Entry euk:Q05AJ1_DANRE

ID   Q05AJ1_DANRE            Unreviewed;       723 AA.
AC   Q05AJ1;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   10-MAY-2017, entry version 82.
DE   SubName: Full=La ribonucleoprotein domain family, member 4B {ECO:0000313|Ensembl:ENSDARP00000083939};
DE   SubName: Full=Zgc:153918 {ECO:0000313|EMBL:AAI24490.1};
GN   Name=larp4b {ECO:0000313|Ensembl:ENSDARP00000083939,
GN   ECO:0000313|ZFIN:ZDB-GENE-061027-39};
GN   Synonyms=zgc:153918 {ECO:0000313|EMBL:AAI24490.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI24490.1};
RN   [1] {ECO:0000313|EMBL:AAI24490.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Whole {ECO:0000313|EMBL:AAI24490.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAI34835.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testes {ECO:0000313|EMBL:AAI34835.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000083939}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083939};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSDARP00000083939, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083939,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CR376848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC124489; AAI24490.1; -; mRNA.
DR   EMBL; BC134834; AAI34835.1; -; mRNA.
DR   RefSeq; NP_001071030.1; NM_001077562.1.
DR   UniGene; Dr.83457; -.
DR   STRING; 7955.ENSDARP00000083939; -.
DR   Ensembl; ENSDART00000089506; ENSDARP00000083939; ENSDARG00000062146.
DR   GeneID; 563742; -.
DR   KEGG; dre:563742; -.
DR   CTD; 23185; -.
DR   ZFIN; ZDB-GENE-061027-39; larp4b.
DR   eggNOG; KOG2591; Eukaryota.
DR   eggNOG; ENOG410XTHK; LUCA.
DR   GeneTree; ENSGT00530000063417; -.
DR   HOGENOM; HOG000004803; -.
DR   HOVERGEN; HBG055137; -.
DR   KO; K18763; -.
DR   TreeFam; TF321960; -.
DR   Proteomes; UP000000437; Chromosome 24.
DR   Bgee; ENSDARG00000062146; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR006630; La_HTH.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF05383; La; 1.
DR   SMART; SM00715; LA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50961; HTH_LA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q05AJ1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN      138    227       HTH La-type RNA-binding.
FT                                {ECO:0000259|PROSITE:PS50961}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT       150    203       ipfam:La [T]
FT   MYHIT       142    220       ismart:LA [T]
FT   MYHIT       138    227       iprf:HTH_LA [T]
SQ   SEQUENCE   723 AA;  79425 MW;  4CFFA026662CCAA2 CRC64;
     MTSDQEGKTI VEPQVQQSQE AKEKEIPLLE SSKISDLNPN AKAWANYMPK PEASAPTCPD
     SQQSWVEAAD DPSNCISDGY NNSEDKGNWN EEQQVSTSVE LPFAAQPESV YLGSSVIEKG
     IVSNQNTSMK GVDDSDSSRQ LEDLREQLKA TLEFCLSREN LANDMYLISQ MDSDQYVPIV
     TLANLDQIKK LTTDVDLISD ILKTLPLVQV DKCGEKVRPN QNRCIVILRE IPEATPLEEV
     EALFKSDNLP KFINCEFAYN DNWFITFESE ADAQLAYQYL REEVKTFQGK PIKARIKAKA
     IAVNTFVPKN GYRPVDVSSN VQQRYTPYYI PPVYGAQQQF PLYRLVTPQG WSATQSYLDP
     TLVSPFPSPA FINGFAGSPT FKSATSPLTV RHYTHAPRNR NHNKTHIRLP TDRGTTLLEN
     PAAFSTFPTE RIPNGTRPPQ THHLGSRPRL PTGLAYPRRD QVGSGRMEVN GADYSLNAGR
     GRGGFGYRKR RDDNKFPRSG TQSPPPVQER TPSPSFELGL SSFPPLPGAA GNLKPEVKPE
     NSLDNRLSDV VIGAVKDKPL NKDVVTSRVI SGTPKESVQA APAPAAQTPV DHQHSPSPAQ
     TSPTAVEKPK ETQTPAEKCS DTHAAKTTPL SNPVTQEPRK PSYAEICQRI REAPTQQPSA
     DPRAPSSTAE DVKTPDSAER RCKESASAPA KSTATACPRE TVKSQQSPGD RATAGTTASF
     HQS
//