Entry euk:Q28GD2_XENTR

ID   Q28GD2_XENTR            Unreviewed;       142 AA.
AC   Q28GD2;
DT   04-APR-2006, integrated into UniProtKB/TrEMBL.
DT   04-APR-2006, sequence version 1.
DT   10-MAY-2017, entry version 79.
DE   SubName: Full=Adaptor-related protein complex 2 sigma 1 subunit {ECO:0000313|Ensembl:ENSXETP00000039622};
DE   SubName: Full=Adaptor-related protein complex 2, sigma 1 subunit {ECO:0000313|EMBL:CAJ83655.1};
GN   Name=ap2s1 {ECO:0000313|EMBL:CAJ83655.1,
GN   ECO:0000313|Ensembl:ENSXETP00000039622,
GN   ECO:0000313|Xenbase:XB-GENE-999486};
GN   ORFNames=TEgg070i14.1-001 {ECO:0000313|EMBL:CAJ83655.1};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Silurana.
OX   NCBI_TaxID=8364;
RN   [1] {ECO:0000313|EMBL:CAJ83655.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA   Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA   McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G.,
RA   Voigt J., Zorn A.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAI70868.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula {ECO:0000313|EMBL:AAI70868.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSXETP00000039622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000039622};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
RA   Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
RA   Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
RA   Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
RA   Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
RA   Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
RA   Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
RA   Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
RA   Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [4] {ECO:0000313|Ensembl:ENSXETP00000039622}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
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DR   EMBL; AAMC01014516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAMC01014517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC170868; AAI70868.1; -; mRNA.
DR   EMBL; BC171019; AAI71019.1; -; mRNA.
DR   EMBL; CR761434; CAJ83655.1; -; mRNA.
DR   RefSeq; NP_001016325.1; NM_001016325.2.
DR   UniGene; Str.5120; -.
DR   STRING; 8364.ENSXETP00000039622; -.
DR   Ensembl; ENSXETT00000039622; ENSXETP00000039622; ENSXETG00000018283.
DR   GeneID; 549079; -.
DR   KEGG; xtr:549079; -.
DR   CTD; 1175; -.
DR   Xenbase; XB-GENE-999486; ap2s1.
DR   eggNOG; KOG0935; Eukaryota.
DR   eggNOG; COG5030; LUCA.
DR   GeneTree; ENSGT00530000062839; -.
DR   HOGENOM; HOG000185227; -.
DR   HOVERGEN; HBG050517; -.
DR   KO; K11827; -.
DR   OMA; SFFDNVC; -.
DR   OrthoDB; EOG091G0QZV; -.
DR   TreeFam; TF300139; -.
DR   Reactome; R-XTR-171052; LDL-mediated lipid transport.
DR   Reactome; R-XTR-177504; Retrograde neurotrophin signalling.
DR   Reactome; R-XTR-2132295; MHC class II antigen presentation.
DR   Reactome; R-XTR-3928665; EPH-ephrin mediated repulsion of cells.
DR   Reactome; R-XTR-416993; Trafficking of GluR2-containing AMPA receptors.
DR   Reactome; R-XTR-437239; Recycling pathway of L1.
DR   Reactome; R-XTR-5099900; WNT5A-dependent internalization of FZD4.
DR   Reactome; R-XTR-8856825; Cargo recognition for clathrin-mediated endocytosis.
DR   Reactome; R-XTR-8856828; Clathrin-mediated endocytosis.
DR   Reactome; R-XTR-8866427; VLDLR internalisation and degradation.
DR   Proteomes; UP000008143; Unassembled WGS sequence.
DR   Bgee; ENSXETG00000018283; -.
DR   GO; GO:0030122; C:AP-2 adaptor complex; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR016635; AP_complex_ssu.
DR   InterPro; IPR022775; AP_mu_sigma_su.
DR   InterPro; IPR027156; APS2.
DR   InterPro; IPR000804; Clathrin_sm-chain_CS.
DR   InterPro; IPR011012; Longin-like_dom.
DR   PANTHER; PTHR11753; PTHR11753; 1.
DR   PANTHER; PTHR11753:SF21; PTHR11753:SF21; 1.
DR   Pfam; PF01217; Clat_adaptor_s; 1.
DR   PIRSF; PIRSF015588; AP_complex_sigma; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
DR   PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008143};
KW   Protein transport {ECO:0000256|SAAS:SAAS00017283};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   Transport {ECO:0000256|SAAS:SAAS00017283}.
FT   DOMAIN        1    141       Clat_adaptor_s.
FT                                {ECO:0000259|Pfam:PF01217}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        57     67       ipat:CLAT_ADAPTOR_S [T]
FT   MYHIT         1    141       ipfam:Clat_adaptor_s [T]
SQ   SEQUENCE   142 AA;  17005 MW;  54CDD868D3AF0DE3 CRC64;
     MIRFILIQNR AGKTRLAKWY MQFDDDEKQK LIEEVHAVVT VRDAKHTNFV EFRNFKIIYR
     RYAGLYFCIC VDVTDNNLAY LEAIHNFVEV LNEYFHNVCE LDLVFNFYKV YTVVDEMFLA
     GEIRETSQTK VLKQLLMLQS LE
//