Entry euk:Q57W77_TRYB2

ID   Q57W77_TRYB2            Unreviewed;       554 AA.
AC   Q57W77; D6XL31;
DT   10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2005, sequence version 1.
DT   10-MAY-2017, entry version 57.
DE   RecName: Full=Probable methyltransferase BMT2 homolog {ECO:0000256|HAMAP-Rule:MF_03044};
DE            EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03044};
GN   ORFNames=Tb927.8.2960 {ECO:0000313|EMBL:AAX70142.1};
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431 {ECO:0000313|Proteomes:UP000008524};
RN   [1] {ECO:0000313|EMBL:AAZ13061.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13061.1};
RX   PubMed=16020724; DOI=10.1126/science.1112181;
RA   El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA   Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA   Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA   Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA   Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA   Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA   Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J.,
RA   Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S.,
RA   White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D.,
RA   Hall N.;
RT   "Comparative genomics of trypanosomatid parasitic protozoa.";
RL   Science 309:404-409(2005).
RN   [2] {ECO:0000313|EMBL:AAZ13061.1, ECO:0000313|Proteomes:UP000008524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13061.1,
RC   ECO:0000313|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B.,
RA   Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L.,
RA   Wickstead B., Alsmark U.C.M., Arrowsmith C., Atkin R.J., Barron A.J.,
RA   Bringaud F., Brooks K., Carrington M., Cherevach I.,
RA   Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A.,
RA   Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C.,
RA   Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H.,
RA   Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K.,
RA   Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V.,
RA   Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M.,
RA   Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S.,
RA   Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A.,
RA   Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B.,
RA   White O., Whitehead S., Woodward J., Wortman J., Adams M.D.,
RA   Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H.,
RA   Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M.,
RA   Melville S.E., El-Sayed N.M.A.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
RN   [3] {ECO:0000313|EMBL:AAX70142.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX70142.1};
RA   Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA   Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J.,
RA   Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J.,
RA   Khalak H.G., Salzberg S., Simpson A.J., Tallon L., Van Aken S.,
RA   Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable S-adenosyl-L-methionine-dependent
CC       methyltransferase. {ECO:0000256|HAMAP-Rule:MF_03044}.
CC   -!- SIMILARITY: Belongs to the BMT2 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03044}.
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DR   EMBL; AC159431; AAX70142.1; -; Genomic_DNA.
DR   EMBL; CP000071; AAZ13061.1; -; Genomic_DNA.
DR   RefSeq; XP_847127.1; XM_842034.1.
DR   EnsemblProtists; AAZ13061; AAZ13061; Tb927.8.2960.
DR   GeneDB; Tb927.8.2960:pep; -.
DR   GeneID; 3659294; -.
DR   KEGG; tbr:Tb927.8.2960; -.
DR   EuPathDB; TriTrypDB:Tb927.8.2960; -.
DR   Proteomes; UP000008524; Chromosome 8.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0016433; F:rRNA (adenine) methyltransferase activity; IBA:GO_Central.
DR   HAMAP; MF_03044; BMT2; 1.
DR   InterPro; IPR021867; Bmt2.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PANTHER; PTHR21008; PTHR21008; 1.
DR   SUPFAM; SSF53335; SSF53335; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008524};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_03044}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        32    542       ihamap:BMT2 [T]
SQ   SEQUENCE   554 AA;  60745 MW;  BD7E58785E68B7FB CRC64;
     MGGNRRHMGS IPGKSDVGEP GADLPPAPPV DLCDDQLRMA STIKSFHYKL QQRMTTAGDR
     TCTQETEEER WFRLIAEESE QMKSYTAAMH GIATQYWDPQ EDKLRDGGQT KSCVTCPPIT
     TRVIPSNDAI CVTKRVRDTE TVVVGSACER QRAACLRHND RIKYSLQCVT EYFLGICRVP
     PLIASGDTNR STCSEVADVL SCSAVAGAVY YEKLPLLASS SVKRWRRTYY DTHGRQAYPY
     EIDAEAYRVL LASERTVRDG NTAAPVCPLS SSGLVTTGTA GGTAANYMTM SRTEACRRIN
     LDCPHPRLLG QQRVPPLLVL DIGSCYGPFG GRIVTNGVLQ VPLAVTALDL SPYEGSGVIK
     ADWLAIRFHD SDGATGRCSC DDEGCISGTT FDDHGHADCG VSLVRWCDEE SGKYEGTGSA
     RRILSLARGA FDVVFFCLLL SFLPHPRLRY RACLHAYLAL KDGGLLVIVS TRTQGARRSL
     WVDEWIKCIE GIGFKRVHKN VMKQIVGLSF SKQPASEVSG DDSVLCGAEA WVERMMNRAD
     ALGGLRTIGD ESPW
//