MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
Description | SubName: Full=3-phosphoinositide-dependent protein kinase 1b {ECO:0000313|Ensembl:ENSDARP00000019085}; SubName: Full=Zgc:77318 {ECO:0000313|EMBL:AAH65959.1}; |
![]() |
|
MyHits synonyms | Q6NZV1_DANRE , Q6NZV1 , 20A0FED4E0A79D6F |
![]() Legends: 1, ipat:PROTEIN_KINASE_ATP [T]; 2, ipat:PROTEIN_KINASE_ST [T].
| |
ID Q6NZV1_DANRE Unreviewed; 537 AA. AC Q6NZV1; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 10-MAY-2017, entry version 120. DE SubName: Full=3-phosphoinositide-dependent protein kinase 1b {ECO:0000313|Ensembl:ENSDARP00000019085}; DE SubName: Full=Zgc:77318 {ECO:0000313|EMBL:AAH65959.1}; GN Name=pdpk1b {ECO:0000313|Ensembl:ENSDARP00000019085, GN ECO:0000313|ZFIN:ZDB-GENE-040426-1820}; GN Synonyms=zgc:77318 {ECO:0000313|EMBL:AAH65959.1}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH65959.1}; RN [1] {ECO:0000313|EMBL:AAH65959.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Embryo {ECO:0000313|EMBL:AAH65959.1}; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSDARP00000019085} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000019085}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [3] {ECO:0000313|Ensembl:ENSDARP00000019085, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000019085, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CU469584; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC065959; AAH65959.1; -; mRNA. DR RefSeq; NP_991262.1; NM_205699.1. DR UniGene; Dr.29812; -. DR STRING; 7955.ENSDARP00000019085; -. DR Ensembl; ENSDART00000003789; ENSDARP00000019085; ENSDARG00000018285. DR GeneID; 403000; -. DR KEGG; dre:403000; -. DR CTD; 403000; -. DR ZFIN; ZDB-GENE-040426-1820; pdpk1b. DR eggNOG; KOG0592; Eukaryota. DR eggNOG; ENOG410XRT8; LUCA. DR GeneTree; ENSGT00550000074819; -. DR HOGENOM; HOG000233026; -. DR HOVERGEN; HBG098357; -. DR KO; K06276; -. DR OMA; QENFTSH; -. DR OrthoDB; EOG091G06CX; -. DR TreeFam; TF105423; -. DR Reactome; R-DRE-114604; GPVI-mediated activation cascade. DR Reactome; R-DRE-1257604; PIP3 activates AKT signaling. DR Reactome; R-DRE-165158; Activation of AKT2. DR Reactome; R-DRE-202424; Downstream TCR signaling. DR Reactome; R-DRE-2730905; Role of LAT2/NTAL/LAB on calcium mobilization. DR Reactome; R-DRE-2871837; FCERI mediated NF-kB activation. DR Reactome; R-DRE-354192; Integrin alphaIIb beta3 signaling. DR Reactome; R-DRE-389357; CD28 dependent PI3K/Akt signaling. DR Reactome; R-DRE-392451; G beta:gamma signalling through PI3Kgamma. DR Reactome; R-DRE-444257; RSK activation. DR Reactome; R-DRE-5218920; VEGFR2 mediated vascular permeability. DR Reactome; R-DRE-5218921; VEGFR2 mediated cell proliferation. DR Reactome; R-DRE-5607764; CLEC7A (Dectin-1) signaling. DR Reactome; R-DRE-5625740; RHO GTPases activate PKNs. DR Reactome; R-DRE-6804757; Regulation of TP53 Degradation. DR Proteomes; UP000000437; Chromosome 24. DR Bgee; ENSDARG00000018285; -. DR GO; GO:0005622; C:intracellular; IBA:GO_Central. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central. DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central. DR GO; GO:0018105; P:peptidyl-serine phosphorylation; IBA:GO_Central. DR CDD; cd01262; PH_PDK1; 1. DR Gene3D; 2.30.29.30; -; 1. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR033931; PDK1-typ_PH. DR InterPro; IPR011993; PH_dom-like. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF14593; PH_3; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF50729; SSF50729; 2. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Proteomics identification {ECO:0000213|PeptideAtlas:Q6NZV1}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}. FT DOMAIN 60 320 Protein kinase. FT {ECO:0000259|PROSITE:PS50011}. CC -------------------------------------------------------------------------- CC The following FT lines are automated annotations from the MyHits database. CC -------------------------------------------------------------------------- FT MYHIT 66 89 ipat:PROTEIN_KINASE_ATP [T] FT MYHIT 428 528 ipfam:PH_3 [T] FT MYHIT 61 308 ipfam:Pkinase [T] FT MYHIT 60 320 ismart:S_TKc [T] FT MYHIT 179 191 ipat:PROTEIN_KINASE_ST [T] FT MYHIT 60 320 iprf:PROTEIN_KINASE_DOM [T] SQ SEQUENCE 537 AA; 61490 MW; 20A0FED4E0A79D6F CRC64; MARATSQIYD VASLHSSVLI SCPSMVRGQQ DTPRLHGNSM EGPAPNAQPA QPRKKRPEDF RFGKILGEGS FSTVVLAKEH TTGKEYAIKI LEKRHIMKEN KAQYVKRERD IMSHLDHPFF VKLYFTFQDE EKLYFGLSYA KNGELLKYIR KIGSFDETCT RFYSAEIVCA LEYLHQKGII HRDLKPENIL LSEEMHIQIT DFGTAKQLSS DSKQARANSF VGTAQYVSPE LLTEKSACKS SDLWALGCII YQLVAGLPPF RAGNEYLIFQ KIIKLEYEFP EKFFPKAKDL VEQLLSLDSC KRIGCDEMGG YGPLKSHPFF ESVGWDDLHL QTPPKLTAYL PAMSEDDEDC YGNYDDLLSQ FSCMQVAQPG PAPLVPVTGE TSQPTYNPSP SVDQFIHIHE LDSNSMELDL QYSNEEKRIL LDKQSAANPW HQFVENNLIL KMGPVDKRKG LFARRRQLLL TEGPHLYYVD PVNKVLKGEI PWSPELRPEA KNFKTFFVHT PNRTYYLMDP SGNADKWCKK IQEVWRKIYH KHQSPSL // |