ID Q68EI2_DANRE Unreviewed; 986 AA.
AC Q68EI2;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 10-MAY-2017, entry version 111.
DE SubName: Full=PHD finger protein 20, b {ECO:0000313|Ensembl:ENSDARP00000056569};
DE SubName: Full=Zgc:91986 {ECO:0000313|EMBL:AAH80250.1};
GN Name=phf20b {ECO:0000313|Ensembl:ENSDARP00000056569,
GN ECO:0000313|ZFIN:ZDB-GENE-040822-33};
GN Synonyms=zgc:91986 {ECO:0000313|EMBL:AAH80250.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH80250.1};
RN [1] {ECO:0000313|EMBL:AAH80250.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH80250.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000056569}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000056569};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000056569, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000056569,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
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DR EMBL; CR352242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC080250; AAH80250.1; -; mRNA.
DR RefSeq; NP_001004114.1; NM_001004114.1.
DR UniGene; Dr.2818; -.
DR STRING; 7955.ENSDARP00000112091; -.
DR Ensembl; ENSDART00000056570; ENSDARP00000056569; ENSDARG00000038737.
DR GeneID; 445482; -.
DR KEGG; dre:445482; -.
DR CTD; 445482; -.
DR ZFIN; ZDB-GENE-040822-33; phf20b.
DR eggNOG; KOG1844; Eukaryota.
DR eggNOG; ENOG410XX7Z; LUCA.
DR GeneTree; ENSGT00390000006451; -.
DR HOGENOM; HOG000231997; -.
DR HOVERGEN; HBG053586; -.
DR KO; K18402; -.
DR TreeFam; TF106475; -.
DR Reactome; R-DRE-3214847; HATs acetylate histones.
DR Reactome; R-DRE-6804759; Regulation of TP53 Activity through Association with Co-factors.
DR Proteomes; UP000000437; Chromosome 23.
DR Bgee; ENSDARG00000038737; -.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF02820; MBT; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF57903; SSF57903; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Metal-binding {ECO:0000256|SAAS:SAAS00592111};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Zinc {ECO:0000256|SAAS:SAAS00592111};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00592111}.
FT DOMAIN 421 451 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 421 451 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 618 662 ismart:PHD [T]
FT MYHIT 619 661 ipat:ZF_PHD_1 [T]
FT MYHIT 19 68 ipfam:MBT [T]
FT MYHIT 85 141 ismart:TUDOR [T]
FT MYHIT 423 446 ipat:ZINC_FINGER_C2H2_1 [T]
SQ SEQUENCE 986 AA; 112865 MW; 8C33AFB443445232 CRC64;
MTKSPPNRRG IVFEVGAQLE ARDTLKNWYA ANIEKIDYED EKVLIHYRQW SHRYDEWFDW
SSPYLRPVER IQLRKQGLNE RQCASGFQVN QKVLASWSDC RYYPAKILSR DKDDFYTVKF
FDGIIKTVKG IKVKPFRKQS SDGRSNQQAR KRADQNEKEL KPKENGNSRH NSSRHSVSDH
DGESESEADE DTTVMDESTD LQNGGEKEST ETKMVNDSEV SSAEHQPSED QNQPSEDKTE
NLENGNVEIK IEEEEEEEMD GGQEEAKVLH NGIDKNDEHK GEASDESPSL PKRTRSRTAD
GKEAEMVNGP ELRKRRASTG QTSPAKRSRA NSSTDRNTQT PIKPVKSDSV PDTLDIKDEK
TSPAGKPAPA EEAGSTPELA AALKRQVHLP TTNKYSREPL YRVIKNQPPP ILSIELDHNP
FKCKMAGCLK SFRKASLLHY HMKYYHAQSD PSPPRCVQTR SSDKQSPSQE TPRRRRTVSA
SHHTPSPLSD SKSGHSLSPP AVGIKHRQRS ATLGAERSKE NQVFNRSLHD DRDWVAKETA
LKERERLREK RQREFFRIKL KKKKKKKRKS KSGEDSSSDL SSDSPVWSED ESDTELDLNV
PLSEQGVETV THSSEIVRCI CEVQEENDFM IQCDECLCWQ HGTCMGLYED SVPDSYSCYI
CRDPPAQRQS QRYWYDKDWL SSGHMYGLSF LEENYSHQNS KKVTAAHQLL GDVHRVFEVL
NGLQLKMSIL QTQAHPDLKL WRQPWKHADG LRRRMAGDSG IATPLPPSPP EMGENEFETL
KSEAPSPMET HCSFQDSYIS SEHCYQKPRT YYPAVERRLV VETRGGSELE DSLRSTEDLL
EMAEQRYGTQ LDHDQHKLAD RSFSKELESR MKRLVSAEQE KSCGVEIKEE EPDPVTPDPK
PDPDLVLHQQ WQLNLLEHIE AVQDEVTHRM DLIERELDVL ESWLDYTGEL EPPDPLARLP
QLKHRIRQLL TDLGTVQQIA LCSSSS
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