Entry euk:Q66IA7_DANRE

ID   Q66IA7_DANRE            Unreviewed;       155 AA.
AC   Q66IA7;
DT   11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   11-OCT-2004, sequence version 1.
DT   10-MAY-2017, entry version 86.
DE   SubName: Full=Ubiquitously-expressed, prefoldin-like chaperone {ECO:0000313|Ensembl:ENSDARP00000020173};
DE   SubName: Full=Zgc:101894 {ECO:0000313|EMBL:AAH81425.1};
GN   Name=uxt {ECO:0000313|Ensembl:ENSDARP00000020173,
GN   ECO:0000313|ZFIN:ZDB-GENE-040912-118};
GN   Synonyms=zgc:101894 {ECO:0000313|EMBL:AAH81425.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH81425.1};
RN   [1] {ECO:0000313|EMBL:AAH81425.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Larvae {ECO:0000313|EMBL:AAH81425.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000020173}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000020173};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000020173, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000020173,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CR356245; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC081425; AAH81425.1; -; mRNA.
DR   RefSeq; NP_001004671.1; NM_001004671.1.
DR   UniGene; Dr.90415; -.
DR   STRING; 7955.ENSDARP00000020173; -.
DR   DNASU; 447933; -.
DR   Ensembl; ENSDART00000021209; ENSDARP00000020173; ENSDARG00000019339.
DR   GeneID; 447933; -.
DR   KEGG; dre:447933; -.
DR   CTD; 8409; -.
DR   ZFIN; ZDB-GENE-040912-118; uxt.
DR   eggNOG; KOG3047; Eukaryota.
DR   eggNOG; ENOG4111Q3P; LUCA.
DR   GeneTree; ENSGT00390000018078; -.
DR   HOGENOM; HOG000005748; -.
DR   HOVERGEN; HBG001087; -.
DR   OMA; NIFMQAR; -.
DR   OrthoDB; EOG091G0UOM; -.
DR   TreeFam; TF323827; -.
DR   Proteomes; UP000000437; Chromosome 8.
DR   Bgee; ENSDARG00000019339; -.
DR   GO; GO:0000785; C:chromatin; IDA:ZFIN.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IBA:GO_Central.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IMP:ZFIN.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:ZFIN.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR011599; PFD_alpha_archaea.
DR   InterPro; IPR004127; Prefoldin_subunit_alpha.
DR   InterPro; IPR003994; UXT.
DR   Pfam; PF02996; Prefoldin; 1.
DR   PRINTS; PR01502; UXTPROTEIN.
DR   TIGRFAMs; TIGR00293; TIGR00293; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q66IA7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        25    141       ipfam:Prefoldin [T]
SQ   SEQUENCE   155 AA;  17868 MW;  B502972439C9D3C4 CRC64;
     MTSGTSVIND KVLQYETFIS EVLRRDLQKV LEQRDAVYEK IAQYLQLKNT IQSIQESGSK
     ELKTDVDLGC NFYVQAHVPD ASRIYVAVGY GFFVEFTHAE ALKFIEKKTN QLTEYTEVLT
     KDAAKIKANI RMVLEGLREL QGLKDLPEDR RREVF
//