Entry euk:Q498W8_DANRE

ID   Q498W8_DANRE            Unreviewed;       167 AA.
AC   Q498W8;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   10-MAY-2017, entry version 68.
DE   SubName: Full=Biogenesis of lysosomal organelles complex-1, subunit 2 {ECO:0000313|Ensembl:ENSDARP00000067750};
DE   SubName: Full=Zgc:111974 {ECO:0000313|EMBL:AAI00046.1};
GN   Name=bloc1s2 {ECO:0000313|Ensembl:ENSDARP00000067750,
GN   ECO:0000313|ZFIN:ZDB-GENE-050809-129};
GN   ORFNames=zgc:111974 {ECO:0000313|EMBL:AAI00046.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI00046.1};
RN   [1] {ECO:0000313|EMBL:AAI00046.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain {ECO:0000313|EMBL:AAI00046.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000067750}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000067750};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000067750, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000067750,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; BX897740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC100045; AAI00046.1; -; mRNA.
DR   UniGene; Dr.48553; -.
DR   STRING; 7955.ENSDARP00000110597; -.
DR   Ensembl; ENSDART00000067751; ENSDARP00000067750; ENSDARG00000046081.
DR   ZFIN; ZDB-GENE-050809-129; bloc1s2.
DR   eggNOG; KOG4559; Eukaryota.
DR   eggNOG; ENOG4111XFP; LUCA.
DR   GeneTree; ENSGT00390000005889; -.
DR   HOGENOM; HOG000111279; -.
DR   HOVERGEN; HBG079627; -.
DR   Proteomes; UP000000437; Chromosome 20.
DR   Bgee; ENSDARG00000046081; -.
DR   GO; GO:1905457; P:negative regulation of lymphoid progenitor cell differentiation; IMP:ZFIN.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:ZFIN.
DR   GO; GO:1902038; P:positive regulation of hematopoietic stem cell differentiation; IMP:ZFIN.
DR   GO; GO:1905455; P:positive regulation of myeloid progenitor cell differentiation; IMP:ZFIN.
DR   InterPro; IPR019269; BLOC1_su2.
DR   Pfam; PF10046; BLOC1_2; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        68    162       ipfam:BLOC1_2 [T]
SQ   SEQUENCE   167 AA;  19003 MW;  B8EE83B3A10D70DD CRC64;
     MDSISKAPAP PTELNLTAEP ENSREATTSD TTENQKPKRP SNNNDGGVET AEEATEPAEP
     DINELCRDMF DKMSVFLQGE LTATCEDYKL LENMNKLTSL KYMEMKDISI NISRNLQDLN
     QKYASLQPYL DQINQIEEQV TALEQAAYKL DTYSKKLEAK FKKLEKR
//