ID Q6MGC7_RAT Unreviewed; 636 AA.
AC Q6MGC7;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 10-MAY-2017, entry version 119.
DE SubName: Full=RCG61041, isoform CRA_a {ECO:0000313|EMBL:EDL96852.1};
DE SubName: Full=Zinc finger and BTB domain containing 22 {ECO:0000313|EMBL:AAH95905.1};
DE SubName: Full=Zinc finger and BTB domain-containing 22 {ECO:0000313|Ensembl:ENSRNOP00000000558};
DE SubName: Full=Zinc finger protein 297 {ECO:0000313|EMBL:CAE83919.1};
GN Name=Zbtb22 {ECO:0000313|EMBL:AAH95905.1,
GN ECO:0000313|Ensembl:ENSRNOP00000000558, ECO:0000313|RGD:1359627};
GN Synonyms=AA926063 {ECO:0000313|RGD:1359627},
GN B3galt4 {ECO:0000313|RGD:1359627},
GN Cdk2ap1-ps1 {ECO:0000313|RGD:1359627},
GN Col11a2 {ECO:0000313|RGD:1359627}, Daxx {ECO:0000313|RGD:1359627},
GN Hsd17b8 {ECO:0000313|RGD:1359627}, Kifc1 {ECO:0000313|RGD:1359627},
GN LOC224733l-1 {ECO:0000313|RGD:1359627},
GN LOC224733l-2 {ECO:0000313|RGD:1359627},
GN Phf1 {ECO:0000313|RGD:1359627}, Rps25-ps1 {ECO:0000313|RGD:1359627},
GN RT1-A1 {ECO:0000313|RGD:1359627}, RT1-A2 {ECO:0000313|RGD:1359627},
GN RT1-A3 {ECO:0000313|RGD:1359627}, RT1-DOa {ECO:0000313|RGD:1359627},
GN RT1-Hb {ECO:0000313|RGD:1359627}, RT1-Ke4 {ECO:0000313|RGD:1359627},
GN Rxrb {ECO:0000313|RGD:1359627}, Sacm2l-ps1 {ECO:0000313|RGD:1359627},
GN Sacm2l-ps2 {ECO:0000313|RGD:1359627},
GN Sec61-ps {ECO:0000313|RGD:1359627}, Syngap1 {ECO:0000313|RGD:1359627},
GN Znf297 {ECO:0000313|EMBL:CAE83919.1};
GN ORFNames=rCG_61041 {ECO:0000313|EMBL:EDL96852.1};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1] {ECO:0000313|EMBL:CAE83919.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brown Norway {ECO:0000313|EMBL:CAE83919.1};
RA Boehm S., Borzym K., Gelling S., Gimmel V., Heitmann K., Kosiura A.,
RA Lang N., Lehrack S., Thiel J., Sontag M., Hurt P., Himmelbauer H.,
RA Sudbrak R., Reinhardt R.;
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAE83919.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brown Norway {ECO:0000313|EMBL:CAE83919.1};
RX PubMed=15060004; DOI=10.1101/gr.1987704;
RA Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T.,
RA Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT "The genomic sequence and comparative analysis of the rat major
RT histocompatibility complex.";
RL Genome Res. 14:631-639(2004).
RN [3] {ECO:0000313|EMBL:AAH95905.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis {ECO:0000313|EMBL:AAH95905.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4] {ECO:0000313|Ensembl:ENSRNOP00000000558, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000000558,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into
RT mammalian evolution.";
RL Nature 428:493-521(2004).
RN [5] {ECO:0000313|EMBL:EDL96852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BN {ECO:0000313|EMBL:EDL96852.1};
RX PubMed=15632090; DOI=10.1101/gr.2889405;
RA Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M.,
RA Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z.,
RA Istrail S., Li P., Sutton G.;
RT "Gene and alternative splicing annotation with AIR.";
RL Genome Res. 15:54-66(2005).
RN [6] {ECO:0000313|EMBL:EDL96852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BN {ECO:0000313|EMBL:EDL96852.1};
RA Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H.,
RA Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M.,
RA Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L.,
RA Lu F., Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C.,
RA Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000213|PubMed:22673903}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A.,
RA Lundby C., Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14
RT different rat organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
RN [8] {ECO:0000313|Ensembl:ENSRNOP00000000558}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000000558};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR EMBL; AC128962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC095905; AAH95905.1; -; mRNA.
DR EMBL; BX883042; CAE83919.1; -; Genomic_DNA.
DR EMBL; CH473988; EDL96852.1; -; Genomic_DNA.
DR RefSeq; NP_001009172.1; NM_001009172.3.
DR RefSeq; XP_006256185.1; XM_006256123.3.
DR RefSeq; XP_017457130.1; XM_017601641.1.
DR UniGene; Rn.17135; -.
DR STRING; 10116.ENSRNOP00000000558; -.
DR Ensembl; ENSRNOT00000000558; ENSRNOP00000000558; ENSRNOG00000000476.
DR GeneID; 309630; -.
DR KEGG; rno:309630; -.
DR UCSC; RGD:1359627; rat.
DR CTD; 9278; -.
DR RGD; 1359627; Zbtb22.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119063; -.
DR HOGENOM; HOG000231975; -.
DR HOVERGEN; HBG056510; -.
DR KO; K10502; -.
DR OMA; VEMGFSG; -.
DR OrthoDB; EOG091G06Z9; -.
DR PRO; PR:Q6MGC7; -.
DR Proteomes; UP000002494; Chromosome 20.
DR Bgee; ENSRNOG00000000476; -.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ.
DR InterPro; IPR029833; ZBT22.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24414:SF46; PTHR24414:SF46; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF54695; SSF54695; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT DOMAIN 57 121 BTB (POZ). {ECO:0000259|PROSITE:PS50097}.
FT DOMAIN 483 509 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 510 537 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 538 564 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 483 509 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 510 537 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 47 149 ipfam:BTB [T]
FT MYHIT 538 564 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 57 151 ismart:BTB [T]
FT MYHIT 512 532 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 57 121 iprf:BTB [T]
FT MYHIT 538 559 ismart:ZnF_C2H2 [T]
FT MYHIT 483 504 ismart:ZnF_C2H2 [T]
FT MYHIT 510 532 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 636 AA; 65835 MW; EDF799938726DABF CRC64;
MEPSPMSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS
IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA
AADIVNFLTV GSVLQMWHIV DKCTELLREG RSSAATTTVT AVAAPSVSVP CASVPSGSGG
TVAPATVGSV RSHTSSRASE NQSPSSSNYF SPRESTDFSS SSQDAFVASA VGSGNRRDGG
PVFPVPVVGS AGTTSGKLLL EADELCDDGG DGRGAAAPGA GLRRPNCLPA SAVPQKHWVY
VKRARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDED LGNGSGVPAG GEPEATLSIS
DVRTLTEPAE KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP GGPTPSSYGL THPPRPLLPL
DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA VTLGGASAVG LGIPSGSGGT PGGAGNSDGN
KIFLCHCGKA FSHKSMRDRH VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC
SVCAKKFMWR DSFMRHRGHC ERRHRMGAGG AASVPGPGPG APTGPALQPK RESSAVGGGS
GDEANSATPP SNRRVWSPPS VHKVEMDFSG GGGAAH
//
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