ID Q7TRU7_MOUSE Unreviewed; 318 AA.
AC Q7TRU7;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 10-MAY-2017, entry version 101.
DE SubName: Full=Olfactory receptor 504 {ECO:0000313|Ensembl:ENSMUSP00000075025};
DE SubName: Full=Olfactory receptor Olfr504 {ECO:0000313|EMBL:AAP71003.1};
GN Name=Olfr504 {ECO:0000313|EMBL:AAP71003.1,
GN ECO:0000313|Ensembl:ENSMUSP00000075025, ECO:0000313|MGI:MGI:3030338};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000313|EMBL:AAP71003.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA Walker M., Williams E.M., Trask B.J.;
RT "Odorant receptor expressed sequence tags demonstrate olfactory
RT expression of over 400 genes, extensive alternate splicing and unequal
RT expression levels.";
RL Genome Biol. 4:R71.1-R71.13(2003).
RN [2] {ECO:0000313|EMBL:AAP71003.1}
RP NUCLEOTIDE SEQUENCE.
RA Sanders K.;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000075025, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000075025,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000075025}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000075025};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|SAAS:SAAS00521146}; Multi-pass membrane protein
CC {ECO:0000256|SAAS:SAAS00521146}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|SAAS:SAAS00591716}.
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DR EMBL; AC140274; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY317612; AAP71003.1; -; Genomic_DNA.
DR RefSeq; NP_001011858.1; NM_001011858.1.
DR UniGene; Mm.377367; -.
DR STRING; 10090.ENSMUSP00000075025; -.
DR Ensembl; ENSMUST00000075595; ENSMUSP00000075025; ENSMUSG00000060105.
DR GeneID; 258163; -.
DR KEGG; mmu:258163; -.
DR UCSC; uc009jco.1; mouse.
DR CTD; 258163; -.
DR MGI; MGI:3030338; Olfr504.
DR GeneTree; ENSGT00550000074576; -.
DR HOVERGEN; HBG017625; -.
DR OrthoDB; EOG091G0AZH; -.
DR TreeFam; TF344049; -.
DR Reactome; R-MMU-381753; Olfactory Signaling Pathway.
DR Proteomes; UP000000589; Chromosome 7.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|SAAS:SAAS00521172};
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW G-protein coupled receptor {ECO:0000256|SAAS:SAAS00529918};
KW Membrane {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAAS:SAAS00521172, ECO:0000256|SAM:Phobius};
KW Olfaction {ECO:0000256|SAAS:SAAS00521184};
KW Receptor {ECO:0000256|SAAS:SAAS00529918};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Sensory transduction {ECO:0000256|SAAS:SAAS00521184};
KW Transducer {ECO:0000256|SAAS:SAAS00529918};
KW Transmembrane {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35 55 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 67 93 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 105 126 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 146 169 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 207 228 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 249 269 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 275 298 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 47 296 G_PROTEIN_RECEP_F1_2.
FT {ECO:0000259|PROSITE:PS50262}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 47 296 iprf:G_PROTEIN_RECEP_F1_2 [T]
FT MYHIT 43 311 ismart:7TM_GPCR_Srsx [T]
SQ SEQUENCE 318 AA; 35577 MW; 875257F91A21A17C CRC64;
MSASLKDFNS SKFLVSEFIL LGFPGIHSWQ HWLSLPLTLL YLSAIGTNVL ILIIICQDPS
LKQPMYLFLG ILSLVDMGLA TTIMPKILAI FWFDAKVISL PECFAQIYAI HCFVSMESGI
CLCMAFDRYV AICYPLHYSS IITNSLIFKA TLFMVLRNGF CVISVPVLAS QWNYCSRNEI
DHCLCSNLGI TSLACDDRRP NSIFQLILAW VGMGSELGLI ILSYTLLLRS VLRLNSAEAV
SKALNTCSSH LILTLFYTVI VVISVTHLSE TKATLIPVLL NVMHNITPPS LNPIVYALRT
RQLRQGFQKV LCRSLQEK
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