ID Q566P1_DANRE Unreviewed; 267 AA.
AC Q566P1; U3JA45;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 10-MAY-2017, entry version 112.
DE SubName: Full=C1q and tumor necrosis factor-related protein 1 {ECO:0000313|Ensembl:ENSDARP00000127110};
DE SubName: Full=Zgc:113062 {ECO:0000313|EMBL:AAH93423.1};
GN Name=c1qtnf1 {ECO:0000313|Ensembl:ENSDARP00000127110,
GN ECO:0000313|ZFIN:ZDB-GENE-050417-427};
GN Synonyms=zgc:113062 {ECO:0000313|EMBL:AAH93423.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH93423.1};
RN [1] {ECO:0000313|EMBL:AAH93423.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Singapore local strain {ECO:0000313|EMBL:AAH93423.1};
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH93423.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000127110, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000127110,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|Ensembl:ENSDARP00000127110}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000127110};
RG Ensembl;
RL Submitted (SEP-2013) to UniProtKB.
RN [4] {ECO:0000313|Ensembl:ENSDARP00000131922}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000131922};
RG Ensembl;
RL Submitted (NOV-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00588336}.
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DR EMBL; BX936416; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01005449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01005450; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CR932358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CU595936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; FP236187; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; FP245468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC093423; AAH93423.1; -; mRNA.
DR RefSeq; NP_001017875.1; NM_001017875.2.
DR UniGene; Dr.43046; -.
DR STRING; 7955.ENSDARP00000108101; -.
DR Ensembl; ENSDART00000152908; ENSDARP00000127110; ENSDARG00000088878.
DR Ensembl; ENSDART00000162483; ENSDARP00000131922; ENSDARG00000088878.
DR GeneID; 550573; -.
DR KEGG; dre:550573; -.
DR CTD; 114897; -.
DR ZFIN; ZDB-GENE-050417-427; c1qtnf1.
DR eggNOG; ENOG410IKX5; Eukaryota.
DR eggNOG; ENOG410XQIM; LUCA.
DR GeneTree; ENSGT00760000118830; -.
DR HOGENOM; HOG000101544; -.
DR HOVERGEN; HBG108220; -.
DR OMA; LRCCDPG; -.
DR OrthoDB; EOG091G0LRA; -.
DR TreeFam; TF329591; -.
DR Proteomes; UP000000437; Chromosome 12.
DR Bgee; ENSDARG00000088878; -.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; SSF49842; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 2: Evidence at transcript level;
KW Collagen {ECO:0000256|SAAS:SAAS00562261};
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Secreted {ECO:0000256|SAAS:SAAS00588327};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1 17 {ECO:0000256|SAM:SignalP}.
FT CHAIN 18 267 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5010139455.
FT DOMAIN 127 267 C1q. {ECO:0000259|PROSITE:PS50871}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 126 264 ismart:C1Q [T]
FT MYHIT 127 267 iprf:C1Q [T]
FT MYHIT 85 125 ipfam:Collagen [T]
FT MYHIT 133 261 ipfam:C1q [T]
SQ SEQUENCE 267 AA; 30379 MW; 84C4CDAD66C0C9FC CRC64;
MLMPNLVLLV LVFAKWAEPY ITQNRDGEQD PYEPKDNRRS TEYYRDGSGT ECRRCCDPAE
DPPQFASPHA QYQIVPQINI TILKGEKGDT GERGLHGKSG TSGKNGPRGP HGVKGTKGSV
GAPGESCKSY YAAFSVGRKK ALHSNDYYQT MIFDTEFVNL YGHFNMFTGK FFCYIPGIYF
FSLNAHSWNQ KETYLHLMKN EQEMAILYAQ PSDRSIMQSQ SLMLELERDD QVWVRLFKGE
RENAVFSDDF DTYITFSGYL VKAKSEG
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