]
FT MYHIT 101 142 iprf:ZF_BBOX [T]
FT MYHIT 288 479 iprf:B302_SPRY [T]
FT MYHIT 305 357 ismart:PRY [T]
SQ SEQUENCE 479 AA; 54946 MW; 2BE0D13EF6CF554F CRC64;
MATAGDSRGE LQKELVCSIC LDYFDDPVIL KCGHNFCRMC ILMHWEENGG DDVGYQCPEC
RMVFAKMSFT KNYLVKNLVD KLSDFDYLKT CRPSAPAKPV KMDGKCERHH EELKLYCHTD
RKPICVVCRE SRAHRHHDVA PVPEVVEDMK SELKLRLIKL NWQKSMCTRV KSTDEQAKTD
VKLKKQALKE KIEDDVGALV QFLLDEKDDL LERLEAEVVA TIGVIDANLK RVESEAAKVD
KAITEIQNQL SDSANFETIS NSYLSPCHVN LSVQSSNSPP DFSEFTGPFQ LIMWKKMMHV
LHTMPQNLTL DLDTAHPSLA ISDFDTKVEE GRVRSQEPDM PQRFTRFFGV LATAQYANGQ
HYWEVDVRDK GVWYLGVTTE YSNRKGFVNL SPSAGYWSLC LQDRLYANEE DSRVPVADYW
NSPRVGVFLD YDRGHVTFFD AVTMKRIYNF VTYFDEPVSP FFSPGKNDPG SRLQICHFY
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