Entry euk:Q32PN8_DANRE

ID   Q32PN8_DANRE            Unreviewed;       126 AA.
AC   Q32PN8;
DT   06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT   06-DEC-2005, sequence version 1.
DT   10-MAY-2017, entry version 91.
DE   SubName: Full=Inhibitor of DNA-binding 4 {ECO:0000313|Ensembl:ENSDARP00000066371};
DE   SubName: Full=Zgc:123214 {ECO:0000313|EMBL:AAI08046.1};
GN   Name=id4 {ECO:0000313|Ensembl:ENSDARP00000066371,
GN   ECO:0000313|ZFIN:ZDB-GENE-051113-208};
GN   Synonyms=zgc:123214 {ECO:0000313|EMBL:AAI08046.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI08046.1};
RN   [1] {ECO:0000313|EMBL:AAI08046.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium {ECO:0000313|EMBL:AAI08046.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000066371}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000066371};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000066371, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000066371,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CR388383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC108045; AAI08046.1; -; mRNA.
DR   RefSeq; NP_001035079.1; NM_001039990.1.
DR   UniGene; Dr.77286; -.
DR   STRING; 7955.ENSDARP00000066371; -.
DR   Ensembl; ENSDART00000066372; ENSDARP00000066371; ENSDARG00000045131.
DR   GeneID; 664761; -.
DR   KEGG; dre:664761; -.
DR   CTD; 3400; -.
DR   ZFIN; ZDB-GENE-051113-208; id4.
DR   eggNOG; ENOG410IVMK; Eukaryota.
DR   eggNOG; ENOG4111QS6; LUCA.
DR   GeneTree; ENSGT00390000000908; -.
DR   HOGENOM; HOG000234788; -.
DR   HOVERGEN; HBG009009; -.
DR   KO; K17695; -.
DR   OMA; HHQRTSI; -.
DR   OrthoDB; EOG091G0VHR; -.
DR   TreeFam; TF326217; -.
DR   Proteomes; UP000000437; Chromosome 16.
DR   Bgee; ENSDARG00000045131; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0036302; P:atrioventricular canal development; IMP:ZFIN.
DR   GO; GO:0003171; P:atrioventricular valve development; IMP:ZFIN.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0003307; P:regulation of Wnt signaling pathway involved in heart development; IMP:ZFIN.
DR   CDD; cd00083; HLH; 1.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR026052; DNA-bd_prot-inh.
DR   PANTHER; PTHR11723; PTHR11723; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN       28     80       BHLH (basic helix-loop-helix).
FT                                {ECO:0000259|PROSITE:PS50888}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        43     81       ipfam:HLH [T]
FT   MYHIT        32     86       ismart:HLH [T]
FT   MYHIT        28     80       iprf:BHLH [T]
SQ   SEQUENCE   126 AA;  14435 MW;  C90555F0C627CBF7 CRC64;
     MKASVPVRPH KLPSSCSQLS LRYLSESSRC KMEDEDLFCL QYDMNDCYSR LKRLVPTIPQ
     DKKVSKVEIL QHVIDYILDL QLALETHPAL LKQTSPPAST RTPLTQINTE QRTTGVNKED
     SLFLCR
//