ID Q5KPN8_CRYNJ Unreviewed; 219 AA.
AC Q5KPN8;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 10-MAY-2017, entry version 83.
DE SubName: Full=Vesicle-associated membrane protein 712, putative {ECO:0000313|EMBL:AAW40773.2};
GN OrderedLocusNames=CNA02090 {ECO:0000313|EMBL:AAW40773.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /
OS ATCC MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW40773.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW40773.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J.,
RA D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J.,
RA Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I.,
RA Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E.,
RA Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L.,
RA Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A.,
RA Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R.,
RA Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W.,
RA Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen
RT Cryptococcus neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|SAAS:SAAS00810078}.
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DR EMBL; AE017341; AAW40773.2; -; Genomic_DNA.
DR RefSeq; XP_566592.1; XM_566592.1.
DR UniGene; Fne.7818; -.
DR ProteinModelPortal; Q5KPN8; -.
DR STRING; 214684.XP_566592.1; -.
DR PaxDb; Q5KPN8; -.
DR EnsemblFungi; AAW40773; AAW40773; CNA02090.
DR GeneID; 3253707; -.
DR KEGG; cne:CNA02090; -.
DR EuPathDB; FungiDB:CNA02090; -.
DR eggNOG; KOG0859; Eukaryota.
DR eggNOG; COG5143; LUCA.
DR HOGENOM; HOG000208972; -.
DR InParanoid; Q5KPN8; -.
DR KO; K08515; -.
DR OrthoDB; EOG092C4MCV; -.
DR Proteomes; UP000002149; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR InterPro; IPR011012; Longin-like_dom.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR001388; Synaptobrevin.
DR Pfam; PF13774; Longin; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR PRINTS; PR00219; SYNAPTOBREVN.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SSF64356; 1.
DR PROSITE; PS50859; LONGIN; 1.
DR PROSITE; PS00417; SYNAPTOBREVIN; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAAS:SAAS00119457};
KW Complete proteome {ECO:0000313|Proteomes:UP000002149};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 190 214 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 7 111 Longin. {ECO:0000259|PROSITE:PS50859}.
FT DOMAIN 126 186 V-SNARE coiled-coil homology.
FT {ECO:0000259|PROSITE:PS50892}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 7 111 iprf:LONGIN [T]
FT MYHIT 29 110 ismart:Longin [T]
FT MYHIT 144 163 ipat:SYNAPTOBREVIN [T]
FT MYHIT 32 108 ipfam:Longin [T]
FT MYHIT 126 186 iprf:V_SNARE [T]
FT MYHIT 125 211 ipfam:Synaptobrevin [T]
SQ SEQUENCE 219 AA; 24490 MW; A92B15BAD44E4CFB CRC64;
MSLIHALIAR GTTVLAEHAT GTAELKPAAQ ITILSKIPPN NSKLTYVWQD RLIHYVSSNG
VIYLVMADDS VGRRMPFAFL ADLERRFTAQ YESDDIVSAG AHSLEEFEPE LAKLMHQYTS
SPPADPLRQA QSDLNNVKDI MVQNIDSILQ RGERLDLLVD KTDTLAGQAY AFRRGARSVR
RQQWWKNMRI MALSGVVGLL LLYLFIAQFC GASLGHCRS
//
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