ID Q6DH50_DANRE Unreviewed; 264 AA.
AC Q6DH50;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 10-MAY-2017, entry version 105.
DE SubName: Full=Hepatitis A virus cellular receptor 1 {ECO:0000313|Ensembl:ENSDARP00000058773};
DE SubName: Full=Kidney injury molecule 1 {ECO:0000313|EMBL:ABP97434.1};
DE SubName: Full=Zgc:92647 {ECO:0000313|EMBL:AAH76132.1};
GN Name=havcr1 {ECO:0000313|Ensembl:ENSDARP00000058773,
GN ECO:0000313|ZFIN:ZDB-GENE-040718-131};
GN Synonyms=kim1 {ECO:0000313|EMBL:ABP97434.1},
GN zgc:92647 {ECO:0000313|EMBL:AAH76132.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH76132.1};
RN [1] {ECO:0000313|EMBL:AAH76132.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye {ECO:0000313|EMBL:AAH76132.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP97434.1}
RP NUCLEOTIDE SEQUENCE.
RA Kuehn E.W., Putz M., Walz G., Kramer-Zucker A.;
RT "Kidney injury molecule 1 (Kim1) is a novel ciliary receptor and
RT interactor of polycystin 2.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAP71916.1}
RP NUCLEOTIDE SEQUENCE.
RA Martin S.and.Wright.G.J.;
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSDARP00000058773}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000058773};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [5] {ECO:0000313|Ensembl:ENSDARP00000058773, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000058773,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
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DR EMBL; CU463029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC076132; AAH76132.1; -; mRNA.
DR EMBL; EF437151; ABP97434.1; -; mRNA.
DR EMBL; CU638767; CAP71916.1; -; mRNA.
DR RefSeq; NP_001002434.1; NM_001002434.1.
DR UniGene; Dr.29795; -.
DR Ensembl; ENSDART00000058774; ENSDARP00000058773; ENSDARG00000040178.
DR GeneID; 436707; -.
DR KEGG; dre:436707; -.
DR CTD; 26762; -.
DR ZFIN; ZDB-GENE-040718-131; havcr1.
DR GeneTree; ENSGT00440000039800; -.
DR HOGENOM; HOG000206336; -.
DR TreeFam; TF336163; -.
DR Proteomes; UP000000437; Chromosome 21.
DR Bgee; ENSDARG00000040178; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1 22 {ECO:0000256|SAM:SignalP}.
FT CHAIN 23 264 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5010141697.
FT TRANSMEM 190 210 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 31 113 Ig-like (immunoglobulin-like).
FT {ECO:0000259|PROSITE:PS50835}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 31 130 ipfam:V-set [T]
FT MYHIT 24 131 ismart:IG [T]
FT MYHIT 31 113 iprf:IG_LIKE [T]
SQ SEQUENCE 264 AA; 29575 MW; 5674E3CF069D1AB0 CRC64;
MTDLHSWFLS SWILCCLTIC RCSDIIVQSF EGDNVTLPCK YDSRYHGKCE ICWMRGDIPS
RGCGEEIIAS DGDKVSTRNS DRYDLAGPIQ HGDVSLTIFN IDKTDSGKYG CRVHVPGWFN
DEKYYVHLIV DDDNKTRKEI SSTISPSYAP RSSTAGMWLS NTTSVEPSVS VVYHESSSAE
SKDNVTVSAV LVPVLLLLLA LIAIAAAFMW KQKKKTRASL EVRQNSEISV IYSNSGSSVG
LYNREMAVEN VYQIQAESEY EQWH
//
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