Entry euk:Q6MGC7_RAT

ID   Q6MGC7_RAT              Unreviewed;       636 AA.
AC   Q6MGC7;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   10-MAY-2017, entry version 119.
DE   SubName: Full=RCG61041, isoform CRA_a {ECO:0000313|EMBL:EDL96852.1};
DE   SubName: Full=Zinc finger and BTB domain containing 22 {ECO:0000313|EMBL:AAH95905.1};
DE   SubName: Full=Zinc finger and BTB domain-containing 22 {ECO:0000313|Ensembl:ENSRNOP00000000558};
DE   SubName: Full=Zinc finger protein 297 {ECO:0000313|EMBL:CAE83919.1};
GN   Name=Zbtb22 {ECO:0000313|EMBL:AAH95905.1,
GN   ECO:0000313|Ensembl:ENSRNOP00000000558, ECO:0000313|RGD:1359627};
GN   Synonyms=AA926063 {ECO:0000313|RGD:1359627},
GN   B3galt4 {ECO:0000313|RGD:1359627},
GN   Cdk2ap1-ps1 {ECO:0000313|RGD:1359627},
GN   Col11a2 {ECO:0000313|RGD:1359627}, Daxx {ECO:0000313|RGD:1359627},
GN   Hsd17b8 {ECO:0000313|RGD:1359627}, Kifc1 {ECO:0000313|RGD:1359627},
GN   LOC224733l-1 {ECO:0000313|RGD:1359627},
GN   LOC224733l-2 {ECO:0000313|RGD:1359627},
GN   Phf1 {ECO:0000313|RGD:1359627}, Rps25-ps1 {ECO:0000313|RGD:1359627},
GN   RT1-A1 {ECO:0000313|RGD:1359627}, RT1-A2 {ECO:0000313|RGD:1359627},
GN   RT1-A3 {ECO:0000313|RGD:1359627}, RT1-DOa {ECO:0000313|RGD:1359627},
GN   RT1-Hb {ECO:0000313|RGD:1359627}, RT1-Ke4 {ECO:0000313|RGD:1359627},
GN   Rxrb {ECO:0000313|RGD:1359627}, Sacm2l-ps1 {ECO:0000313|RGD:1359627},
GN   Sacm2l-ps2 {ECO:0000313|RGD:1359627},
GN   Sec61-ps {ECO:0000313|RGD:1359627}, Syngap1 {ECO:0000313|RGD:1359627},
GN   Znf297 {ECO:0000313|EMBL:CAE83919.1};
GN   ORFNames=rCG_61041 {ECO:0000313|EMBL:EDL96852.1};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1] {ECO:0000313|EMBL:CAE83919.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brown Norway {ECO:0000313|EMBL:CAE83919.1};
RA   Boehm S., Borzym K., Gelling S., Gimmel V., Heitmann K., Kosiura A.,
RA   Lang N., Lehrack S., Thiel J., Sontag M., Hurt P., Himmelbauer H.,
RA   Sudbrak R., Reinhardt R.;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAE83919.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brown Norway {ECO:0000313|EMBL:CAE83919.1};
RX   PubMed=15060004; DOI=10.1101/gr.1987704;
RA   Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T.,
RA   Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT   "The genomic sequence and comparative analysis of the rat major
RT   histocompatibility complex.";
RL   Genome Res. 14:631-639(2004).
RN   [3] {ECO:0000313|EMBL:AAH95905.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis {ECO:0000313|EMBL:AAH95905.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA   Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA   Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA   Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA   Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA   Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA   Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA   Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA   Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA   Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA   Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA   Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA   Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA   Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA   Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA   Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA   Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA   Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA   Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4] {ECO:0000313|Ensembl:ENSRNOP00000000558, ECO:0000313|Proteomes:UP000002494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000000558,
RC   ECO:0000313|Proteomes:UP000002494};
RX   PubMed=15057822; DOI=10.1038/nature02426;
RG   Rat Genome Sequencing Project Consortium;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA   Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA   Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA   Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA   Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA   Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA   Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA   Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA   Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA   D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA   Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA   Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA   Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA   Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA   Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA   Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA   Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA   Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA   Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA   Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA   Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA   Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA   Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA   Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA   Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA   Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA   Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA   Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA   Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA   Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA   Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA   Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA   Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA   Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA   Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into
RT   mammalian evolution.";
RL   Nature 428:493-521(2004).
RN   [5] {ECO:0000313|EMBL:EDL96852.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BN {ECO:0000313|EMBL:EDL96852.1};
RX   PubMed=15632090; DOI=10.1101/gr.2889405;
RA   Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M.,
RA   Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z.,
RA   Istrail S., Li P., Sutton G.;
RT   "Gene and alternative splicing annotation with AIR.";
RL   Genome Res. 15:54-66(2005).
RN   [6] {ECO:0000313|EMBL:EDL96852.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BN {ECO:0000313|EMBL:EDL96852.1};
RA   Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H.,
RA   Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M.,
RA   Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L.,
RA   Lu F., Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C.,
RA   Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000213|PubMed:22673903}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A.,
RA   Lundby C., Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14
RT   different rat organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
RN   [8] {ECO:0000313|Ensembl:ENSRNOP00000000558}
RP   IDENTIFICATION.
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000000558};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC128962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC095905; AAH95905.1; -; mRNA.
DR   EMBL; BX883042; CAE83919.1; -; Genomic_DNA.
DR   EMBL; CH473988; EDL96852.1; -; Genomic_DNA.
DR   RefSeq; NP_001009172.1; NM_001009172.3.
DR   RefSeq; XP_006256185.1; XM_006256123.3.
DR   RefSeq; XP_017457130.1; XM_017601641.1.
DR   UniGene; Rn.17135; -.
DR   STRING; 10116.ENSRNOP00000000558; -.
DR   Ensembl; ENSRNOT00000000558; ENSRNOP00000000558; ENSRNOG00000000476.
DR   GeneID; 309630; -.
DR   KEGG; rno:309630; -.
DR   UCSC; RGD:1359627; rat.
DR   CTD; 9278; -.
DR   RGD; 1359627; Zbtb22.
DR   eggNOG; KOG1721; Eukaryota.
DR   eggNOG; COG5048; LUCA.
DR   GeneTree; ENSGT00760000119063; -.
DR   HOGENOM; HOG000231975; -.
DR   HOVERGEN; HBG056510; -.
DR   KO; K10502; -.
DR   OMA; VEMGFSG; -.
DR   OrthoDB; EOG091G06Z9; -.
DR   PRO; PR:Q6MGC7; -.
DR   Proteomes; UP000002494; Chromosome 20.
DR   Bgee; ENSRNOG00000000476; -.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR029833; ZBT22.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24414:SF46; PTHR24414:SF46; 1.
DR   Pfam; PF00651; BTB; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT   DOMAIN       57    121       BTB (POZ). {ECO:0000259|PROSITE:PS50097}.
FT   DOMAIN      483    509       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      510    537       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      538    564       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT       510    537       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       512    532       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       538    564       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT        57    151       ismart:BTB [T]
FT   MYHIT        57    121       iprf:BTB [T]
FT   MYHIT       483    504       ismart:ZnF_C2H2 [T]
FT   MYHIT       510    532       ismart:ZnF_C2H2 [T]
FT   MYHIT        47    149       ipfam:BTB [T]
FT   MYHIT       538    559       ismart:ZnF_C2H2 [T]
FT   MYHIT       483    509       iprf:ZINC_FINGER_C2H2_2 [T]
SQ   SEQUENCE   636 AA;  65835 MW;  EDF799938726DABF CRC64;
     MEPSPMSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS
     IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA
     AADIVNFLTV GSVLQMWHIV DKCTELLREG RSSAATTTVT AVAAPSVSVP CASVPSGSGG
     TVAPATVGSV RSHTSSRASE NQSPSSSNYF SPRESTDFSS SSQDAFVASA VGSGNRRDGG
     PVFPVPVVGS AGTTSGKLLL EADELCDDGG DGRGAAAPGA GLRRPNCLPA SAVPQKHWVY
     VKRARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDED LGNGSGVPAG GEPEATLSIS
     DVRTLTEPAE KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP GGPTPSSYGL THPPRPLLPL
     DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA VTLGGASAVG LGIPSGSGGT PGGAGNSDGN
     KIFLCHCGKA FSHKSMRDRH VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC
     SVCAKKFMWR DSFMRHRGHC ERRHRMGAGG AASVPGPGPG APTGPALQPK RESSAVGGGS
     GDEANSATPP SNRRVWSPPS VHKVEMDFSG GGGAAH
//